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SQLE and ZNF641
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
SQLE
ZNF641
Gene Name
squalene epoxidase
zinc finger protein 641
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Nucleoplasm
Cytoplasm
Molecular Function
Squalene Monooxygenase Activity
Flavin Adenine Dinucleotide Binding
Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
DNA Binding
Metal Ion Binding
Biological Process
Cholesterol Biosynthetic Process
Cellular Aromatic Compound Metabolic Process
Response To Organic Substance
Sterol Biosynthetic Process
Small Molecule Metabolic Process
Oxidation-reduction Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
Pathways
Regulation of cholesterol biosynthesis by SREBP (SREBF)
Cholesterol biosynthesis
Metabolism of lipids and lipoproteins
Activation of gene expression by SREBF (SREBP)
Generic Transcription Pathway
Drugs
Naftifine
Terbinafine
Butenafine
Ellagic Acid
Diseases
GWAS
Protein-Protein Interactions
3 interactors:
ALDOC
CREB3
ZNF641
2 interactors:
KDM1A
SQLE
Entrez ID
6713
121274
HPRD ID
11802
08711
Ensembl ID
ENSG00000104549
ENSG00000167528
Uniprot IDs
Q14534
Q5HYI4
Q9UNR6
Q96N77
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
Release From Viral Latency
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response
Fructose 1,6-bisphosphate Metabolic Process
Positive Regulation Of Deacetylase Activity
Establishment Of Viral Latency
Positive Regulation Of Monocyte Chemotaxis
Protein Heterotetramerization
Regulation Of Monocyte Chemotaxis
Positive Regulation Of Defense Response To Virus By Host
Induction Of Positive Chemotaxis
Fructose Metabolic Process
Cytoplasmic Sequestering Of Transcription Factor
Cytoplasmic Sequestering Of Protein
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Regulation Of Defense Response To Virus By Host
Positive Regulation Of Positive Chemotaxis
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus
Regulation Of Primitive Erythrocyte Differentiation
Negative Regulation Of Histone H3-K4 Methylation
Histone H3-K9 Demethylation
Histone H3-K4 Demethylation
Positive Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Hormone Biosynthetic Process
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Negative Regulation Of Histone H3-K9 Methylation
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Granulocyte Differentiation
Regulation Of Megakaryocyte Differentiation
Negative Regulation Of Histone Methylation
Positive Regulation Of Erythrocyte Differentiation
Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Regulation Of Histone H3-K4 Methylation
Negative Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Hormone Biosynthetic Process
Regulation Of Hematopoietic Progenitor Cell Differentiation
Cholesterol Biosynthetic Process
Histone Lysine Demethylation
Regulation Of Hormone Metabolic Process
Histone Demethylation
Regulation Of Erythrocyte Differentiation
Protein Demethylation
Sterol Biosynthetic Process
Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of DNA Binding
Oxidation-reduction Process
Regulation Of Histone Methylation
Positive Regulation Of Neural Precursor Cell Proliferation
Pituitary Gland Development
Negative Regulation Of Protein Binding
Demethylation
Positive Regulation Of Stem Cell Proliferation
Positive Regulation Of Myeloid Cell Differentiation
Regulation Of DNA Binding
Negative Regulation Of Chromosome Organization
Diencephalon Development
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Binding
Regulation Of Neural Precursor Cell Proliferation
Cholesterol Metabolic Process
Regulation Of Stem Cell Proliferation
Myeloid Leukocyte Differentiation
Steroid Biosynthetic Process
Regulation Of Embryonic Development
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud
?
activin
alp
c1orf19
cdm
chsy
cobblestone
cryab
csrp1
dusp6
epas1
foetal
gfpt2
grem1
hmgcs1
immunocytochemistry
intermediary
morphogenetic
mt1x
osr2
postn
ppl
rabgap1
sc4mol
sox
sox15
srgn
stro
therein
wif1
Tagcloud (Difference)
?
activin
alp
c1orf19
cdm
chsy
cobblestone
cryab
csrp1
dusp6
epas1
foetal
gfpt2
grem1
hmgcs1
immunocytochemistry
intermediary
morphogenetic
mt1x
osr2
postn
ppl
rabgap1
sc4mol
sox
sox15
srgn
stro
therein
wif1
Tagcloud (Intersection)
?