VAMP2 and SNAP29

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		VAMP2	SNAP29
Gene Name		vesicle-associated membrane protein 2 (synaptobrevin 2)	synaptosomal-associated protein, 29kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Trans-Golgi Network Cytosol Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Membrane Cell Junction Clathrin-coated Vesicle Secretory Granule Secretory Granule Membrane Synaptic Vesicle Membrane SNARE Complex Cytoplasmic Vesicle Zymogen Granule Membrane Neuron Projection Intracellular Membrane-bounded Organelle Neuron Projection Terminus Synapse Perinuclear Region Of Cytoplasm Clathrin-sculpted Glutamate Transport Vesicle Membrane Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Extracellular Vesicular Exosome Clathrin-sculpted Monoamine Transport Vesicle Membrane	Cytoplasm Centrosome Plasma Membrane Cell Junction SNARE Complex Neuron Projection Synapse
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Calmodulin Binding Phospholipid Binding Syntaxin-1 Binding Syntaxin Binding Protein Self-association Calcium-dependent Protein Binding	SNAP Receptor Activity Syntaxin Binding
	Biological Process	Energy Reserve Metabolic Process Protein Complex Assembly Exocytosis Post-Golgi Vesicle-mediated Transport Vesicle Fusion Synaptic Transmission Neurotransmitter Secretion Pathogenesis Response To Glucose Glutamate Secretion Protein Transport Synaptic Vesicle Exocytosis Vesicle-mediated Transport Calcium Ion-dependent Exocytosis Regulation Of Exocytosis Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Eosinophil Degranulation Neutrophil Degranulation Natural Killer Cell Degranulation Cellular Protein Metabolic Process Small Molecule Metabolic Process Regulation Of Insulin Secretion Long-term Synaptic Potentiation Regulation Of Vesicle-mediated Transport Membrane Organization Membrane Fusion Mucus Secretion Positive Regulation Of Intracellular Protein Transport Regulation Of Histamine Secretion By Mast Cell	Autophagic Vacuole Fusion Exocytosis Vesicle Targeting Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Membrane Membrane Fusion
Pathways		Dopamine Neurotransmitter Release Cycle Integration of energy metabolism Acetylcholine Neurotransmitter Release Cycle Toxicity of botulinum toxin type D (BoNT/D) Golgi Associated Vesicle Biogenesis Translocation of GLUT4 to the plasma membrane GABA synthesis, release, reuptake and degradation Clathrin derived vesicle budding Lysosome Vesicle Biogenesis Peptide hormone metabolism Uptake and actions of bacterial toxins Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Neurotoxicity of clostridium toxins trans-Golgi Network Vesicle Budding Toxicity of botulinum toxin type G (BoNT/G) Regulation of insulin secretion Norepinephrine Neurotransmitter Release Cycle Toxicity of tetanus toxin (TeNT) Toxicity of botulinum toxin type F (BoNT/F) Glutamate Neurotransmitter Release Cycle Toxicity of botulinum toxin type B (BoNT/B) Insulin processing Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		26 interactors: ASNA1 ATP13A2 BAG6 BCAP31 CPLX1 FKBP2 PRKD3 RABAC1 SNAP23 SNAP25 SNAP29 STX11 STX1A STX1B STX2 STX3 STX4 STXBP2 STXBP3 SYP SYPL1 TRPC3 VAMP3 VAMP8 VAPA VAPB	22 interactors: AP2A1 ATF4 CD7 EHD1 EHD3 FAM9B ITSN2 KIFC3 LURAP1 RASSF7 STX12 STX17 STX1A STX3 STX4 STX6 STX7 VAMP1 VAMP2 VAMP4 VAMP5 VAMP7
Entrez ID		6844	9342
HPRD ID		01717	11968
Ensembl ID		ENSG00000220205	ENSG00000099940
Uniprot IDs		F8WCA0 P63027	O95721
PDB IDs		3FIE 3FII 3RK2 3RK3 3RL0
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Fusion Vesicle Organization Organelle Fusion Membrane Fusion Synaptic Vesicle Exocytosis Exocytosis Neurotransmitter Secretion Synaptic Vesicle Transport Vesicle Docking Membrane Organization Membrane Docking Regulation Of Neurotransmitter Levels Neurotransmitter Transport Secretion By Cell Vesicle-mediated Transport Establishment Of Vesicle Localization Vesicle Localization Secretion Cellular Localization Establishment Of Organelle Localization Establishment Of Localization In Cell Cell-cell Signaling Transport Establishment Of Protein Localization Protein Localization Organelle Localization Synaptic Transmission Protein Transport Vesicle Docking Involved In Exocytosis Regulation Of Exocytosis Cell Communication Regulation Of Cellular Localization Signaling Organelle Organization Golgi Vesicle Transport Regulation Of Secretion Intracellular Transport Neutrophil Degranulation Cellular Protein Localization Synaptic Vesicle Docking SNARE Complex Assembly Regulation Of Vesicle-mediated Transport Neutrophil Activation Involved In Immune Response Synaptic Vesicle Priming Positive Regulation Of Synaptic Transmission Leukocyte Degranulation Regulated Secretory Pathway Regulation Of Synaptic Transmission Negative Regulation By Host Of Viral Genome Replication	Vesicle Fusion Organelle Fusion Membrane Fusion Vesicle Organization Vesicle-mediated Transport Membrane Organization Intracellular Protein Transport Establishment Of Localization In Cell Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Cellular Localization Vesicle Docking SNARE Complex Assembly Membrane Docking Exocytosis Protein Localization Endomembrane System Organization Golgi Vesicle Transport Secretion By Cell Post-Golgi Vesicle-mediated Transport Organelle Organization Neurotransmitter Secretion Secretion Transport Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Neurotransmitter Levels Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Exocytosis Regulation Of Protein Localization Neurotransmitter Transport Golgi Organization Regulation Of Vesicle-mediated Transport Establishment Of Protein Localization To Plasma Membrane Endosomal Transport Golgi To Plasma Membrane Protein Transport Regulation Of Cellular Localization Eosinophil Degranulation Synaptic Vesicle Transport Positive Regulation Of Synaptic Transmission Golgi To Plasma Membrane Transport Calcium Ion-dependent Exocytosis Protein Localization To Plasma Membrane Regulation Of Exocytosis Long-term Synaptic Potentiation Golgi Ribbon Formation Protein Complex Assembly Positive Regulation Of Protein Localization To Cell Surface Positive Regulation Of Exocytosis
Tagcloud ?		adipocytes biol cellubrevin conjugate diaminobenzidine encompassing ethylmaleimide fill glut1 glut4 gould gst guanosine horseradish itinerant james livingstone localizes martin permeabilized postendocytic slot snares streptolysin tails tellam thio triphosphate vamp1	92e accumulates architecture asparagine autophagic autophagosomes cednik dispensable distinctive dysgenesis highlighting hop hopscotch ichthyosis keratoderma localizes neuropathy npf nsf organelles palmoplantar phenylalanine routes snare stat92e synaptosomal trafficking uncharacterized unlikely
Tagcloud (Difference) ?		adipocytes biol cellubrevin conjugate diaminobenzidine encompassing ethylmaleimide fill glut1 glut4 gould gst guanosine horseradish itinerant james livingstone martin permeabilized postendocytic slot snares streptolysin tails tellam thio triphosphate vamp1	92e accumulates architecture asparagine autophagic autophagosomes cednik dispensable distinctive dysgenesis highlighting hop hopscotch ichthyosis keratoderma neuropathy npf nsf organelles palmoplantar phenylalanine routes snare stat92e synaptosomal trafficking uncharacterized unlikely
Tagcloud (Intersection) ?		localizes