SLC16A2 and SLC39A13

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC16A2	SLC39A13
Description		solute carrier family 16 member 2	solute carrier family 39 member 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Apical Plasma Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Thyroid Hormone Transmembrane Transporter Activity Transmembrane Transporter Activity Identical Protein Binding Carboxylic Acid Transmembrane Transporter Activity	Zinc Ion Transmembrane Transporter Activity Protein Binding Protein Homodimerization Activity Metal Ion Transmembrane Transporter Activity
	Biological Process	Amino Acid Metabolic Process Thyroid Hormone Generation Monocarboxylic Acid Transport Thyroid Hormone Metabolic Process Transmembrane Transport Thyroid Hormone Transport Thyroid-stimulating Hormone Secretion Amino Acid Import Across Plasma Membrane Transport Across Blood-brain Barrier Carboxylic Acid Transmembrane Transport Negative Regulation Of Neural Precursor Cell Proliferation	Monoatomic Ion Transport Zinc Ion Transport Intracellular Zinc Ion Homeostasis Metal Ion Transport Brown Fat Cell Differentiation Transmembrane Transport Connective Tissue Development Zinc Ion Transmembrane Transport
Pathways		Organic anion transport by SLCO transporters
Drugs		Pyruvic acid
Diseases		Allan-Herndon-Dudley syndrome; Monocarboxylate transporter 8 deficiency	Ehlers-Danlos syndrome (EDS), including: EDS classical type (EDS1/2); EDS hypermobility type (EDS3); EDS vascular type (EDS4); EDS kyphoscoliosis type (EDS6); EDS arthrochalasia type (EDS7A/7B); EDS dermatospraxis type (EDS7C); EDS autosomal recessive cardiac valvular form (EDSCV); EDS musculocontractural type (EDSMC); EDS progeroid form (EDSP); Tenascin-X deficiency (TNXD); Brittle cornea syndrome (EDS6B); EDS-like spondylocheiro dysplasia (SCD-EDS)
GWAS			Alcohol use disorder (total score) ( 30336701) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Blood urea nitrogen levels ( 31152163) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic kidney disease ( 31152163) Diastolic blood pressure ( 27618452 28739976) Estimated glomerular filtration rate ( 31152163 31015462) Fruit consumption ( 32066663) Global electrical heterogeneity phenotypes ( 29622589) Hip circumference ( 25673412) Lacunar stroke ( 33773637) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Neuroticism ( 29255261) Problematic alcohol use ( 32451486) Refractive error ( 32231278) Systolic blood pressure ( 30578418 28739976 27618452) Waist circumference ( 25673412)
Interacting Genes		38 interacting genes: ADIPOQ ANKRD46 APOL3 BTN2A2 C3orf52 CCL2 CNIH3 COL4A5 CXCL16 CYB5B EFNA5 FAM3C JAGN1 LAT LEPROTL1 LHFPL5 LPAR3 MFSD6 MS4A13 PLP1 PNLIPRP1 SERPINA7 SLC30A2 SLC38A7 SLC39A13 SLC39A9 SMCO4 SYNGR1 THRA TMEM254 TMEM60 TOMM6 TRARG1 TSPO2 UNC93B1 UPK1B VAMP3 VEGFA	9 interacting genes: CD40 CREB3 F2RL1 MAPK8IP2 OPRM1 PGRMC2 REL SLC16A2 TCF4
Entrez ID		6567	91252
HPRD ID		02106	12287
Ensembl ID		ENSG00000147100	ENSG00000165915
Uniprot IDs		P36021	G3V1B2 Q96H72
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Zinc Ion Transport Zinc Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport Intracellular Zinc Ion Homeostasis Cytokine Activity Neutrophil Differentiation Myeloid Cell Differentiation Positive Regulation Of Collateral Sprouting Regulation Of Protein Autophosphorylation Positive Regulation Of Cell Growth	Positive Regulation Of MAPK Cascade Positive Regulation Of Positive Chemotaxis G-protein Alpha-subunit Binding G-protein Beta-subunit Binding Positive Regulation Of Intracellular Signal Transduction Regulation Of Intracellular Signal Transduction Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MAPK Cascade Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Renin Secretion Into Blood Stream Morphine Receptor Activity Negative Regulation Of Wnt Protein Secretion Beta-endorphin Receptor Activity Positive Regulation Of Deacetylase Activity Positive Regulation Of Signal Transduction Intracellular Signaling Cassette Negative Regulation Of Protein Secretion Neuronal Cell Body Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Cell Communication Regulation Of Signal Transduction Signal Transduction Positive Regulation Of Interleukin-4-mediated Signaling Pathway Positive Regulation Of Protein Kinase C Signaling Intracellular Signal Transduction Positive Regulation Of Signaling Response To Cobalamin Positive Regulation Of RNA Metabolic Process Proteinase-activated Receptor Activity Positive Regulation Of Glomerular Filtration Regulation Of Renin Secretion Into Blood Stream Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Eosinophil Degranulation Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Cellular Response To Morphine DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Thyroid-stimulating Hormone Secretion Beta-catenin-TCF7L2 Complex Regulation Of Protein Kinase C Signaling Positive Regulation Of Cell Migration Leukocyte Proliferation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Response To Erythropoietin Inflammatory Response Cellular Response To Erythropoietin Negative Regulation Of Secretion By Cell
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?