CDKL5 and SKIV2L

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CDKL5	SKIV2L
Gene Name		cyclin-dependent kinase-like 5	superkiller viralicidic activity 2-like (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Ruffle Membrane Dendrite Cytoplasm Dendritic Growth Cone	Nucleus Nucleoplasm Ski Complex
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity ATP Binding Kinase Activity Rac GTPase Binding	RNA Binding ATP-dependent RNA Helicase Activity ATP Binding
	Biological Process	Neuron Migration Protein Phosphorylation Positive Regulation Of Rac GTPase Activity Positive Regulation Of Axon Extension Protein Autophosphorylation Regulation Of Dendrite Development Positive Regulation Of Dendrite Morphogenesis Regulation Of Cell Cycle	Metabolic Process
Pathways			Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS			Age-related macular degeneration ( 23577725 20861866) Prostate cancer ( 23535732)
Protein-Protein Interactions		1 interactors: SKIV2L	11 interactors: CDK11A CDKL5 EXOSC10 EXOSC4 GALNT13 PMPCA SNRPB TNRC17 TSSK2 WDR1 XRN1
Entrez ID		6792	6499
HPRD ID		02190	02724
Ensembl ID		ENSG00000008086	ENSG00000204351
Uniprot IDs		O76039	Q15477
PDB IDs		4BGQ
Enriched GO Terms of Interacting Partners?			Histone MRNA Metabolic Process Nuclear MRNA Surveillance RNA Surveillance Histone MRNA Catabolic Process RRNA Catabolic Process RRNA Metabolic Process Maturation Of 5.8S RRNA Nuclear-transcribed MRNA Catabolic Process NcRNA Metabolic Process MRNA Catabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay MRNA Metabolic Process RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nucleic Acid Phosphodiester Bond Hydrolysis Ribonucleoprotein Complex Biogenesis Regulation Of Cell Growth Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Aromatic Compound Catabolic Process RNA Phosphodiester Bond Hydrolysis Positive Regulation Of Cell Growth RRNA Processing Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Regulation Of Growth Ribosome Biogenesis Cellular Metabolic Process Protein Autophosphorylation DNA Deamination Positive Regulation Of Growth Dosage Compensation By Inactivation Of X Chromosome Cellular Macromolecule Catabolic Process Intracellular MRNA Localization Dosage Compensation
Tagcloud ?		antithyroglobulin antithyroid aspect autoantibodies basel belonged caucasian deletions differing ft3 ft4 geographical girls karger limit mecp2 meeting references rett rtt subgroup t4 tga thyroglobulin thyroperoxidase thyroxine tsh unanimous upper
Tagcloud (Difference) ?		antithyroglobulin antithyroid aspect autoantibodies basel belonged caucasian deletions differing ft3 ft4 geographical girls karger limit mecp2 meeting references rett rtt subgroup t4 tga thyroglobulin thyroperoxidase thyroxine tsh unanimous upper
Tagcloud (Intersection) ?