MFSD6 and AQP7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MFSD6	AQP7
Description		major facilitator superfamily domain containing 6	aquaporin 7
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Cytoplasm Lipid Droplet Plasma Membrane Cell-cell Junction Membrane Basolateral Plasma Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity Channel Activity
	Biological Process	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I	Water Transport Glycerol Transmembrane Transport Transmembrane Transport Urea Transmembrane Transport
Pathways			Transport of glycerol from adipocytes to the liver by Aquaporins Passive transport by Aquaporins
Drugs
Diseases
GWAS		Arthritis (juvenile idiopathic) ( 33106285) Daytime sleep phenotypes ( 27126917) Estimated glomerular filtration rate ( 31015462) Medication use (thyroid preparations) ( 31015401) Platelet count ( 32888494)	Lung adenocarcinoma ( 28604730) Urinary albumin excretion ( 30220432)
Interacting Genes		37 interacting genes: ADIPOQ ALG8 APH1A APOL3 AQP7 C19orf18 CD79A CYB5R3 EBP ERGIC3 FAM209A GJA8 GJB2 GPR152 GPR42 GPX8 LY6E NKG7 PDCD1LG2 SELENOK SGPL1 SHISAL1 SLC10A1 SLC10A6 SLC16A2 SLC18A1 SLC39A2 SLC60A2 SMIM1 SSMEM1 STX12 SYNDIG1 TMEM179B TMEM237 TMEM242 TMEM258 TSPO2	4 interacting genes: ABHD16A CLCN7 COMT MFSD6
Entrez ID		54842	364
HPRD ID		13369	04277
Ensembl ID		ENSG00000151690	ENSG00000165269
Uniprot IDs		B7Z7Y2 Q6ZSS7	B7Z4U2 O14520 Q5T5M0 Q6P5T0
PDB IDs			6KXW 6N1G 6QZI 6QZJ 8AMW 8AMX 8C9H
Enriched GO Terms of Interacting Partners?		Membrane Organic Hydroxy Compound Transport Bile Acid:sodium Symporter Activity Gap Junction-mediated Intercellular Transport	Chloride:proton Antiporter Activity Cellular Response To Phosphate Starvation Norepinephrine Secretion Catechol O-methyltransferase Activity Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Transepithelial Chloride Transport O-methyltransferase Activity Renal Tubular Secretion Dopamine Secretion Habituation Renal Protein Absorption Mastication Catecholamine Catabolic Process Renal Sodium Excretion Renal Albumin Absorption Norepinephrine Transport Nonassociative Learning Renin Secretion Into Blood Stream Cellular Response To Cocaine Response To Dopamine Dopamine Catabolic Process Catecholamine Secretion Cerebellar Cortex Morphogenesis Monoacylglycerol Catabolic Process Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Monoacylglycerol Lipase Activity Synaptic Transmission, Dopaminergic Glomerulus Development Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Norepinephrine Metabolic Process Startle Response Response To Corticosterone Phosphatidylserine Metabolic Process Chloride Transmembrane Transporter Activity Renal Filtration Dopamine Transport Response To Catecholamine Detection Of Temperature Stimulus Involved In Sensory Perception Phosphatidylcholine Lysophospholipase Activity Detection Of Temperature Stimulus Response To Salt Glycerophospholipid Catabolic Process Response To Angiotensin Phospholipase Activity Acylglycerol Catabolic Process Cholesterol Efflux Monoamine Transport Dopamine Metabolic Process
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