LIPE and KATNA1

Number of citations of the paper that reports this interaction (PMID 10445032)
6

Data Source:
HPRD (in vitro, in vivo)

		LIPE	KATNA1
Gene Name		lipase, hormone-sensitive	katanin p60 (ATPase containing) subunit A 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lipid Particle Cytosol Caveola	Spindle Pole Nucleus Nucleoplasm Cytoplasm Lipid Particle Centrosome Microtubule Organizing Center Spindle Microtubule Plasma Membrane Axon Growth Cone Midbody Neuronal Cell Body
	Molecular Function	Triglyceride Lipase Activity Protein Binding Protein Kinase Binding Hormone-sensitive Lipase Activity	Protein Binding ATP Binding Microtubule Binding Microtubule-severing ATPase Activity Dynein Binding Protein Heterodimerization Activity
	Biological Process	Protein Phosphorylation Cholesterol Metabolic Process Lipid Catabolic Process Triglyceride Catabolic Process Long-chain Fatty Acid Catabolic Process Small Molecule Metabolic Process Diacylglycerol Catabolic Process	Microtubule Bundle Formation Neuron Migration Mitotic Nuclear Division Protein Localization Metabolic Process Negative Regulation Of Neuron Projection Development Cytoplasmic Microtubule Organization Microtubule Severing Cell Division
Pathways		Metabolism of lipids and lipoproteins Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis Lipid digestion, mobilization, and transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: FABP4 KATNA1 MAPK1 MAPK3 NSFL1C PLIN1 PRKACA STAR	7 interactors: CLU DYNC1H1 DYRK2 KATNB1 LIPE PAFAH1B1 VPRBP
Entrez ID		3991	11104
HPRD ID		01062	05986
Ensembl ID		ENSG00000079435	ENSG00000186625
Uniprot IDs		Q05469	A8K7S5 O75449
PDB IDs
Enriched GO Terms of Interacting Partners?		Triglyceride Catabolic Process Cellular Response To Growth Hormone Stimulus Acylglycerol Catabolic Process Response To Growth Hormone Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Golgi Inheritance Caveolin-mediated Endocytosis Cellular Response To Peptide Hormone Stimulus Regulation Of Golgi Organization Cellular Response To Peptide Triglyceride Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Neutral Lipid Metabolic Process Regulation Of Early Endosome To Late Endosome Transport Response To Peptide Hormone Cellular Response To Organonitrogen Compound Response To Peptide Cellular Response To Epinephrine Stimulus Cellular Lipid Catabolic Process Cellular Response To Lipopolysaccharide Response To Epinephrine Cellular Response To Molecule Of Bacterial Origin Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Growth Factor Stimulus Cellular Response To Hormone Stimulus JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Response To Growth Factor Platelet Activation Growth Hormone Receptor Signaling Pathway Cellular Response To Catecholamine Stimulus Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Response To Epidermal Growth Factor Regulation Of Cellular Response To Heat Neurotrophin Signaling Pathway Response To Cytokine Regulation Of Protein Kinase Activity Lipid Catabolic Process Lipopolysaccharide-mediated Signaling Pathway Regulation Of Kinase Activity Activation Of Protein Kinase Activity Innate Immune Response Response To Organonitrogen Compound Response To Insulin Regulation Of MAP Kinase Activity Peptidyl-threonine Phosphorylation Response To Exogenous DsRNA	Microtubule-based Movement Cell Competition In A Multicellular Organism Positive Regulation Of Tau-protein Kinase Activity Microglial Cell Proliferation Histone H2A-T120 Phosphorylation Regulation Of Neuronal Signal Transduction G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Neurofibrillary Tangle Assembly Organelle Organization Mitotic Cell Cycle Process Establishment Of Centrosome Localization Mitotic Chromosome Movement Towards Spindle Pole Diacylglycerol Catabolic Process Mitotic Cell Cycle Microtubule-based Process Central Nervous System Myelin Maintenance Intrinsic Apoptotic Signaling Pathway Regulation Of Tau-protein Kinase Activity Positive Regulation Of Microtubule Depolymerization Platelet Activating Factor Metabolic Process Negative Regulation Of Protein Homooligomerization Positive Regulation Of Neuron Projection Development Immune System Process Long-chain Fatty Acid Catabolic Process Positive Regulation Of Inclusion Body Assembly Regulation Of Beta-amyloid Clearance Gliogenesis Lipid Catabolic Process Corpus Callosum Morphogenesis Mitotic Cell Cycle Phase Transition Osteoclast Development Positive Regulation Of Beta-amyloid Formation Cell Cycle Phase Transition Cell Cycle Process Negative Regulation Of NFAT Protein Import Into Nucleus Negative Regulation Of Protein Oligomerization Positive Regulation Of Cell Projection Organization Negative Regulation Of Beta-amyloid Formation Cytoplasmic MRNA Processing Body Assembly Retrograde Axon Cargo Transport Microtubule Severing Mitotic Nuclear Division Nuclear Migration Establishment Of Organelle Localization Positive Regulation Of Neuron Differentiation Leukocyte Differentiation Positive Regulation Of Glycogen Biosynthetic Process Chaperone-mediated Protein Complex Assembly Microglial Cell Activation Alcohol Metabolic Process
Tagcloud ?		abhd5 agpat2 anomaly atgl cgi ctgm dgat1 diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Difference) ?		abhd5 agpat2 anomaly atgl cgi ctgm dgat1 diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Intersection) ?