SLC16A2 and CXCL16

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC16A2	CXCL16
Description		solute carrier family 16 member 2	C-X-C motif chemokine ligand 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Apical Plasma Membrane	Extracellular Region Extracellular Space Plasma Membrane Membrane
	Molecular Function	Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Thyroid Hormone Transmembrane Transporter Activity Transmembrane Transporter Activity Identical Protein Binding Carboxylic Acid Transmembrane Transporter Activity	Low-density Lipoprotein Particle Receptor Activity Scavenger Receptor Activity Cytokine Activity Chemokine Activity
	Biological Process	Amino Acid Metabolic Process Thyroid Hormone Generation Monocarboxylic Acid Transport Thyroid Hormone Metabolic Process Transmembrane Transport Thyroid Hormone Transport Thyroid-stimulating Hormone Secretion Amino Acid Import Across Plasma Membrane Transport Across Blood-brain Barrier Carboxylic Acid Transmembrane Transport Negative Regulation Of Neural Precursor Cell Proliferation	Receptor-mediated Endocytosis Chemotaxis Signal Transduction T Cell Chemotaxis Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Response To Cytokine Response To Type II Interferon Response To Tumor Necrosis Factor Lymphocyte Chemotaxis
Pathways		Organic anion transport by SLCO transporters	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs		Pyruvic acid
Diseases		Allan-Herndon-Dudley syndrome; Monocarboxylate transporter 8 deficiency
GWAS			Blood protein levels ( 30072576) Blood protein levels in cardiovascular risk ( 28369058)
Interacting Genes		38 interacting genes: ADIPOQ ANKRD46 APOL3 BTN2A2 C3orf52 CCL2 CNIH3 COL4A5 CXCL16 CYB5B EFNA5 FAM3C JAGN1 LAT LEPROTL1 LHFPL5 LPAR3 MFSD6 MS4A13 PLP1 PNLIPRP1 SERPINA7 SLC30A2 SLC38A7 SLC39A13 SLC39A9 SMCO4 SYNGR1 THRA TMEM254 TMEM60 TOMM6 TRARG1 TSPO2 UNC93B1 UPK1B VAMP3 VEGFA	66 interacting genes: ADAMTSL4 APP AQP2 AQP6 AQP9 ARL13B ATP6V0E1 BIK CARD10 CCDC70 CD53 CERS4 CLDN7 CREB3L1 CXCR6 CYSRT1 FAM209A FFAR2 FKBP7 FNDC9 GJA8 GORAB GPR42 GPX8 HHATL HOXA1 KASH5 KIR2DL3 KRT31 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP5-9 LHFPL5 LMNA MDFI MFF MTUS2 MUC1 NBPF19 NEMP1 NOTCH2NLA PEX12 SAR1A SLC10A6 SLC16A2 SLC18A1 SLC39A1 SNCA SPN SSMEM1 STX1A TGM1 TLCD4 TMEM139 TMEM14B TMEM237 TMEM239 TMEM35A TMX2 TSPAN12
Entrez ID		6567	58191
HPRD ID		02106	16103
Ensembl ID		ENSG00000147100	ENSG00000161921
Uniprot IDs		P36021	Q9H2A7
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Zinc Ion Transport Zinc Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport Intracellular Zinc Ion Homeostasis Cytokine Activity Neutrophil Differentiation Myeloid Cell Differentiation Positive Regulation Of Collateral Sprouting Regulation Of Protein Autophosphorylation Positive Regulation Of Cell Growth	Intermediate Filament Keratin Filament Membrane Water Channel Activity Identical Protein Binding Cellular Response To Copper Ion Water Transport
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