AARD and KRT27

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AARD	KRT27
Description		alanine and arginine rich domain containing protein	keratin 27
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Response To Testosterone	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Hair Follicle Morphogenesis Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS			Asthma ( 31959851)
Interacting Genes		15 interacting genes: CENPQ CEP57 GRIPAP1 KIAA0753 KRT24 KRT27 LMO4 MAGEB4 NTAQ1 STX1A STX2 STX5 TFIP11 TSGA10 VPS37C	139 interacting genes: AARD ABI2 AMOT ARFIP1 ARHGEF6 ATP6V1D BCAS2 BEX2 BFSP2 C19orf44 C1orf216 C21orf58 CCBE1 CCDC138 CCDC146 CCDC185 CCDC187 CCDC22 CCDC68 CCHCR1 CCNC CEP95 CFAP58 COX5B DPPA3 DTNB DUSP26 EXOC3L1 EXOSC5 FAM107A FAM110A FMNL2 GADD45GIP1 GFAP GNG13 GOLGA1 GPS2 GSTK1 HAPLN2 HDAC4 HGS HOXB9 HSPBP1 ICA1L IGF1R INSR INSRR JOSD1 KANK2 KIAA1217 KLHL38 KRT1 KRT2 KRT20 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT81 KRT82 KRT83 KRT85 KRT86 LKAAEAR1 LMNTD2 MATR3 MBD3L2 MID2 MORN4 MOS MTMR9 NDC80 NDUFAF3 NTAQ1 NUP54 NUP58 ODAD3 OIP5 PBX3 PCDHB14 PNN POLL PPP1R18 PRPH PSMC5 RASAL3 RBM41 RCOR3 RNF39 RTP5 RUNX1T1 SCNM1 SDHAF1 SEMA4C SLC22A5 SLIRP SMARCC2 SMARCD1 SMARCE1 SSC5D SSX3 SUFU SUOX TBRG4 TEAD4 TEDC2 TEX28 THAP7 TNNT1 TRAF3IP3 TRIML2 TSKS TTC23 TXLNB TXN2 USHBP1 USP2 VPS37C WASHC3 XRCC4 ZC3H14 ZFYVE26 ZNF3 ZNF580 ZNF581 ZNF669 ZNF80
Entrez ID		441376	342574
HPRD ID		18830	17244
Ensembl ID		ENSG00000205002	ENSG00000171446
Uniprot IDs		B2RU19 Q4LEZ3	Q7Z3Y8
PDB IDs
Enriched GO Terms of Interacting Partners?		SNARE Complex SNAP Receptor Activity SNARE Binding Vesicle Docking Calcium-dependent Protein Binding Organelle Localization By Membrane Tethering Membrane Docking Vesicle Fusion Organelle Membrane Fusion Vesicle Organization Organelle Fusion Presynaptic Active Zone Membrane Membrane Fusion Structural Molecule Activity Organelle Organization Organelle Localization Myosin Head/neck Binding Protein-N-terminal Glutamine Amidohydrolase Activity Extrinsic Component Of Postsynaptic Early Endosome Membrane Regulation Of Recycling Endosome Localization Within Postsynapse Intracellular Protein Transport Structural Constituent Of Skin Epidermis Endomembrane System Protein Transport Spliceosomal Complex Disassembly Protein-N-terminal Asparagine Amidohydrolase Activity Positive Regulation Of Protein Localization To Kinetochore Negative Regulation Of Receptor Clustering Regulation Of Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Intermediate Filament Organization Membrane Organization Intracellular Protein Localization Positive Regulation Of Norepinephrine Secretion Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Ventral Spinal Cord Interneuron Differentiation U2-type Post-mRNA Release Spliceosomal Complex Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Establishment Of Protein Localization	Intermediate Filament Organization Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Keratinization Keratin Filament Supramolecular Fiber Organization Cytoskeleton Organization Protein Binding Organelle Organization Insulin Receptor Activity Structural Constituent Of Cytoskeleton Insulin Receptor Complex Intermediate Filament Cytoskeleton Structural Molecule Activity Insulin Receptor Substrate Binding Epidermis Development Brahma Complex NpBAF Complex RSC-type Complex NBAF Complex Phosphatidylinositol 3-kinase Binding Nucleosome Disassembly Insulin Binding
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