MSN and NCF1

Number of citations of the paper that reports this interaction (PMID 11716484)
20

Data Source:
BioGRID (affinity chromatography technology, pull down)

		MSN	NCF1
Gene Name		moesin	neutrophil cytosolic factor 1
Image
Gene Ontology Annotations	Cellular Component	Uropod Extracellular Space Cytoplasm Cytoskeleton Plasma Membrane Microvillus Focal Adhesion Basolateral Plasma Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Filopodium Microvillus Membrane Vesicle Apical Part Of Cell Extracellular Vesicular Exosome Cell Periphery Blood Microparticle	Rough Endoplasmic Reticulum Golgi Apparatus Cytosol Extrinsic Component Of Membrane Dendrite Phagolysosome NADPH Oxidase Complex Neuronal Cell Body
	Molecular Function	Double-stranded RNA Binding Actin Binding Receptor Binding Structural Constituent Of Cytoskeleton Protein Binding Protein Kinase Binding Cell Adhesion Molecule Binding	Protein Binding Electron Carrier Activity Superoxide-generating NADPH Oxidase Activity SH3 Domain Binding Phosphatidylinositol Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	Movement Of Cell Or Subcellular Component Leukocyte Cell-cell Adhesion Positive Regulation Of Gene Expression Membrane To Membrane Docking Leukocyte Migration Establishment Of Endothelial Barrier Regulation Of Lymphocyte Migration	Response To Yeast Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Respiratory Burst Involved In Defense Response Protein Targeting To Membrane Leukotriene Metabolic Process Superoxide Metabolic Process Apoptotic Process Inflammatory Response Cellular Defense Response Cell Proliferation Superoxide Anion Generation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Innate Immune Response Respiratory Burst Negative Regulation Of Smooth Muscle Contraction Vascular Endothelial Growth Factor Receptor Signaling Pathway Hydrogen Peroxide Biosynthetic Process Interaction With Host Oxidation-reduction Process Neutrophil Mediated Killing Of Gram-positive Bacterium Neutrophil Mediated Killing Of Fungus Phagosome Maturation
Pathways		Axon guidance L1CAM interactions Recycling pathway of L1	Signaling by VEGF Phagosomal maturation (early endosomal stage) Latent infection of Homo sapiens with Mycobacterium tuberculosis Class I MHC mediated antigen processing & presentation Antigen processing-Cross presentation VEGFA-VEGFR2 Pathway Cross-presentation of particulate exogenous antigens (phagosomes) Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: BCAP31 CD44 CD46 CD93 CDK11B EZR ICAM1 ICAM2 ICAM3 L1CAM NCF1 NCF4 PLEC PPM1A PPM1B PRKCQ ROCK1 SELL SELPLG SLC9A3R1 SPN TERF1 TSC1 VCAM1	23 interactors: ACTB CSNK2B CYBA FASLG GAA GMNN KHDRBS1 MAPK9 MGAM MSN MYBPC1 MYBPC3 NCF4 NOXA1 PRKCA PRKCB PRKCD PRKCZ PRKDC SRSF2 SYTL1 TRAF4 TRIM9
Entrez ID		4478	653361
HPRD ID		02399
Ensembl ID		ENSG00000147065	ENSG00000158517
Uniprot IDs		P26038	P14598
PDB IDs		1E5W 1EF1 1SGH	1GD5 1K4U 1KQ6 1NG2 1O7K 1OV3 1UEC 1W70 1WLP
Enriched GO Terms of Interacting Partners?		Membrane To Membrane Docking Single Organismal Cell-cell Adhesion Cell Adhesion Leukocyte Migration Leukocyte Cell-cell Adhesion Leukocyte Tethering Or Rolling Positive Regulation Of Cell Adhesion Immune System Process Regulation Of Cell Adhesion Positive Regulation Of T Cell Proliferation Cellular Extravasation Membrane Docking Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Immune Response Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Cell-cell Adhesion Locomotion Regulation Of Immune System Process Regulation Of T Cell Proliferation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Movement Of Cell Or Subcellular Component Execution Phase Of Apoptosis Cell Migration Regulation Of Cell-cell Adhesion Cell Motility Positive Regulation Of T Cell Activation Cell Surface Receptor Signaling Pathway Immune Response Apoptotic Process Blood Coagulation Inflammatory Response Hemostasis Cell Activation Programmed Cell Death Cell Death Death Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Negative Regulation Of Signal Transduction Leukocyte Activation Interferon-gamma-mediated Signaling Pathway Response To Stimulus Regulation Of T Cell Activation Innate Immune Response Positive Regulation Of Cell Activation Negative Regulation Of Signaling Cellular Response To Interferon-gamma Regulation Of Body Fluid Levels	Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Insulin Receptor Signaling Pathway Regulation Of Insulin Receptor Signaling Pathway Regulation Of Cellular Response To Insulin Stimulus Histone H3-T6 Phosphorylation Platelet Activation Positive Regulation Of Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Catalytic Activity Positive Regulation Of Protein Metabolic Process Peptidyl-threonine Phosphorylation Immune System Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Body Fluid Levels Immune Response Apoptotic Signaling Pathway Apoptotic Process Regulation Of Catalytic Activity Programmed Cell Death Cell Activation Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Phospholipase Activity Cell Death Regulation Of Protein Phosphorylation Death Blood Coagulation Regulation Of Cellular Protein Metabolic Process Hemostasis Cell Surface Receptor Signaling Pathway Regulation Of Phospholipase Activity Cellular Response To Carbohydrate Stimulus Organelle Organization Mitotic Cell Cycle Positive Regulation Of Lipase Activity Response To Interleukin-1 Innate Immune Response Regulation Of Glucose Transport Regulation Of Platelet Aggregation Regulation Of Protein Metabolic Process Muscle System Process Negative Regulation Of Glucose Transport Signaling Regulation Of Phosphorylation Regulation Of Immune System Process Positive Regulation Of Immune System Process Positive Regulation Of Protein Modification Process Protein Phosphorylation Peptidyl-serine Phosphorylation
Tagcloud ?		assignments cen discordancy est00675 est00745 est00795 est00887 est00896 est01041 est01471 est01583 est01627 est01650 est01678 est01744 ests globule l18a l1a l1b moesin multiplexed s14 subregionally sulfurtransferase thiosulfate transhydrogenase xp11 xpter	anticancer atlas ccle computational consequences cosmic driver encyclopedia harboring identifying illustrated investigating mapped midostaurin nucleic onto plek pocket precision projects researchers rwdd1 somatic tcga tended tipifarnib uncover vav3 vinorelbine
Tagcloud (Difference) ?		assignments cen discordancy est00675 est00745 est00795 est00887 est00896 est01041 est01471 est01583 est01627 est01650 est01678 est01744 ests globule l18a l1a l1b moesin multiplexed s14 subregionally sulfurtransferase thiosulfate transhydrogenase xp11 xpter	anticancer atlas ccle computational consequences cosmic driver encyclopedia harboring identifying illustrated investigating mapped midostaurin nucleic onto plek pocket precision projects researchers rwdd1 somatic tcga tended tipifarnib uncover vav3 vinorelbine
Tagcloud (Intersection) ?