CREB3 and HCFC1

Number of citations of the paper that reports this interaction (PMID 9389645)
58

Data Source:
HPRD (in vitro, in vivo)

		CREB3	HCFC1
Gene Name		cAMP responsive element binding protein 3	host cell factor C1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Integral Component Of Membrane Nuclear Body Integral Component Of Endoplasmic Reticulum Membrane Neuronal Cell Body	Histone Acetyltransferase Complex Nucleus Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Cytoplasm Mitochondrion Membrane Neuronal Cell Body Set1C/COMPASS Complex SAGA-type Complex MLL5-L Complex MLL1 Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding CAMP Response Element Binding Protein Binding CCR1 Chemokine Receptor Binding CAMP Response Element Binding Protein Homodimerization Activity Protein Dimerization Activity	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Identical Protein Binding Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Histone Acetyltransferase Activity (H4-K16 Specific)
	Biological Process	Regulation Of Cell Growth Positive Regulation Of Defense Response To Virus By Host Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Chemotaxis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Viral Process Establishment Of Viral Latency Release From Viral Latency Positive Regulation Of Cell Migration Response To Endoplasmic Reticulum Stress Regulation Of Cell Proliferation Cytoplasmic Sequestering Of Transcription Factor Negative Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Induction Of Positive Chemotaxis Positive Regulation Of Calcium Ion Transport Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Deacetylase Activity Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Organelle Organization Mitochondrion Organization Cell Cycle Positive Regulation Of Gene Expression Release From Viral Latency Regulation Of Protein Complex Assembly Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Cell Cycle Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Stabilization
Pathways			Chromatin modifying enzymes Organelle biogenesis and maintenance Chromatin organization Transcriptional activation of mitochondrial biogenesis HATs acetylate histones Mitochondrial biogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		25 interactors: APPBP2 ATF3 ATF4 BCAT2 BNIP2 CCR1 CEBPG CLP1 CREB3L1 CREB3L3 DDIT3 EMD HCFC1 HDAC3 JUN MALL NFE2L2 NFE2L3 NFIL3 OS9 RABAC1 RRAS2 SQLE STX8 TTLL5	31 interactors: ASF1B CLP1 CREB3 CREBZF E2F1 E2F3 E2F4 EGR2 GABPA GABPB1 HCFC1R1 HSPA1A JUN KMT2A MED25 NFE2L1 OGT PDCD2 POU2F1 PPARGC1A PPARGC1B PPP1CC PSIP1 SETD7 SIN3A SP1 TAF9 THAP11 THAP7 YY1 ZBTB17
Entrez ID		10488	3054
HPRD ID		07339	02061
Ensembl ID		ENSG00000107175	ENSG00000172534
Uniprot IDs		O43889	P51610
PDB IDs			4GO6
Enriched GO Terms of Interacting Partners?		Response To Endoplasmic Reticulum Stress Transcription From RNA Polymerase II Promoter Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Response To Unfolded Protein Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Positive Regulation Of Gene Expression Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Transcription, DNA-templated Regulation Of DNA-templated Transcription In Response To Stress RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Gene Expression Biosynthetic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Cellular Response To Stress Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Cellular Nitrogen Compound Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nuclease Activity Regulation Of Phosphorylation Circadian Rhythm Negative Regulation Of Biosynthetic Process Positive Regulation Of Neuron Apoptotic Process Response To Stress Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Regulation Of Gene Expression Positive Regulation Of Neuron Death Regulation Of Phosphorus Metabolic Process	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Cellular Metabolic Process Regulation Of Cellular Process Rhythmic Process Negative Regulation Of Cellular Metabolic Process Response To Organic Substance Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Metabolic Process Cellular Response To Stress Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process DNA-templated Transcription, Initiation Response To Oxidative Stress Cellular Response To Organic Substance Circadian Rhythm Regulation Of Myeloid Cell Differentiation Positive Regulation Of Myeloid Cell Differentiation Circadian Regulation Of Gene Expression Cellular Response To Oxidative Stress Regulation Of Cell Proliferation
Tagcloud ?		atf6 beyond bzip elucidate endoplasmic expands inducers intramembrane knockouts l4 mammals members microarray proteolysis proteolytic proteolytically recognition reticulum rnai screens similarity spectrum stimulate subfamily thought tumorigenesis unfolded upr	capd3 capg2 condensin conjunction demethylase demethylases dismissal e2f1 ever expanding h3k27me2 h3k4me2 h3k9me1 h4k20me1 intimate jmjc jumonji ncapd3 ncapg2 phd phf8 prophase recognizing removing seq set1a setd1a smc
Tagcloud (Difference) ?		atf6 beyond bzip elucidate endoplasmic expands inducers intramembrane knockouts l4 mammals members microarray proteolysis proteolytic proteolytically recognition reticulum rnai screens similarity spectrum stimulate subfamily thought tumorigenesis unfolded upr	capd3 capg2 condensin conjunction demethylase demethylases dismissal e2f1 ever expanding h3k27me2 h3k4me2 h3k9me1 h4k20me1 intimate jmjc jumonji ncapd3 ncapg2 phd phf8 prophase recognizing removing seq set1a setd1a smc
Tagcloud (Intersection) ?