CREB3 and TTLL5

Number of citations of the paper that reports this interaction (PubMedID 20546900)
0

Data Source:
BioGRID (two hybrid)

		CREB3	TTLL5
Description		cAMP responsive element binding protein 3	tubulin tyrosine ligase like 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Chromatin Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Nuclear Body Neuronal Cell Body RNA Polymerase II Transcription Regulator Complex	Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Microtubule Plasma Membrane Cilium Ciliary Basal Body Cell Projection
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coregulator Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding CAMP Response Element Binding Protein Binding CCR1 Chemokine Receptor Binding Identical Protein Binding Protein Homodimerization Activity Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	Nucleotide Binding ATP Binding Tubulin Binding Ligase Activity Metal Ion Binding Tubulin-glutamic Acid Ligase Activity Protein-glutamic Acid Ligase Activity, Initiating Protein-glutamic Acid Ligase Activity, Elongating
	Biological Process	Regulation Of Cell Growth DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Chemotaxis Response To Unfolded Protein Release From Viral Latency Positive Regulation Of Cell Migration Endoplasmic Reticulum Unfolded Protein Response Response To Endoplasmic Reticulum Stress Regulation Of Cell Population Proliferation Regulation Of Apoptotic Process Negative Regulation Of Cell Cycle Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Induction Of Positive Chemotaxis Positive Regulation Of Calcium Ion Transport Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Deacetylase Activity Integrated Stress Response Signaling Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Sperm Axoneme Assembly Retina Development In Camera-type Eye
Pathways		CREB3 factors activate genes CREB3 factors activate genes	Carboxyterminal post-translational modifications of tubulin
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Appendicular lean mass ( 33097823) Height ( 21998595) Large artery stroke ( 24262325) Lead levels ( 26025379)
Interacting Genes		205 interacting genes: ABHD16A ACKR2 ACSF2 ACSL5 ADTRP AGER AGPAT3 ALG3 ALG8 APH1A APOA2 APOD APPBP2 AQP1 AQP2 AQP4 AQP5 ATF3 ATF4 ATP6AP2 ATP6V0C BCAP29 BCAT2 BCL2L1 BIK BNIP2 BNIP3 BTN2A2 C2 C3orf52 CACFD1 CCR1 CD207 CD82 CDS2 CEBPG CELA3A CES1 CFHR5 CGRRF1 CHMP7 CLCN7 CLDN19 CLDND2 CLP1 CMTM5 CNPY3 CREB3L1 CREB3L3 CT45A5 CTSW CYB561 CYB5B CYBC1 CYBRD1 CYP4F2 DDIT3 DNAJC30 DOLK DRAM1 EBP EMC6 EMD ERG28 FA2H FAM3A FAM3C FDFT1 FDPS FIS1 FMO1 FMO3 FXYD3 FXYD6 GJA1 GJB2 GYPA HCFC1 HDAC3 HMOX1 HVCN1 ICAM4 IGFBP5 ITM2B JUN KCNK1 KLHL30-AS1 KRTCAP2 LAT LHFPL5 LILRB5 LMBR1L LMNA LPCAT2 LTA MAL2 MALL MARCHF5 MFSD11 MGST2 MRPL57 MS4A1 MYADM NAA10 NDUFB6 NEU1 NFE2L2 NFE2L3 NFIL3 NKG7 NRG4 ORMDL1 OS9 P4HA2 PLLP PLN PLP1 PLPP1 PLTP PMP22 PNLIPRP1 PSENEN PTCH1 PTDSS1 PTPN9 RAB23 RABAC1 RHEB RIMS3 RPRM RPS3A RRAS2 RUSF1 SACM1L SAR1B SCAMP4 SCAMP5 SCLY SCP2 SEC22B SEC61G SELENOK SERINC1 SFT2D2 SFTPC SFXN3 SHMT2 SLC19A3 SLC29A1 SLC29A2 SLC29A3 SLC2A3 SLC2A4 SLC30A2 SLC35H1 SLC38A1 SLC39A13 SLC41A2 SLC41A3 SLC49A3 SLC50A1 SLC61A1 SLC7A9 SPOCK3 SQLE ST6GAL2 STARD3 STX7 STX8 SYNGR1 SYNPR TAP1 TECR TIMM17B TIMM23B TM4SF4 TMEM100 TMEM115 TMEM140 TMEM14A TMEM14B TMEM14C TMEM19 TMEM203 TMEM222 TMEM230 TMEM234 TMEM243 TMEM51 TMEM54 TRAM1 TRAM1L1 TSPAN2 TSPAN4 TSPAN7 TTLL5 UBE2J1 UNC50 USE1 VKORC1 VTI1B YIPF2 ZDHHC11 ZDHHC21 ZDHHC9	4 interacting genes: CDKN1A CREB3 FXR1 NRIP1
Entrez ID		10488	23093
HPRD ID		07339	08309
Ensembl ID		ENSG00000107175	ENSG00000119685
Uniprot IDs		O43889	Q6EMB2
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Protein Binding Transmembrane Transport Chemical Homeostasis Small Molecule Biosynthetic Process Endomembrane System Lipid Biosynthetic Process Homeostatic Process Uracil Transmembrane Transport Pyrimidine Nucleobase Transmembrane Transport Uracil Transmembrane Transporter Activity Lipid Metabolic Process Golgi Apparatus Golgi Membrane Structural Constituent Of Myelin Sheath Response To Endoplasmic Reticulum Stress Integrated Stress Response Signaling Cytidine Transport Guanine Transport Adenosine Transport Cytidine Transmembrane Transporter Activity Guanine Transmembrane Transporter Activity Inosine Transport Guanine Transmembrane Transport Intracellular Chemical Homeostasis Plasma Membrane Steroid Biosynthetic Process Apical Plasma Membrane Cellular Homeostasis Sterol Biosynthetic Process Lysosomal Membrane Pyrimidine-containing Compound Transmembrane Transport Small Molecule Metabolic Process Pyrimidine Nucleoside Transport Nucleoside Transmembrane Transporter Activity Uridine Transmembrane Transporter Activity Uridine Transmembrane Transport Water Channel Activity Nucleoside Transport Nucleoside Transmembrane Transport Pyrimidine Nucleobase Transport Membrane Organization Regulation Of Lipid Transport Transmembrane Transporter Activity Purine Nucleobase Transmembrane Transport Chloride Channel Inhibitor Activity Protein Palmitoylation Organophosphate Biosynthetic Process	Positive Regulation Of Nucleobase-containing Compound Metabolic Process Ovarian Follicle Rupture Positive Regulation Of Deacetylase Activity Nucleolus PCNA-p21 Complex Negative Regulation Of Cardiac Muscle Tissue Regeneration Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Oncogene-induced Cell Senescence Stress-induced Premature Senescence Cellular Response To Cell-matrix Adhesion RNA Strand Annealing Activity Nuclear Pore Localization Intracellular Membraneless Organelle CCR1 Chemokine Receptor Binding Release From Viral Latency Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Growth Nuclear Body Cellular Response To UV-B Negative Regulation Of Cyclin-dependent Protein Kinase Activity Positive Regulation Of Catalytic Activity Negative Regulation Of Cell Cycle Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Replicative Senescence Costamere Positive Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Long-term Synaptic Potentiation Ribonucleoprotein Granule Nuclear Pore Organization Positive Regulation Of MiRNA-mediated Gene Silencing Nuclear Pore Complex Assembly Ovulation Nuclear Glucocorticoid Receptor Binding Induction Of Positive Chemotaxis CAMP Response Element Binding Protein Binding Mitotic G1 DNA Damage Checkpoint Signaling Nuclear Retinoic Acid Receptor Binding Mitotic G1/S Transition Checkpoint Signaling Nuclear Retinoid X Receptor Binding Translation Regulator Activity Regulation Of Circadian Sleep/wake Cycle, Sleep Positive Regulation Of RNA Metabolic Process Pore Complex Assembly Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Macromolecule Biosynthetic Process Response To UV-B Regulation Of Macromolecule Biosynthetic Process
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