Wiki-Pi
About
Search
People
Updates
Search
NCF1 and MYBPC1
Number of citations of the paper that reports this interaction (PubMedID
16052631
)
0
Data Source:
BioGRID
(two hybrid)
NCF1
MYBPC1
Description
neutrophil cytosolic factor 1
myosin binding protein C1
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
Cytoplasmic Side Of Plasma Membrane
Membrane
Dendrite
Phagolysosome
NADPH Oxidase Complex
Neuronal Cell Body
Cytosol
Myofibril
M Band
Myosin Filament
Molecular Function
Protein Binding
Lipid Binding
Electron Transfer Activity
Superoxide-generating NAD(P)H Oxidase Activity
Superoxide-generating NADPH Oxidase Activator Activity
SH3 Domain Binding
Phosphatidylinositol Binding
Phosphatidylinositol-3,4-bisphosphate Binding
Actin Binding
Protein Binding
Structural Constituent Of Muscle
Myosin Binding
Titin Binding
Biological Process
Response To Yeast
Leukocyte Mediated Cytotoxicity
Respiratory Burst Involved In Defense Response
Protein Targeting To Membrane
Leukotriene Metabolic Process
Superoxide Metabolic Process
Inflammatory Response
Cellular Defense Response
Response To Bacterium
Superoxide Anion Generation
Defense Response To Bacterium
Innate Immune Response
Respiratory Burst
Hydrogen Peroxide Biosynthetic Process
Epithelial Cell Proliferation
Defense Response To Gram-positive Bacterium
Defense Response To Fungus
Regulation Of Respiratory Burst Involved In Inflammatory Response
Neutrophil-mediated Killing Of Gram-positive Bacterium
Neutrophil-mediated Killing Of Fungus
Cellular Response To Glucose Stimulus
Cellular Response To Testosterone Stimulus
Reactive Oxygen Species Metabolic Process
Reactive Oxygen Species Biosynthetic Process
Cell Adhesion
Sarcomere Organization
Pathways
ROS and RNS production in phagocytes
Cross-presentation of particulate exogenous antigens (phagosomes)
Detoxification of Reactive Oxygen Species
VEGFA-VEGFR2 Pathway
RHO GTPases Activate NADPH Oxidases
RAC1 GTPase cycle
RAC2 GTPase cycle
RAC3 GTPase cycle
Striated Muscle Contraction
Drugs
Dextromethorphan
Diseases
Chronic granulomatous disease, including the following four diseases: X-linked CGD (gp91 phox CGD); p22phox deficiency (p22phox CGD); p47phox deficiency (p47phox CGD); p67phox deficiency (p67phox CGD)
GWAS
Systemic lupus erythematosus (
33493351
)
Lung function (FEV1) (
24023788
)
Memory decline (
31985465
)
Interacting Genes
29 interacting genes:
ACTB
CEBPA
CSNK2B
FASLG
GAA
GMNN
KHDRBS1
MAPK9
MGAM
MSN
MYBPC1
MYBPC3
NCF2
NCF4
NOXA1
PKD1
PLA2G4A
PRKCA
PRKCB
PRKCD
PRKCZ
PRKDC
PTEN
RB1
SH3RF1
SRSF2
SYTL1
TRAF4
TRIM9
27 interacting genes:
ACO1
AMOT
ANKRD1
ASH2L
C1QTNF9
CALM1
CAPN3
CLIP4
DNAJB5
DNAJB6
DYSF
FHL1
FHL2
FHL3
GABARAP
GABARAPL1
GABARAPL2
KLHL41
MAP1LC3A
MEOX2
MYBPC2
NCF1
RAF1
SGCG
TRIM55
TRIM63
TTN
Entrez ID
653361
4604
HPRD ID
01185
Ensembl ID
ENSG00000158517
ENSG00000196091
Uniprot IDs
P14598
A8KAB1
B3KPP3
Q00872
PDB IDs
1GD5
1K4U
1KQ6
1NG2
1O7K
1OV3
1UEC
1W70
1WLP
7YXW
8WEJ
1X44
2DAV
2YUV
2YUW
2YUX
2YUZ
2YXM
Enriched GO Terms of Interacting Partners
?
Diacylglycerol-dependent Serine/threonine Kinase Activity
Protein Kinase C Signaling
Enzyme Binding
Superoxide-generating NADPH Oxidase Activator Activity
Regulation Of Immune System Process
Cytosol
Protein Phosphorylation
Protein Domain Specific Binding
Regulation Of Protein Metabolic Process
Phosphorylation
Maltose Metabolic Process
NADPH Oxidase Complex
Histone H3T6 Kinase Activity
Positive Regulation Of Immune System Process
Protein Serine/threonine Kinase Activity
Regulation Of Hemopoiesis
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Peptidyl-threonine Phosphorylation
Regulation Of Cell Activation
Alpha-1,4-glucosidase Activity
Superoxide Anion Generation
Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity
Regulation Of Apoptotic Process
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Programmed Cell Death
Regulation Of Mitotic Cell Cycle
Positive Regulation Of Leukocyte Differentiation
Alpha-glucosidase Activity
Phagolysosome
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Multicellular Organismal Process
Protein Serine Kinase Activity
Rb-E2F Complex
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Catabolic Process
PML Body
Regulation Of Proteolysis
Regulation Of Primary Metabolic Process
Regulation Of Cell Cycle
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Transport
Regulation Of Cell Development
Superoxide Metabolic Process
Plasma Membrane
Extracellular Exosome
Response To Hormone
Nuclear Matrix
Regulation Of Multicellular Organismal Development
Cellular Response To Nitrogen Starvation
Titin Binding
Phosphatidylethanolamine Binding
Actin Cytoskeleton Organization
Z Disc
M Band
Cytoskeleton Organization
Actin Filament-based Process
Sarcomere Organization
Actomyosin Structure Organization
Autophagosome Maturation
Phospholipid Binding
Autophagosome Membrane
Mitophagy
GABA Receptor Binding
Autophagy Of Mitochondrion
Organelle Organization
Autophagosome
Response To Muscle Stretch
Myofibril Assembly
Autophagosome Assembly
Autophagosome Organization
Adenylate Cyclase Activator Activity
Beta-tubulin Binding
Structural Constituent Of Muscle
Muscle Organ Development
Response To Iron(II) Ion
Muscle Structure Development
Protein-containing Complex Disassembly
Organelle Assembly
Cytoplasm
Macroautophagy
Response To Metal Ion
Vacuole Organization
Microtubule
Cellular Response To Starvation
Pseudopodium
Response To Starvation
Cellular Response To Nutrient Levels
Cytosol
I Band
Supramolecular Fiber Organization
Response To Iron Ion
Autophagy
Response To Calcium Ion
Ubiquitin Protein Ligase Binding
Anatomical Structure Formation Involved In Morphogenesis
Protein Binding
Calcium-dependent Self Proteolysis
Monocyte Activation Involved In Immune Response
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?