NCF1 and MYBPC1

Number of citations of the paper that reports this interaction (PMID 16052631)
27

Data Source:
BioGRID (two hybrid)

		NCF1	MYBPC1
Gene Name		neutrophil cytosolic factor 1	myosin binding protein C, slow type
Image
Gene Ontology Annotations	Cellular Component	Rough Endoplasmic Reticulum Golgi Apparatus Cytosol Extrinsic Component Of Membrane Dendrite Phagolysosome NADPH Oxidase Complex Neuronal Cell Body	Cytosol Myofibril Myosin Filament
	Molecular Function	Protein Binding Electron Carrier Activity Superoxide-generating NADPH Oxidase Activity SH3 Domain Binding Phosphatidylinositol Binding Phosphatidylinositol-3,4-bisphosphate Binding	Actin Binding Protein Binding Structural Constituent Of Muscle Titin Binding
	Biological Process	Response To Yeast Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Respiratory Burst Involved In Defense Response Protein Targeting To Membrane Leukotriene Metabolic Process Superoxide Metabolic Process Apoptotic Process Inflammatory Response Cellular Defense Response Cell Proliferation Superoxide Anion Generation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Innate Immune Response Respiratory Burst Negative Regulation Of Smooth Muscle Contraction Vascular Endothelial Growth Factor Receptor Signaling Pathway Hydrogen Peroxide Biosynthetic Process Interaction With Host Oxidation-reduction Process Neutrophil Mediated Killing Of Gram-positive Bacterium Neutrophil Mediated Killing Of Fungus Phagosome Maturation	Cell Adhesion Muscle Filament Sliding
Pathways		Signaling by VEGF Phagosomal maturation (early endosomal stage) Latent infection of Homo sapiens with Mycobacterium tuberculosis Class I MHC mediated antigen processing & presentation Antigen processing-Cross presentation VEGFA-VEGFR2 Pathway Cross-presentation of particulate exogenous antigens (phagosomes) Adaptive Immune System	Striated Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: ACTB CSNK2B CYBA FASLG GAA GMNN KHDRBS1 MAPK9 MGAM MSN MYBPC1 MYBPC3 NCF4 NOXA1 PRKCA PRKCB PRKCD PRKCZ PRKDC SRSF2 SYTL1 TRAF4 TRIM9	10 interactors: CALM1 FHL1 FHL2 FHL3 MEOX2 NCF1 RAF1 TRIM55 TRIM63 TTN
Entrez ID		653361	4604
HPRD ID			01185
Ensembl ID		ENSG00000158517	ENSG00000196091
Uniprot IDs		P14598	A8KAB1 B3KPP3 Q00872 Q86TA8
PDB IDs		1GD5 1K4U 1KQ6 1NG2 1O7K 1OV3 1UEC 1W70 1WLP	1X44 2DAV 2YUV 2YUW 2YUX 2YUZ 2YXM
Enriched GO Terms of Interacting Partners?		Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Insulin Receptor Signaling Pathway Regulation Of Insulin Receptor Signaling Pathway Regulation Of Cellular Response To Insulin Stimulus Histone H3-T6 Phosphorylation Platelet Activation Positive Regulation Of Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Catalytic Activity Positive Regulation Of Protein Metabolic Process Peptidyl-threonine Phosphorylation Immune System Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Body Fluid Levels Immune Response Apoptotic Signaling Pathway Apoptotic Process Regulation Of Catalytic Activity Programmed Cell Death Cell Activation Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Phospholipase Activity Cell Death Regulation Of Protein Phosphorylation Death Blood Coagulation Regulation Of Cellular Protein Metabolic Process Hemostasis Cell Surface Receptor Signaling Pathway Regulation Of Phospholipase Activity Cellular Response To Carbohydrate Stimulus Organelle Organization Mitotic Cell Cycle Positive Regulation Of Lipase Activity Response To Interleukin-1 Innate Immune Response Regulation Of Glucose Transport Regulation Of Platelet Aggregation Regulation Of Protein Metabolic Process Muscle System Process Negative Regulation Of Glucose Transport Signaling Regulation Of Phosphorylation Regulation Of Immune System Process Positive Regulation Of Immune System Process Positive Regulation Of Protein Modification Process Protein Phosphorylation Peptidyl-serine Phosphorylation	Muscle Structure Development Muscle Organ Development Vascular Endothelial Growth Factor Receptor Signaling Pathway Organ Development Activation Of Adenylate Cyclase Activity Platelet Activation Muscle Contraction Positive Regulation Of Adenylate Cyclase Activity Muscle System Process Positive Regulation Of Lyase Activity Regulation Of Adenylate Cyclase Activity Striated Muscle Tissue Development Positive Regulation Of CAMP Biosynthetic Process Muscle Tissue Development Cardiovascular System Development Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Cardiac Muscle Cell Development System Development Platelet Degranulation Response To Hormone Death-inducing Signaling Complex Assembly Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Blood Coagulation Hemostasis Response To Abiotic Stimulus Regulation Of CAMP Metabolic Process Neutrophil Mediated Killing Of Gram-positive Bacterium Neutrophil Mediated Killing Of Fungus Multicellular Organismal Development Cardiac Muscle Cell Differentiation Reactive Oxygen Species Metabolic Process Anatomical Structure Development Heart Development Response To Calcium Ion Skeletal Muscle Myosin Thick Filament Assembly Atrial Cardiac Muscle Cell Development Sarcomerogenesis Detection Of Muscle Stretch Cardiocyte Differentiation Regulation Of Body Fluid Levels Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Directional Locomotion Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Wound Healing Anatomical Structure Morphogenesis Response To Glucocorticoid
Tagcloud ?		anticancer atlas ccle computational consequences cosmic driver encyclopedia harboring identifying illustrated investigating mapped midostaurin nucleic onto plek pocket precision projects researchers rwdd1 somatic tcga tended tipifarnib uncover vav3 vinorelbine	ankrd2 annotation besides breed breeds dctn1 deg duroc est explaining giving grouped helpful libraries listed meat myl2 myogenesis neb novels piau pig postnatal prenatal prenatally tags transcriptome uncovering vertebrates
Tagcloud (Difference) ?		anticancer atlas ccle computational consequences cosmic driver encyclopedia harboring identifying illustrated investigating mapped midostaurin nucleic onto plek pocket precision projects researchers rwdd1 somatic tcga tended tipifarnib uncover vav3 vinorelbine	ankrd2 annotation besides breed breeds dctn1 deg duroc est explaining giving grouped helpful libraries listed meat myl2 myogenesis neb novels piau pig postnatal prenatal prenatally tags transcriptome uncovering vertebrates
Tagcloud (Intersection) ?