SQLE and CREB3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SQLE	CREB3
Gene Name		squalene epoxidase	cAMP responsive element binding protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Golgi Membrane Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Integral Component Of Membrane Nuclear Body Integral Component Of Endoplasmic Reticulum Membrane Neuronal Cell Body
	Molecular Function	Squalene Monooxygenase Activity Flavin Adenine Dinucleotide Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding CAMP Response Element Binding Protein Binding CCR1 Chemokine Receptor Binding CAMP Response Element Binding Protein Homodimerization Activity Protein Dimerization Activity
	Biological Process	Cholesterol Biosynthetic Process Cellular Aromatic Compound Metabolic Process Response To Organic Substance Sterol Biosynthetic Process Small Molecule Metabolic Process Oxidation-reduction Process	Regulation Of Cell Growth Positive Regulation Of Defense Response To Virus By Host Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Chemotaxis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Viral Process Establishment Of Viral Latency Release From Viral Latency Positive Regulation Of Cell Migration Response To Endoplasmic Reticulum Stress Regulation Of Cell Proliferation Cytoplasmic Sequestering Of Transcription Factor Negative Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Induction Of Positive Chemotaxis Positive Regulation Of Calcium Ion Transport Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Deacetylase Activity Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) Cholesterol biosynthesis Metabolism of lipids and lipoproteins Activation of gene expression by SREBF (SREBP)
Drugs		Naftifine Terbinafine Butenafine Ellagic Acid
Diseases
GWAS
Protein-Protein Interactions		3 interactors: ALDOC CREB3 ZNF641	25 interactors: APPBP2 ATF3 ATF4 BCAT2 BNIP2 CCR1 CEBPG CLP1 CREB3L1 CREB3L3 DDIT3 EMD HCFC1 HDAC3 JUN MALL NFE2L2 NFE2L3 NFIL3 OS9 RABAC1 RRAS2 SQLE STX8 TTLL5
Entrez ID		6713	10488
HPRD ID		11802	07339
Ensembl ID		ENSG00000104549	ENSG00000107175
Uniprot IDs		Q14534 Q5HYI4 Q9UNR6	O43889
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Release From Viral Latency Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of Deacetylase Activity Establishment Of Viral Latency Positive Regulation Of Monocyte Chemotaxis Protein Heterotetramerization Regulation Of Monocyte Chemotaxis Positive Regulation Of Defense Response To Virus By Host Induction Of Positive Chemotaxis Fructose Metabolic Process Cytoplasmic Sequestering Of Transcription Factor Cytoplasmic Sequestering Of Protein Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Defense Response To Virus By Host Positive Regulation Of Positive Chemotaxis Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus	Response To Endoplasmic Reticulum Stress Transcription From RNA Polymerase II Promoter Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Unfolded Protein Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Positive Regulation Of Gene Expression Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Transcription, DNA-templated Regulation Of DNA-templated Transcription In Response To Stress RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Gene Expression Biosynthetic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Cellular Response To Stress Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Cellular Nitrogen Compound Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nuclease Activity Regulation Of Phosphorylation Circadian Rhythm Negative Regulation Of Biosynthetic Process Positive Regulation Of Neuron Apoptotic Process Response To Stress Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Regulation Of Gene Expression Positive Regulation Of Neuron Death Regulation Of Phosphorus Metabolic Process
Tagcloud ?		activin alp c1orf19 cdm chsy cobblestone cryab csrp1 dusp6 epas1 foetal gfpt2 grem1 hmgcs1 immunocytochemistry intermediary morphogenetic mt1x osr2 postn ppl rabgap1 sc4mol sox sox15 srgn stro therein wif1	atf6 beyond bzip elucidate endoplasmic expands inducers intramembrane knockouts l4 mammals members microarray proteolysis proteolytic proteolytically recognition reticulum rnai screens similarity spectrum stimulate subfamily thought tumorigenesis unfolded upr
Tagcloud (Difference) ?		activin alp c1orf19 cdm chsy cobblestone cryab csrp1 dusp6 epas1 foetal gfpt2 grem1 hmgcs1 immunocytochemistry intermediary morphogenetic mt1x osr2 postn ppl rabgap1 sc4mol sox sox15 srgn stro therein wif1	atf6 beyond bzip elucidate endoplasmic expands inducers intramembrane knockouts l4 mammals members microarray proteolysis proteolytic proteolytically recognition reticulum rnai screens similarity spectrum stimulate subfamily thought tumorigenesis unfolded upr
Tagcloud (Intersection) ?