VAMP7 and SNAP23

Number of citations of the paper that reports this interaction (PMID 9614185)
58

Data Source:
HPRD (in vitro)

		VAMP7	SNAP23
Gene Name		vesicle-associated membrane protein 7	synaptosomal-associated protein, 23kDa
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Lamellipodium Cell Junction Secretory Granule Transport Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Platelet Alpha Granule Pseudopodium SNARE Complex Late Endosome Membrane Azurophil Granule Membrane Neuron Projection Intracellular Membrane-bounded Organelle Apical Part Of Cell Synapse Phagocytic Vesicle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Plasma Membrane Focal Adhesion SNARE Complex Specific Granule Azurophil Granule Mast Cell Granule Neuron Projection Synapse Extracellular Vesicular Exosome
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Autophagic Vacuole Fusion Exocytosis ER To Golgi Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Endocytosis Vesicle Fusion Phagocytosis, Engulfment Endosome To Lysosome Transport Vesicle-mediated Transport Calcium Ion-dependent Exocytosis Triglyceride Transport SNARE Complex Assembly Golgi To Plasma Membrane Protein Transport Eosinophil Degranulation Neutrophil Degranulation Natural Killer Cell Degranulation Vesicle Fusion With Golgi Apparatus Membrane Organization Regulation Of Protein Targeting To Vacuolar Membrane Positive Regulation Of Histamine Secretion By Mast Cell	Histamine Secretion By Mast Cell Post-Golgi Vesicle-mediated Transport Vesicle Targeting Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Membrane Membrane Organization Membrane Fusion
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Lysosome Vesicle Biogenesis	Translocation of GLUT4 to the plasma membrane trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: AGFG1 ANKRD27 AP3D1 DNAJC5 SNAP23 SNAP25 SNAP29 STX1A STX3 STX4 STX7	34 interactors: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX2 STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP5 VAMP7 VAMP8 WASH2P
Entrez ID		6845	8773
HPRD ID		02084	03962
Ensembl ID		ENSG00000124333	ENSG00000092531
Uniprot IDs		P51809	A8K287 O00161
PDB IDs		2DMW	1NHL 3ZUS
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Organization Synaptic Vesicle Transport Vesicle Fusion Synaptic Vesicle Exocytosis Organelle Fusion Establishment Of Vesicle Localization Vesicle Localization Organelle Localization Neurotransmitter Secretion Membrane Fusion Regulation Of Neurotransmitter Levels Establishment Of Organelle Localization Neurotransmitter Transport Establishment Of Localization In Cell Vesicle-mediated Transport Cellular Localization Synaptic Transmission Exocytosis Vesicle Docking Membrane Docking Membrane Organization Secretion By Cell Cell-cell Signaling Secretion Synaptic Vesicle Priming Transport Intracellular Transport Positive Regulation Of Synaptic Transmission Organelle Organization Protein Transport Establishment Of Protein Localization Long-term Synaptic Potentiation Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface Protein Localization Synaptic Vesicle Docking Regulation Of Synaptic Transmission Cellular Protein Complex Assembly Regulation Of Protein Localization Intracellular Protein Transport Regulation Of Protein Localization To Cell Surface Regulation Of Synaptic Plasticity Glutamate Secretion Regulation Of Cellular Localization Positive Regulation Of Protein Localization To Plasma Membrane Cellular Component Assembly Regulation Of Cellular Component Organization Regulation Of Insulin Secretion Regulation Of Peptide Hormone Secretion	Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle Organization Vesicle-mediated Transport Establishment Of Localization In Cell Exocytosis Cellular Localization Protein Transport Membrane Organization Establishment Of Protein Localization Intracellular Transport Secretion By Cell Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Docking Membrane Docking Secretion Protein Localization Neurotransmitter Secretion Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Synaptic Vesicle Exocytosis Neurotransmitter Transport Synaptic Vesicle Transport Golgi Vesicle Transport Transport Establishment Of Vesicle Localization Vesicle Localization Cellular Protein Localization SNARE Complex Assembly Regulation Of Exocytosis Establishment Of Organelle Localization Organelle Organization Regulation Of Cellular Localization Cell-cell Signaling Organelle Localization Synaptic Transmission Regulation Of Secretion Regulation Of Vesicle-mediated Transport Calcium Ion-dependent Exocytosis Positive Regulation Of Synaptic Transmission Regulation Of Synaptic Vesicle Priming Positive Regulation Of Exocytosis Golgi To Plasma Membrane Protein Transport Positive Regulation Of Transport Neutrophil Degranulation Regulation Of Cellular Component Organization Golgi To Plasma Membrane Transport Regulation Of Synaptic Transmission
Tagcloud ?		acidification alters autophagosome compartments correlative docking fourth hallmark hijacking inside intravesicular lc3 localizes multimembrane nonacidic pave pseudotuberculosis replicate replicates traffic ultrastructurally unexpectedly uninfected vacuoles vamp3 vamps vesicle ycvs yersinia	apical brevin brevins cellubrevin clostridial codistributed cryosections exocytosis exocytotic immunogold insensitive maleimide nem neurotoxin neurotoxins nsf nts proteolyze snare snares syntaxin tent tetanus ti ultrathin vamp vesicle
Tagcloud (Difference) ?		acidification alters autophagosome compartments correlative docking fourth hallmark hijacking inside intravesicular lc3 localizes multimembrane nonacidic pave pseudotuberculosis replicate replicates traffic ultrastructurally unexpectedly uninfected vacuoles vamp3 vamps ycvs yersinia	apical brevin brevins cellubrevin clostridial codistributed cryosections exocytosis exocytotic immunogold insensitive maleimide nem neurotoxin neurotoxins nsf nts proteolyze snare snares syntaxin tent tetanus ti ultrathin vamp
Tagcloud (Intersection) ?		vesicle