PRR20A and ROR2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PRR20A	ROR2
Gene Name		proline rich 20A	receptor tyrosine kinase-like orphan receptor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Plasma Membrane Integral Component Of Plasma Membrane Clathrin-coated Endocytic Vesicle Membrane
	Molecular Function		Transmembrane Receptor Protein Tyrosine Kinase Activity Frizzled Binding Protein Binding ATP Binding Wnt-protein Binding
	Biological Process		Cartilage Condensation Somitogenesis Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Wnt Signaling Pathway, Calcium Modulating Pathway JNK Cascade Multicellular Organismal Development Negative Regulation Of Cell Proliferation Peptidyl-tyrosine Phosphorylation Cell Differentiation Positive Regulation Of Cell Migration Embryonic Genitalia Morphogenesis Inner Ear Morphogenesis Positive Regulation Of Transcription, DNA-templated Wnt Signaling Pathway, Planar Cell Polarity Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways			WNT5A-dependent internalization of FZD2, FZD5 and ROR2 Signaling by Wnt PCP/CE pathway beta-catenin independent WNT signaling
Drugs
Diseases
GWAS			Bipolar disorder and schizophrenia ( 22688191)
Protein-Protein Interactions		24 interactors: ATXN1 C1orf94 DAB1 DAZAP2 FAM168A FOXP3 GATA2 NAA38 NCK2 NEDD9 PITX1 POGZ RBFOX1 RBPMS ROR2 SELV SIAH1 SOX5 SP4 THAP1 TOLLIP VAC14 ZC3H10 ZNF488	13 interactors: C1orf94 CRX DAB1 DAZAP2 FZD2 FZD5 IKBKG MAGED1 MAP3K7 PRR20A RBPMS WNT5A ZMYM4
Entrez ID		122183	4920
HPRD ID		13445	03822
Ensembl ID		ENSG00000204919	ENSG00000169071
Uniprot IDs		P86478 P86479 P86480 P86481 P86496	Q01974
PDB IDs			3ZZW 4GT4
Enriched GO Terms of Interacting Partners?		Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Regulation Of Cellular Process Transcription, DNA-templated Regulation Of RNA Metabolic Process Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cell Differentiation Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Gene Expression Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cartilage Development Positive Regulation Of Cell Differentiation Anatomical Structure Development Regulation Of Histone Acetylation System Development Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Positive Regulation Of CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Positive Regulation Of Peripheral T Cell Tolerance Induction Pituitary Gland Development Central Nervous System Development Connective Tissue Development Ventral Spinal Cord Development Generation Of Neurons Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Cerebellum Structural Organization Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation Eosinophil Fate Commitment Cell Fate Commitment Neurogenesis Nervous System Development Developmental Process Negative Regulation Of Nucleic Acid-templated Transcription Neuron Differentiation Regulation Of Glial Cell Differentiation Negative Regulation Of RNA Biosynthetic Process	Positive Regulation Of Protein Phosphorylation Positive Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Kinase Activity Positive Regulation Of Protein Modification Process Positive Regulation Of MAP Kinase Activity Positive Regulation Of Kinase Activity Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transferase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of MAP Kinase Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Regulation Of Protein Kinase Activity Positive Regulation Of Metabolic Process Non-canonical Wnt Signaling Pathway Regulation Of Kinase Activity Positive Regulation Of MAPK Cascade Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Signal Transduction Regulation Of Cellular Protein Metabolic Process Regulation Of MAPK Cascade Regulation Of Signaling Positive Regulation Of JUN Kinase Activity Regulation Of JUN Kinase Activity Positive Regulation Of Transcription, DNA-templated Regulation Of Protein Metabolic Process JNK Cascade Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Canonical Wnt Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cytokine Production Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Catalytic Activity Positive Regulation Of Gene Expression Planar Cell Polarity Pathway Involved In Neural Tube Closure Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of JNK Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Regulation Of Intracellular Signal Transduction Anterior/posterior Axis Specification, Embryo
Tagcloud ?			alkaline alpi apical apicobasal applying border brush cathode coordinating created cue cytoskeleton determines electric electrical enterocytes erk1 ezrin faces lkb1 lumen mimic orienting polarity polarized polarizing remodeled stk11 transepithelial
Tagcloud (Difference) ?			alkaline alpi apical apicobasal applying border brush cathode coordinating created cue cytoskeleton determines electric electrical enterocytes erk1 ezrin faces lkb1 lumen mimic orienting polarity polarized polarizing remodeled stk11 transepithelial
Tagcloud (Intersection) ?