SPTBN2 and CELSR3

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		SPTBN2	CELSR3
Gene Name		spectrin, beta, non-erythrocytic 2	cadherin, EGF LAG seven-pass G-type receptor 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Spectrin Apical Plasma Membrane Cell Junction Neuronal Cell Body	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Phospholipid Binding	G-protein Coupled Receptor Activity Calcium Ion Binding Protein Binding
	Biological Process	Axon Guidance Synapse Assembly Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cerebellar Purkinje Cell Layer Morphogenesis Adult Behavior Multicellular Organism Growth Actin Filament Capping	Neuron Migration Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules G-protein Coupled Receptor Signaling Pathway Axonal Fasciculation Regulation Of Protein Localization Cilium Assembly
Pathways		Interaction between L1 and Ankyrins Axon guidance MHC class II antigen presentation L1CAM interactions NCAM signaling for neurite out-growth Adaptive Immune System
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		9 interactors: ACTA1 ACTB ACTR1A APC CELSR3 DCTN1 MINK1 SPTA1 UNC13B	11 interactors: CLUH DST IFT140 SCAPER SGSM2 SPTBN2 SPTBN4 SWAP70 TRIP12 TSPYL4 UACA
Entrez ID		6712	1951
HPRD ID		05404	09179
Ensembl ID		ENSG00000173898	ENSG00000008300
Uniprot IDs		O15020	Q9NYQ7
PDB IDs		1WJM 1WYQ
Enriched GO Terms of Interacting Partners?		Organelle Organization Nervous System Development Movement Of Cell Or Subcellular Component Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis System Development Neuron Development Cell Development Cell Morphogenesis Multicellular Organismal Development Anatomical Structure Development Neuron Differentiation Cell Projection Organization Axon Development Immune System Process Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Morphogenesis Developmental Process Anatomical Structure Morphogenesis Cell Morphogenesis Involved In Differentiation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Generation Of Neurons Neurogenesis Homotypic Cell-cell Adhesion Regulation Of Protein Complex Assembly T Cell Differentiation In Thymus Cellular Component Assembly Positive Regulation Of Synaptic Vesicle Priming Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cell Differentiation Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Cytoskeleton Organization Negative Regulation Of Protein Complex Disassembly Cell Adhesion Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Protein Depolymerization Positive Regulation Of Synaptic Vesicle Exocytosis Skeletal Muscle Fiber Adaptation Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Locomotion Single Organismal Cell-cell Adhesion Axonogenesis G2/M Transition Of Mitotic Cell Cycle Regulation Of Protein Complex Disassembly Actin Cytoskeleton Organization Response To Stimulus Regulation Of Cell Adhesion Vesicle-mediated Transport	Actin Filament Capping Negative Regulation Of Actin Filament Depolymerization Regulation Of Organelle Organization Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Negative Regulation Of Protein Polymerization Negative Regulation Of Protein Complex Disassembly Regulation Of Protein Depolymerization Regulation Of Protein Complex Disassembly Negative Regulation Of Histone H2A K63-linked Ubiquitination Late Endosome To Golgi Transport Negative Regulation Of Protein Complex Assembly Regulation Of Histone Ubiquitination Negative Regulation Of Protein K63-linked Ubiquitination Intracellular Distribution Of Mitochondria Negative Regulation Of Cytoskeleton Organization Adult Behavior Movement Of Cell Or Subcellular Component Regulation Of Protein K63-linked Ubiquitination Regulation Of Actin Filament Polymerization Intraciliary Retrograde Transport Negative Regulation Of Double-strand Break Repair Negative Regulation Of DNA Repair Clustering Of Voltage-gated Sodium Channels Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Negative Regulation Of Heart Rate Cell Projection Morphogenesis Cytoskeletal Anchoring At Plasma Membrane Cell Part Morphogenesis Neuronal Ion Channel Clustering Maintenance Of Cell Polarity Hemidesmosome Assembly Organelle Organization Cellular Component Assembly Protein Localization To Cilium Regulation Of Cellular Component Organization Mitochondrion Distribution
Tagcloud ?			avulsed avulsion biceps bpi brachial brachii c5 c7 corticospinal cst elbow electromyogram emg emx1 flexion fostering hamper innervation mbp motoneuron myelin nerves neuromuscular nmj nmjs plexus remyelination sheaths tore
Tagcloud (Difference) ?			avulsed avulsion biceps bpi brachial brachii c5 c7 corticospinal cst elbow electromyogram emg emx1 flexion fostering hamper innervation mbp motoneuron myelin nerves neuromuscular nmj nmjs plexus remyelination sheaths tore
Tagcloud (Intersection) ?