VAMP7 and AP3D1

Number of citations of the paper that reports this interaction (PMID 12853575)
46

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		VAMP7	AP3D1
Gene Name		vesicle-associated membrane protein 7	adaptor-related protein complex 3, delta 1 subunit
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Lamellipodium Cell Junction Secretory Granule Transport Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Platelet Alpha Granule Pseudopodium SNARE Complex Late Endosome Membrane Azurophil Granule Membrane Neuron Projection Intracellular Membrane-bounded Organelle Apical Part Of Cell Synapse Phagocytic Vesicle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Golgi Membrane Nucleoplasm Lysosomal Membrane Golgi Apparatus Endosome Membrane Membrane Membrane Coat Terminal Bouton
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding	Transporter Activity
	Biological Process	Autophagic Vacuole Fusion Exocytosis ER To Golgi Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Endocytosis Vesicle Fusion Phagocytosis, Engulfment Endosome To Lysosome Transport Vesicle-mediated Transport Calcium Ion-dependent Exocytosis Triglyceride Transport SNARE Complex Assembly Golgi To Plasma Membrane Protein Transport Eosinophil Degranulation Neutrophil Degranulation Natural Killer Cell Degranulation Vesicle Fusion With Golgi Apparatus Membrane Organization Regulation Of Protein Targeting To Vacuolar Membrane Positive Regulation Of Histamine Secretion By Mast Cell	Eye Pigment Biosynthetic Process Intracellular Protein Transport Anterograde Axon Cargo Transport Melanosome Organization Protein Localization To Organelle Endosome To Melanosome Transport Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Synaptic Vesicle Membrane Organization Positive Regulation Of NK T Cell Differentiation Regulation Of Sequestering Of Zinc Ion Protein Localization To Membrane
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: AGFG1 ANKRD27 AP3D1 DNAJC5 SNAP23 SNAP25 SNAP29 STX1A STX3 STX4 STX7	9 interactors: AP3S1 AP3S2 ARF1 ARF6 CTGF RUFY1 SLC30A3 VAMP7 VPS41
Entrez ID		6845	8943
HPRD ID		02084	06260
Ensembl ID		ENSG00000124333	ENSG00000065000
Uniprot IDs		P51809	O14617
PDB IDs		2DMW	4AFI
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Organization Synaptic Vesicle Transport Vesicle Fusion Synaptic Vesicle Exocytosis Organelle Fusion Establishment Of Vesicle Localization Vesicle Localization Organelle Localization Neurotransmitter Secretion Membrane Fusion Regulation Of Neurotransmitter Levels Establishment Of Organelle Localization Neurotransmitter Transport Establishment Of Localization In Cell Vesicle-mediated Transport Cellular Localization Synaptic Transmission Exocytosis Vesicle Docking Membrane Docking Membrane Organization Secretion By Cell Cell-cell Signaling Secretion Synaptic Vesicle Priming Transport Intracellular Transport Positive Regulation Of Synaptic Transmission Organelle Organization Protein Transport Establishment Of Protein Localization Long-term Synaptic Potentiation Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface Protein Localization Synaptic Vesicle Docking Regulation Of Synaptic Transmission Cellular Protein Complex Assembly Regulation Of Protein Localization Intracellular Protein Transport Regulation Of Protein Localization To Cell Surface Regulation Of Synaptic Plasticity Glutamate Secretion Regulation Of Cellular Localization Positive Regulation Of Protein Localization To Plasma Membrane Cellular Component Assembly Regulation Of Cellular Component Organization Regulation Of Insulin Secretion Regulation Of Peptide Hormone Secretion	Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Regulation Of Vesicle-mediated Transport Protein Localization Transport Cellular Localization Regulation Of Cellular Component Organization Establishment Of Localization In Cell Anterograde Synaptic Vesicle Transport Regulation Of Endocytosis Anterograde Axon Cargo Transport Establishment Of Vesicle Localization Vesicle Localization Cellular Protein Localization Intracellular Transport Golgi Vesicle Transport Axon Cargo Transport Establishment Of Organelle Localization Intracellular Protein Transport Regulation Of Organelle Organization Regulation Of Actin Cytoskeleton Organization Organelle Fusion Regulation Of Actin Filament-based Process Regulation Of Protein Targeting To Vacuolar Membrane Vacuole Fusion, Non-autophagic Vacuolar Transport Organelle Localization Post-Golgi Vesicle-mediated Transport Regulation Of Cytoskeleton Organization Synaptic Vesicle Transport Organ Senescence Membrane Fusion Microtubule-based Transport Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Triglyceride Transport Extracellular Matrix Constituent Secretion Eosinophil Degranulation Cytoskeleton-dependent Intracellular Transport Response To Anoxia Positive Regulation Of G0 To G1 Transition Movement Of Cell Or Subcellular Component Regulation Of Sequestering Of Zinc Ion Neutrophil Degranulation Positive Regulation Of Cardiac Muscle Contraction Positive Regulation Of Cytoskeleton Organization Vesicle Organization Myeloid Cell Apoptotic Process Regulation Of SNARE Complex Assembly
Tagcloud ?		acidification alters autophagosome compartments correlative docking fourth hallmark hijacking inside intravesicular lc3 localizes multimembrane nonacidic pave pseudotuberculosis replicate replicates traffic ultrastructurally unexpectedly uninfected vacuoles vamp3 vamps vesicle ycvs yersinia	18s actb bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxo38 fbxw2 gapdh genorm h2k2b4 h2ksf1 htatsf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91
Tagcloud (Difference) ?		acidification alters autophagosome compartments correlative docking fourth hallmark hijacking inside intravesicular lc3 localizes multimembrane nonacidic pave pseudotuberculosis replicate replicates traffic ultrastructurally unexpectedly uninfected vacuoles vamp3 vamps vesicle ycvs yersinia	18s actb bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxo38 fbxw2 gapdh genorm h2k2b4 h2ksf1 htatsf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91
Tagcloud (Intersection) ?