TAC3 and PRB1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TAC3	PRB1
Description		tachykinin precursor 3	proline rich protein BstNI subfamily 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region
	Molecular Function	Signaling Receptor Binding Protein Binding Neuromedin K Receptor Binding Substance K Receptor Binding	Molecular_function
	Biological Process	Tachykinin Receptor Signaling Pathway Neuropeptide Signaling Pathway Female Pregnancy Positive Regulation Of Blood Pressure Positive Regulation Of Flagellated Sperm Motility	Biological_process
Pathways		Tachykinin receptors bind tachykinins G alpha (q) signalling events
Drugs		Copper
Diseases		Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474 31959851) Asthma or allergic disease (pleiotropy) ( 29785011) Menopause (age at onset) ( 26414677) Red cell distribution width ( 28957414) Schizophrenia ( 25056061)
Interacting Genes		12 interacting genes: CCDC90B ELP1 FEZ1 GPRASP1 PRB1 PRH1 PTN TACR1 TACR2 TACR3 UBC UBR1	17 interacting genes: AQP6 ARL13B ASPH FAM209A GPX8 LEUTX RHOU RIC3 SGTB SLC35H1 SLC7A14 TAC3 TMEM237 TMEM80 TMX2 TOP1 UBQLN1
Entrez ID		6866	5542
HPRD ID		08877	01623
Ensembl ID		ENSG00000166863	ENSG00000251655
Uniprot IDs		Q9UHF0	P04280
PDB IDs		1P9F 8JBG
Enriched GO Terms of Interacting Partners?		Tachykinin Receptor Activity Positive Regulation Of Uterine Smooth Muscle Contraction Tachykinin Receptor Signaling Pathway Regulation Of Uterine Smooth Muscle Contraction Regulation Of Microtubule-based Movement Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Cilium Movement Regulation Of Flagellated Sperm Motility Positive Regulation Of Smooth Muscle Contraction Regulation Of Cilium Movement Operant Conditioning Positive Regulation Of Muscle Contraction Sperm Midpiece Positive Regulation Of Synaptic Transmission, Cholinergic Regulation Of Smooth Muscle Contraction Positive Regulation Of Reproductive Process Regulation Of Microtubule-based Process Sperm Head Positive Regulation Of Vascular Permeability Response To Auditory Stimulus Learning Regulation Of Muscle Contraction Positive Regulation Of Blood Pressure Regulation Of Reproductive Process Response To Electrical Stimulus Regulation Of Vascular Permeability Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Positive Regulation Of Ossification Smooth Muscle Contraction Substance K Receptor Activity Regulation Of Muscle System Process Substance P Receptor Activity Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Learning Or Memory Cognition Dendrite Regeneration Angiotensin-mediated Drinking Behavior G Protein-coupled Receptor Catabolic Process Ossification Involved In Bone Remodeling G Protein-coupled Receptor Activity Prolactin Secretion Negative Regulation Of Luteinizing Hormone Secretion Positive Regulation Of Acetylcholine Secretion, Neurotransmission Smooth Muscle Contraction Involved In Micturition TRNA Wobble Base 5-methoxycarbonylmethyl-2-thiouridinylation Regulation Of Acetylcholine Secretion, Neurotransmission Intestine Smooth Muscle Contraction Response To Ozone Response To Estradiol
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