AARD and KIAA0753

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AARD	KIAA0753
Description		alanine and arginine rich domain containing protein	KIAA0753
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Endoplasmic Reticulum Centrosome Centriole Microtubule Organizing Center Cytosol Cytoskeleton Cilium Centriolar Satellite Ciliary Basal Body
	Molecular Function	Protein Binding	Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Response To Testosterone	Centriole Replication Cilium Assembly Cytosolic Ciliogenesis Protein Localization To Centrosome
Pathways
Drugs
Diseases
GWAS			Familial lung cancer ( 29924316) LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Pulse pressure ( 27841878 28135244 30578418) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		15 interacting genes: CENPQ CEP57 GRIPAP1 KIAA0753 KRT24 KRT27 LMO4 MAGEB4 NTAQ1 STX1A STX2 STX5 TFIP11 TSGA10 VPS37C	20 interacting genes: AARD AIRIM BHLHA9 BRPF1 CCHCR1 CT55 FAM161A GCC1 HGS KIFC3 MNS1 RNF6 ROPN1 SMARCD1 SUOX TCHP TEAD4 USHBP1 ZNF114 ZNF777
Entrez ID		441376	9851
HPRD ID		18830	11106
Ensembl ID		ENSG00000205002	ENSG00000198920
Uniprot IDs		B2RU19 Q4LEZ3	Q2KHM9
PDB IDs
Enriched GO Terms of Interacting Partners?		SNARE Complex SNAP Receptor Activity SNARE Binding Vesicle Docking Calcium-dependent Protein Binding Organelle Localization By Membrane Tethering Membrane Docking Vesicle Fusion Organelle Membrane Fusion Vesicle Organization Organelle Fusion Presynaptic Active Zone Membrane Membrane Fusion Structural Molecule Activity Organelle Organization Organelle Localization Myosin Head/neck Binding Protein-N-terminal Glutamine Amidohydrolase Activity Extrinsic Component Of Postsynaptic Early Endosome Membrane Regulation Of Recycling Endosome Localization Within Postsynapse Intracellular Protein Transport Structural Constituent Of Skin Epidermis Endomembrane System Protein Transport Spliceosomal Complex Disassembly Protein-N-terminal Asparagine Amidohydrolase Activity Positive Regulation Of Protein Localization To Kinetochore Negative Regulation Of Receptor Clustering Regulation Of Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Intermediate Filament Organization Membrane Organization Intracellular Protein Localization Positive Regulation Of Norepinephrine Secretion Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Ventral Spinal Cord Interneuron Differentiation U2-type Post-mRNA Release Spliceosomal Complex Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Establishment Of Protein Localization	Polymeric Cytoskeletal Fiber
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