PRR20A and RBM42

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PRR20A	RBM42
Description		proline rich 20A	RNA binding motif protein 42
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm U4/U6 X U5 Tri-snRNP Complex
	Molecular Function		Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process		MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Cerebrospinal fluid t-tau:AB1-42 ratio ( 30153862) Left ventricular end-diastolic volume (MTAG) ( 33495596) Left ventricular end-systolic volume (MTAG) ( 33495596) Left ventricular mass (MTAG) ( 33495596) Systolic blood pressure ( 30224653) Total cholesterol levels ( 33339817)
Interacting Genes		95 interacting genes: ABI2 ANKHD1 ARID5A ATXN1 BANP BEND2 BHLHE40 BICRAL C10orf55 C1orf94 C3orf36 CABP2 CCNK CDC37 CELF4 DAB1 DAZAP2 DMRT3 DVL3 EIF4ENIF1 ESRP1 FAM168A FAM222B FAM9A FOXH1 FOXP3 GATA2 GLIS2 GTF2A1 HIVEP1 HLX HYPK KRTAP19-1 KRTAP19-5 LASP1 MAGED1 MBNL3 NAA38 NCK2 NEDD9 NOTCH3 NTAQ1 OXER1 PATZ1 PHF1 PITX1 POGZ POU6F2 PRR20B PRR20C PRR20D PRR20E PRR34 PRR35 PTTG2 RBFOX1 RBM10 RBM23 RBM42 RBPMS RBPMS2 RHOXF2 RIPPLY1 RNF4 ROR2 SAMD11 SELENOV SH3RF1 SMAP1 SNRPB SNRPC SOX5 SP4 SRPK2 TBX3 TBX6 TCF7L2 TFG THAP1 TIAL1 TLX3 TOLLIP TPRX1 TRIM35 VAC14 VENTX VEZF1 VPS37C YPEL3 ZBTB32 ZC3H10 ZCCHC14 ZNF385C ZNF488 ZNF683	23 interacting genes: APP BAG4 CEP55 DMRTB1 FHL3 HNRNPK OGT PCBP1 PPIL1 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBFOX2 RBM4 RBPMS RBPMS2 SFSWAP SNRPA TRNAU1AP WBP4
Entrez ID		122183	79171
HPRD ID		13445	11303
Ensembl ID		ENSG00000204919	ENSG00000126254
Uniprot IDs		P86478 P86479 P86480 P86481 P86496	Q9BTD8
PDB IDs			6QW6 6QX9 8H6E 8H6J 8QP8 8QP9 8QPK 8QXD 8R08 8R0A
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Transcription By RNA Polymerase II Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression DNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Splicing Regulation Of Macromolecule Metabolic Process Chromatin Protein Binding Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Processing Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Nucleic Acid Binding Positive Regulation Of Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Metabolic Process Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding Negative Regulation Of Biosynthetic Process RNA Splicing Sequence-specific DNA Binding Cell Fate Commitment Nucleoplasm MRNA Binding Myoblast Fate Commitment Regulation Of Neuron Differentiation Regulation Of Developmental Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Nucleic Acid Binding Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process RNA Splicing MRNA Binding MRNA Processing RNA Binding Cytoplasmic Stress Granule MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Metabolic Process RNA Metabolic Process Spliceosomal Complex Pre-mRNA Intronic Binding Regulation Of Translation Pre-mRNA Binding Nucleus Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Negative Regulation Of RNA Splicing MRNA 3'-UTR Binding Nucleic Acid Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Post-transcriptional Regulation Of Gene Expression MiRNA Binding Cap-independent Translational Initiation IRES-dependent Translational Initiation Of Linear MRNA Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Internal N(7)-methylguanine-containing RNA Reader Activity Negative Regulation Of MRNA Modification Negative Regulation Of Translational Initiation Negative Regulation Of RNA Metabolic Process Negative Regulation Of Translation
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