SSTR5 and ADCY10

Number of citations of the paper that reports this interaction (PMID 9694905)
3

Data Source:
HPRD (in vivo)

		SSTR5	ADCY10
Gene Name		somatostatin receptor 5	adenylate cyclase 10 (soluble)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Axon Dendrite Growth Cone Neuronal Cell Body Apical Part Of Cell Basal Part Of Cell Perinuclear Region Of Cytoplasm
	Molecular Function	Somatostatin Receptor Activity Neuropeptide Binding	Magnesium Ion Binding Adenylate Cyclase Activity ATP Binding Manganese Ion Binding ATPase Binding
	Biological Process	G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Synaptic Transmission Negative Regulation Of Cell Proliferation Positive Regulation Of Cytokinesis Somatostatin Signaling Pathway Glucose Homeostasis Regulation Of Insulin Secretion Cellular Response To Glucocorticoid Stimulus Cellular Response To Estradiol Stimulus	CAMP Biosynthetic Process Spermatogenesis Intracellular Signal Transduction Positive Regulation Of Apoptotic Process
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Hedgehog 'off' state Signaling by Hedgehog
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ADCY10 CORT DRD2 GOPC PDZK1 PEX5 SST SSTR1	2 interactors: PTGIR SSTR5
Entrez ID		6755	55811
HPRD ID		01677	05549
Ensembl ID		ENSG00000162009	ENSG00000143199
Uniprot IDs		P35346	Q96PN6
PDB IDs
Enriched GO Terms of Interacting Partners?		G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Synaptic Transmission Cerebral Cortex Neuron Differentiation Positive Regulation Of Multicellular Organism Growth Cell-cell Signaling Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Forebrain Development G-protein Coupled Receptor Signaling Pathway Cytoplasmic Sequestering Of CFTR Protein Regulation Of Multicellular Organism Growth Telencephalon Cell Migration Forebrain Cell Migration Spermatogenesis Male Gamete Generation Response To Drug Positive Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Protein Homotetramerization Digestion Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Neuromuscular Process Monocarboxylic Acid Transport Regulation Of Protein Transport Hormone-mediated Signaling Pathway Regulation Of Anion Transport Regulation Of Locomotion Involved In Locomotory Behavior Protein Import Into Peroxisome Matrix, Translocation Negative Regulation Of Dopamine Receptor Signaling Pathway Gamete Generation Positive Regulation Of Developmental Growth Negative Regulation Of Cell Proliferation Regulation Of Establishment Of Protein Localization Cytoplasmic Transport Negative Regulation Of Dopamine Secretion Protein Import Into Peroxisome Matrix, Docking Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Branching Morphogenesis Of A Nerve Neuron Migration Negative Regulation Of Voltage-gated Calcium Channel Activity Orbitofrontal Cortex Development Somatostatin Signaling Pathway Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of Protein Transport Brain Development Regulation Of Protein Localization Sexual Reproduction Head Development Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Protein Homooligomerization Hormone-mediated Apoptotic Signaling Pathway Regulation Of Dopamine Receptor Signaling Pathway	G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Somatostatin Signaling Pathway Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of Cell Proliferation Positive Regulation Of CAMP-mediated Signaling Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Response To Lipid Cell-cell Signaling Cellular Response To Estradiol Stimulus Regulation Of CAMP-mediated Signaling Cellular Response To Estrogen Stimulus G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytokinesis Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Cell Proliferation Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Cellular Response To Glucocorticoid Stimulus Cellular Response To Corticosteroid Stimulus Regulation Of Cytokinesis Positive Regulation Of CAMP Biosynthetic Process Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Neuropeptide Signaling Pathway Regulation Of CAMP Metabolic Process Regulation Of Smooth Muscle Cell Proliferation Response To Estradiol Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cell Division Response To Organic Substance Hormone-mediated Signaling Pathway Response To Glucocorticoid Response To Corticosteroid Cellular Response To Steroid Hormone Stimulus Regulation Of Insulin Secretion Regulation Of Signaling Glucose Homeostasis Cell Surface Receptor Signaling Pathway Response To Estrogen Regulation Of Peptide Hormone Secretion Positive Regulation Of Cell Cycle Process Regulation Of Cell Division Regulation Of Hormone Secretion
Tagcloud ?		camk1 centriole dkk1 enah endosome geo gpsm2 inference kcnq3 kpna2 lcn2 lef1 lysosome map2k6 multivesicular nkx2 nr5a1 nup62 ontology phosphoinositide sfrp4 slc4a3 sort1 stx1a subnetwork tbl3 transport tshb ube2c
Tagcloud (Difference) ?		camk1 centriole dkk1 enah endosome geo gpsm2 inference kcnq3 kpna2 lcn2 lef1 lysosome map2k6 multivesicular nkx2 nr5a1 nup62 ontology phosphoinositide sfrp4 slc4a3 sort1 stx1a subnetwork tbl3 transport tshb ube2c
Tagcloud (Intersection) ?