ZBTB7A and ZBTB48

Number of citations of the paper that reports this interaction (PubMedID 24382891)
41

Data Source:
BioGRID (affinity chromatography technology, pull down)

		ZBTB7A	ZBTB48
Description		zinc finger and BTB domain containing 7A	zinc finger and BTB domain containing 48
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Site Of Double-strand Break DNA-dependent Protein Kinase Complex	Chromosome, Telomeric Region Nucleus Chromosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Corepressor Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Histone Acetyltransferase Binding Sequence-specific DNA Binding SMAD Binding Metal Ion Binding Nuclear Androgen Receptor Binding DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Double-stranded Telomeric DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Glycolytic Process Chromatin Organization Chromatin Remodeling DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell Differentiation B Cell Differentiation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein Localization To Nucleus Regulation Of Apoptotic Process Erythrocyte Maturation Fat Cell Differentiation Negative Regulation Of Notch Signaling Pathway Negative Regulation Of DNA-templated Transcription Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Androgen Receptor Signaling Pathway Double-strand Break Repair Via Classical Nonhomologous End Joining Regulation Of Transcription Regulatory Region DNA Binding	Regulation Of Transcription By RNA Polymerase II Telomere Maintenance Via Telomere Lengthening Positive Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Chronic lymphocytic leukemia ( 28165464) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Pulse pressure ( 30578418) Reaction time ( 29844566) Red blood cell count ( 27863252 32888494)	Body size at age 10 ( 32376654)
Interacting Genes		25 interacting genes: BCL6 CRBN HOMEZ HSP90AA1 KHDRBS1 MBD3 NCOR1 NCOR2 OTUD4 PRKDC PSMD14 RELA SMAD4 SP1 SP3 SP4 TRIM25 UBE2I USP10 USP17L2 XRCC5 XRCC6 YBX1 ZBTB48 ZMYND8	35 interacting genes: C11orf58 CDK2AP2 CDKN1A CEP70 DVL2 DVL3 EP300 GPATCH2L ILK KRTAP1-1 KRTAP10-5 KRTAP10-7 L3MBTL2 LLCFC1 MAP1LC3A MCC NME7 PNRC2 RGS2 RNF10 SPANXN2 THAP1 TNFRSF14 TRIM41 TSPYL2 UPF2 WDR5 ZBTB26 ZBTB6 ZBTB7A ZBTB8A ZBTB9 ZNF317 ZNF408 ZNF837
Entrez ID		51341	3104
HPRD ID		10433	01316
Ensembl ID		ENSG00000178951	ENSG00000204859
Uniprot IDs		O95365	A8K291 B2R702 P10074
PDB IDs		2IF5 2NN2 7EYI 7N5S 7N5T 7N5U 7N5V 7N5W 8E3D 8E3E 8H9H	3B84 5YJ3
Enriched GO Terms of Interacting Partners?		Nucleus Regulation Of Primary Metabolic Process Nucleoplasm Regulation Of Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Macromolecule Metabolic Process Regulation Of RNA Biosynthetic Process Double-stranded DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II DNA Binding Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription Protein-DNA Complex Regulation Of Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process Negative Regulation Of RNA Metabolic Process DNA-dependent Protein Kinase Complex DNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein-containing Complex Transcription Cis-regulatory Region Binding DNA-dependent Protein Kinase-DNA Ligase 4 Complex Chromatin Regulation Of Innate Immune Response Nonhomologous End Joining Complex Positive Regulation Of Innate Immune Response Double-stranded Telomeric DNA Binding Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Telomere Maintenance Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Protein Metabolic Process Regulation Of Immune Response Activation Of Innate Immune Response Negative Regulation Of Biosynthetic Process Cellular Response To Stress Negative Regulation Of Metabolic Process DNA Recombination Telomere Organization Histone Deacetylase Binding Regulation Of Defense Response Double-strand Break Repair Via Nonhomologous End Joining Recombinational Repair Activation Of Immune Response Transcription Repressor Complex Positive Regulation Of Defense Response	Zinc Ion Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of DNA-templated Transcription Positive Regulation Of Neuron Projection Arborization Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Neuron Projection Arborization
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