SSTR5 and GOPC

Number of citations of the paper that reports this interaction (PMID 16012170)
16

Data Source:
BioGRID (pull down)
HPRD (in vivo, in vitro, two hybrid)

		SSTR5	GOPC
Gene Name		somatostatin receptor 5	golgi-associated PDZ and coiled-coil motif containing
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection	Golgi Membrane Cytoplasm Golgi Apparatus Plasma Membrane Postsynaptic Density Membrane Cell Junction Trans-Golgi Network Transport Vesicle Dendrite Protein Complex Postsynaptic Membrane
	Molecular Function	Somatostatin Receptor Activity Neuropeptide Binding	Small GTPase Regulator Activity Frizzled Binding Protein Binding Protein C-terminus Binding Protein Homodimerization Activity Ion Channel Binding
	Biological Process	G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Synaptic Transmission Negative Regulation Of Cell Proliferation Positive Regulation Of Cytokinesis Somatostatin Signaling Pathway Glucose Homeostasis Regulation Of Insulin Secretion Cellular Response To Glucocorticoid Stimulus Cellular Response To Estradiol Stimulus	ER To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Spermatid Nucleus Differentiation Protein Transport Cytoplasmic Sequestering Of CFTR Protein Apical Protein Localization Regulation Of Catalytic Activity Protein Homooligomerization
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS			Colorectal cancer ( 23266556)
Protein-Protein Interactions		8 interactors: ADCY10 CORT DRD2 GOPC PDZK1 PEX5 SST SSTR1	58 interactors: ABCA1 ADRB1 AKIRIN1 ASIC3 BATF BECN1 C17orf67 CCDC102B CD300C CDC42 CDKN2C CERCAM CFTR CLCN3 CSPG5 DPYD FAM90A1 FAM9B FOSL2 FZD5 FZD8 GOLGA3 GRID1 GRID2 HCK IGHG3 JUN KPNA1 LCLAT1 MORN4 MRPL1 MUM1 MYLK MYOCD NUP62 PARK7 PID1 RELA RHOQ RNF183 RNF220 RPL13AP17 RTKN SEMA4G SLC25A18 SPATA8 SSNA1 SSTR5 STARD3 STX6 TGFBR2 VIM VTN ZBTB49 ZNF564 ZNF581 ZNF587 ZSCAN1
Entrez ID		6755	57120
HPRD ID		01677	06024
Ensembl ID		ENSG00000162009	ENSG00000047932
Uniprot IDs		P35346	Q9HD26
PDB IDs			2DC2 2LOB 4E34 4E35
Enriched GO Terms of Interacting Partners?		G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Synaptic Transmission Cerebral Cortex Neuron Differentiation Positive Regulation Of Multicellular Organism Growth Cell-cell Signaling Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Forebrain Development G-protein Coupled Receptor Signaling Pathway Cytoplasmic Sequestering Of CFTR Protein Regulation Of Multicellular Organism Growth Telencephalon Cell Migration Forebrain Cell Migration Spermatogenesis Male Gamete Generation Response To Drug Positive Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Protein Homotetramerization Digestion Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Neuromuscular Process Monocarboxylic Acid Transport Regulation Of Protein Transport Hormone-mediated Signaling Pathway Regulation Of Anion Transport Regulation Of Locomotion Involved In Locomotory Behavior Protein Import Into Peroxisome Matrix, Translocation Negative Regulation Of Dopamine Receptor Signaling Pathway Gamete Generation Positive Regulation Of Developmental Growth Negative Regulation Of Cell Proliferation Regulation Of Establishment Of Protein Localization Cytoplasmic Transport Negative Regulation Of Dopamine Secretion Protein Import Into Peroxisome Matrix, Docking Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Branching Morphogenesis Of A Nerve Neuron Migration Negative Regulation Of Voltage-gated Calcium Channel Activity Orbitofrontal Cortex Development Somatostatin Signaling Pathway Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of Protein Transport Brain Development Regulation Of Protein Localization Sexual Reproduction Head Development Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Protein Homooligomerization Hormone-mediated Apoptotic Signaling Pathway Regulation Of Dopamine Receptor Signaling Pathway	Cellular Response To Stimulus Cellular Response To Organic Substance Response To External Stimulus Myeloid Leukocyte Differentiation Leukocyte Differentiation Response To Organic Substance Cell Surface Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Regulation Of Protein Phosphorylation Response To Stimulus Cellular Process Cell Communication Positive Regulation Of Cellular Biosynthetic Process Regulation Of Binding Positive Regulation Of Transport Regulation Of Cellular Process Cell Differentiation Regulation Of Membrane Potential Myeloid Dendritic Cell Differentiation Cellular Response To Hormone Stimulus Signal Transduction Blood Vessel Morphogenesis Myeloid Dendritic Cell Activation Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of DNA Binding Response To Extracellular Stimulus Negative Regulation Of Protein Phosphorylation Cell Death Death Positive Regulation Of Gene Expression T-helper 17 Cell Lineage Commitment Response To Lipid Regulation Of Phosphorylation Cellular Localization Membrane Hyperpolarization Negative Regulation Of Cell Proliferation Defense Response Regulation Of Signaling Response To Drug Positive Regulation Of DNA Binding Blood Vessel Development Response To Mechanical Stimulus Response To Stress Signaling Response To Cytokine T-helper 17 Cell Differentiation Dendritic Cell Differentiation Response To Other Organism
Tagcloud ?		camk1 centriole dkk1 enah endosome geo gpsm2 inference kcnq3 kpna2 lcn2 lef1 lysosome map2k6 multivesicular nkx2 nr5a1 nup62 ontology phosphoinositide sfrp4 slc4a3 sort1 stx1a subnetwork tbl3 transport tshb ube2c	admissions attained clinicaltrials clinics dbp empowering empowerment equation estimating estimation generalized gov hba1c hong inpatient kong nct01935349 outpatient pep programme registration sbp september service sopc specialist t2dm utilization visits
Tagcloud (Difference) ?		camk1 centriole dkk1 enah endosome geo gpsm2 inference kcnq3 kpna2 lcn2 lef1 lysosome map2k6 multivesicular nkx2 nr5a1 nup62 ontology phosphoinositide sfrp4 slc4a3 sort1 stx1a subnetwork tbl3 transport tshb ube2c	admissions attained clinicaltrials clinics dbp empowering empowerment equation estimating estimation generalized gov hba1c hong inpatient kong nct01935349 outpatient pep programme registration sbp september service sopc specialist t2dm utilization visits
Tagcloud (Intersection) ?