SPG7 and RBPMS

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SPG7	RBPMS
Gene Name		spastic paraplegia 7 (pure and complicated autosomal recessive)	RNA binding protein with multiple splicing
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Integral Component Of Membrane Mitochondrial Membrane	Nucleoplasm Cytoplasm
	Molecular Function	Metalloendopeptidase Activity Protein Binding ATP Binding Peptidase Activity Zinc Ion Binding Unfolded Protein Binding	Nucleotide Binding Transcription Coactivator Activity Protein Binding Poly(A) Binding Poly(A) RNA Binding
	Biological Process	Proteolysis Mitochondrion Organization Nervous System Development Anterograde Axon Cargo Transport	Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of SMAD Protein Import Into Nucleus
Pathways
Drugs
Diseases
GWAS			Heart rate variability traits ( 22174390)
Protein-Protein Interactions		23 interactors: CCNDBP1 HNRNPK KHDRBS2 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP4-12 LRIF1 LZTS2 MAPK6 MDFI MTUS2 NOTCH2NL PLSCR1 PNMA1 PSME3 PSTPIP1 RALY RBPMS SPATS1 STAMBP TRIM28	174 interactors: ADAM15 AES AMMECR1 APLN ARHGAP9 ARHGEF39 ARID5A ATN1 ATP6V0E2 ATXN1 BANP BBS2 BCL6B BHLHE40 BOLL C11orf87 C1orf111 C1orf94 C20orf195 C22orf39 C9orf24 CAMK2B CCER1 CCNG1 CCNK CDC23 CDC42EP1 CNNM3 CRBN CREB5 CRYBA1 CSN3 CSNK1G2-AS1 CYBA DAZAP2 DCAF8 DCDC2B DCTN5 DMRT3 DOK3 DOK6 DPYSL4 DTX2 DVL2 EFEMP2 ENKD1 EWSR1 EYA2 FAM103A1 FAM124B FAM168A FASTK FBF1 FBXL18 FOXC2 FOXP3 FOXS1 FXR2 GCM2 GLYCTK GPATCH2L GPS2 GRAP GRAP2 GSE1 HEY2 HEYL HNRNPLL HOXA1 HOXA9 HOXB9 IGF2 ILF3 INCA1 INIP IP6K2 KCTD9 KIF1A KIR2DL4 KPNA2 KRAS KRTAP12-2 KRTAP19-5 KRTAP19-7 KRTAP23-1 KRTAP8-1 LGALS9C LINC00482 LINC00588 LINC00908 LINC01547 LINC01588 LMO4 LOC142937 LOC148413 LONRF1 LRRC41 LRRC75A-AS1 LZTS2 MAGED1 MCM5 MGAT5B MVP MYOZ2 NAB2 NAPRT NEDD9 NEU4 NR1D2 NYNRIN OTX1 PAPD4 PDLIM4 PER1 PGLS PHF1 PIH1D1 PIN1 PITX1 PLAC8 POGZ POM121 PRKAA1 PRKAA2 PRKAB2 PRR20A QKI R3HDM2 RABL6 RBFOX1 RBFOX2 RDH12 RHOBTB3 RHOXF2 RIPPLY1 ROR2 RTP5 RUSC1 SBF2 SEMA4G SERF2 SF1 SH3RF2 SIRPB1 SMUG1 SNRPB SNRPC SPATA8 SPG7 STRBP TBX6 TEX37 TFG TIE1 TINAGL1 TMSB4X TOLLIP TOR1AIP2 TRIP13 TTLL10 TUSC2 VENTX VHL VHLL VPS37C WDR54 WDR90 WDYHV1 YPEL3 ZBTB32 ZC3H10 ZNF385C ZNF488 ZNF581
Entrez ID		6687	11030
HPRD ID		04149	11870
Ensembl ID		ENSG00000197912	ENSG00000157110
Uniprot IDs		Q9UQ90	B4E3T4 D3DSV0 Q93062
PDB IDs		2QZ4	1BNY
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Localization To Nucleus Regulation Of Protein Import Into Nucleus Negative Regulation Of Wnt Signaling Pathway Regulation Of Cellular Process Regulation Of Nucleocytoplasmic Transport Regulation Of Intracellular Protein Transport Gene Expression Regulation Of Wnt Signaling Pathway Negative Regulation Of Viral Process Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of DNA Demethylation Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Regulation Of Protein Localization Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Cytokinesis Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Embryonic Placenta Development Transcription, DNA-templated Inflammatory Response Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Regulation Of Intracellular Transport RNA Metabolic Process RNA Biosynthetic Process Convergent Extension Involved In Axis Elongation Regulation Of Genetic Imprinting Phosphatidylserine Biosynthetic Process DNA Methylation Involved In Embryo Development Regulation Of Cellular Localization Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Signal Transduction Regulation Of Viral Process Response To Stimulus Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Intracellular Protein Transport RNA Processing Negative Regulation Of Signaling Regulation Of Signal Transduction Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Receptor Biosynthetic Process Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Spindle Midzone Assembly Placenta Development Positive Regulation Of Protein Metabolic Process Phospholipid Scrambling Regulation Of Protein Transport	RNA Biosynthetic Process RNA Metabolic Process Transcription, DNA-templated Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Developmental Process Regulation Of Cellular Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Anatomical Structure Development Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Response To Stimulus Cellular Response To Stimulus Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Signaling Signal Transduction Cellular Metabolic Process Cell Communication Positive Regulation Of Macromolecule Biosynthetic Process System Development Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Anterior/posterior Pattern Specification Biosynthetic Process Regulation Of Circadian Rhythm Organ Development Insulin Receptor Signaling Pathway Cellular Process Response To Radiation
Tagcloud ?		ablated accumulates axons biogenesis corticospinal defines exposes hereditary implication isoform knock lacks limbs lumen microsomal name owing paraplegia paraplegin performs proteases recessive resides retina retrograde spastic spasticity usage weakness
Tagcloud (Difference) ?		ablated accumulates axons biogenesis corticospinal defines exposes hereditary implication isoform knock lacks limbs lumen microsomal name owing paraplegia paraplegin performs proteases recessive resides retina retrograde spastic spasticity usage weakness
Tagcloud (Intersection) ?