SLC16A2 and MFSD6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC16A2	MFSD6
Description		solute carrier family 16 member 2	major facilitator superfamily domain containing 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Apical Plasma Membrane	Plasma Membrane Membrane
	Molecular Function	Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Thyroid Hormone Transmembrane Transporter Activity Transmembrane Transporter Activity Identical Protein Binding Carboxylic Acid Transmembrane Transporter Activity	Protein Binding
	Biological Process	Amino Acid Metabolic Process Thyroid Hormone Generation Monocarboxylic Acid Transport Thyroid Hormone Metabolic Process Transmembrane Transport Thyroid Hormone Transport Thyroid-stimulating Hormone Secretion Amino Acid Import Across Plasma Membrane Transport Across Blood-brain Barrier Carboxylic Acid Transmembrane Transport Negative Regulation Of Neural Precursor Cell Proliferation	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Pathways		Organic anion transport by SLCO transporters
Drugs		Pyruvic acid
Diseases		Allan-Herndon-Dudley syndrome; Monocarboxylate transporter 8 deficiency
GWAS			Arthritis (juvenile idiopathic) ( 33106285) Daytime sleep phenotypes ( 27126917) Estimated glomerular filtration rate ( 31015462) Medication use (thyroid preparations) ( 31015401) Platelet count ( 32888494)
Interacting Genes		38 interacting genes: ADIPOQ ANKRD46 APOL3 BTN2A2 C3orf52 CCL2 CNIH3 COL4A5 CXCL16 CYB5B EFNA5 FAM3C JAGN1 LAT LEPROTL1 LHFPL5 LPAR3 MFSD6 MS4A13 PLP1 PNLIPRP1 SERPINA7 SLC30A2 SLC38A7 SLC39A13 SLC39A9 SMCO4 SYNGR1 THRA TMEM254 TMEM60 TOMM6 TRARG1 TSPO2 UNC93B1 UPK1B VAMP3 VEGFA	37 interacting genes: ADIPOQ ALG8 APH1A APOL3 AQP7 C19orf18 CD79A CYB5R3 EBP ERGIC3 FAM209A GJA8 GJB2 GPR152 GPR42 GPX8 LY6E NKG7 PDCD1LG2 SELENOK SGPL1 SHISAL1 SLC10A1 SLC10A6 SLC16A2 SLC18A1 SLC39A2 SLC60A2 SMIM1 SSMEM1 STX12 SYNDIG1 TMEM179B TMEM237 TMEM242 TMEM258 TSPO2
Entrez ID		6567	54842
HPRD ID		02106	13369
Ensembl ID		ENSG00000147100	ENSG00000151690
Uniprot IDs		P36021	B7Z7Y2 Q6ZSS7
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Zinc Ion Transport Zinc Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport Intracellular Zinc Ion Homeostasis Cytokine Activity Neutrophil Differentiation Myeloid Cell Differentiation Positive Regulation Of Collateral Sprouting Regulation Of Protein Autophosphorylation Positive Regulation Of Cell Growth	Membrane Organic Hydroxy Compound Transport Bile Acid:sodium Symporter Activity Gap Junction-mediated Intercellular Transport
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