SRSF5 and OLFM2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SRSF5	OLFM2
Gene Name		serine/arginine-rich splicing factor 5	olfactomedin 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Nuclear Speck	Extracellular Region Cell Junction Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Selective Glutamate Receptor Complex Synapse
	Molecular Function	Nucleotide Binding Protein Binding Poly(A) RNA Binding RS Domain Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Splice Site Selection MRNA Processing MRNA Export From Nucleus RNA Splicing Response To Wounding Gene Expression MRNA 3'-end Processing Regulation Of Cell Cycle	Protein Secretion
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS			Menarche (age at onset) ( 21102462)
Protein-Protein Interactions		16 interactors: CALM1 CD101 DYRK1A HIPK3 MAPK14 MAPK6 OLFM2 PPARGC1A RPS6KA1 SMURF1 SNRPF SREK1 SRPK1 SRPK2 SRSF1 TNK2	11 interactors: BLOC1S6 EIF1 FANCF GNB5 KRTAP10-3 NBAS PKM ROBO2 RPS6 SRSF5 ST13
Entrez ID		6430	93145
HPRD ID		02948	10127
Ensembl ID		ENSG00000100650	ENSG00000105088
Uniprot IDs		Q13243 Q86U32	K7EIS8 O95897
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Processing Regulation Of RNA Splicing Protein Phosphorylation Phosphorylation MRNA Metabolic Process RNA Processing Innate Immune Response Regulation Of Cellular Protein Metabolic Process Phosphate-containing Compound Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Peptidyl-serine Phosphorylation Cellular Protein Modification Process Positive Regulation Of Viral Genome Replication Intracellular Signal Transduction Glucose Metabolic Process Immune Response Defense Response Posttranscriptional Regulation Of Gene Expression Ribonucleoprotein Complex Assembly Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Cellular Metabolic Process Termination Of RNA Polymerase II Transcription Hexose Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Peptidyl-threonine Phosphorylation MAPK Cascade Negative Regulation Of Viral Genome Replication MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Cellular Response To Growth Factor Stimulus Signal Transduction Monosaccharide Metabolic Process Regulation Of MRNA Stability Response To Growth Factor Toll-like Receptor 5 Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of RNA Stability Toll-like Receptor 10 Signaling Pathway Cellular Protein Metabolic Process Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Nuclear Speck Organization P38MAPK Cascade	Ovulation Cycle Process Negative Regulation Of Negative Chemotaxis Female Gonad Development Reproductive Structure Development Reproductive System Development Ovulation Cycle Development Of Primary Female Sexual Characteristics MRNA Metabolic Process Apoptotic Process Involved In Luteolysis Negative Regulation Of Protein Refolding Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Negative Chemotaxis Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Axon Midline Choice Point Recognition Chaperone Cofactor-dependent Protein Refolding Luteolysis Ribonucleoprotein Complex Assembly Negative Regulation Of Voltage-gated Calcium Channel Activity Oogenesis Stage Activation-induced Cell Death Of T Cells Secretion Of Lysosomal Enzymes Intracellular Transport Cytoplasmic Transport RNA Catabolic Process Axon Choice Point Recognition Developmental Process Involved In Reproduction Pigment Granule Maturation Synaptic Vesicle Docking Endosome To Melanosome Transport Multicellular Organismal Reproductive Process Olfactory Bulb Interneuron Development T Cell Proliferation Involved In Immune Response Gonad Development Translational Initiation Development Of Primary Sexual Characteristics Cellular Pigment Accumulation Multicellular Organism Reproduction Ribosomal Small Subunit Assembly Dosage Compensation By Inactivation Of X Chromosome Golgi Vesicle Transport Dosage Compensation Positive Regulation Of Pigment Cell Differentiation
Tagcloud ?		a014418 antiapoptotic anxa7 ar bcl2 bmi1 deregulation downregulating downregulation escape factual glioblastoma glycogen gsk3 gsk3alpha gsk3beta hnrnp manzamine mcl1 posttreatment ptpb1 reflected splicing srsf1 tyr u373 u87 va xl
Tagcloud (Difference) ?		a014418 antiapoptotic anxa7 ar bcl2 bmi1 deregulation downregulating downregulation escape factual glioblastoma glycogen gsk3 gsk3alpha gsk3beta hnrnp manzamine mcl1 posttreatment ptpb1 reflected splicing srsf1 tyr u373 u87 va xl
Tagcloud (Intersection) ?