SLC2A5 and USP40

Number of citations of the paper that reports this interaction (PubMedID 35605301)
0

Data Source:
BioGRID (two hybrid)

		SLC2A5	USP40
Description		solute carrier family 2 member 5	ubiquitin specific peptidase 40
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Apical Plasma Membrane Specific Granule Membrane Sarcolemma Extracellular Exosome	Nucleus Cytosol
	Molecular Function	Fructose Transmembrane Transporter Activity Protein Binding Transmembrane Transporter Activity D-glucose Transmembrane Transporter Activity Fructose Binding	Cysteine-type Deubiquitinase Activity Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity
	Biological Process	Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Carbohydrate Metabolic Process Response To Fructose Fructose Transmembrane Transport D-glucose Import Transmembrane Transport Dehydroascorbic Acid Transport Cellular Response To Fructose Stimulus Intestinal Hexose Absorption D-glucose Transmembrane Transport Fructose Import Across Plasma Membrane	Proteolysis Protein Deubiquitination Regulation Of Protein Stability
Pathways		Neutrophil degranulation Intestinal hexose absorption
Drugs
Diseases
GWAS			Bilirubin levels ( 21646302 31319653 31801373 32084209) Crohn's disease ( 22412388) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Femur bone mineral density x serum urate levels interaction ( 34046847) Hair greying ( 26926045)
Interacting Genes		15 interacting genes: ARL13B ATP6V0B CCL5 COMT EVI2B FCRL3 LMNA MGST3 MTERF3 PAGE1 RPSA SCN3B TMEM130 TMEM237 USP40	45 interacting genes: A2M ACSF2 ADH5 AHSA1 ALDOB APOM C1QA CLN8 COMMD6 DDB1 DDB2 EEF1A1 EEF1D EPB41L1 HCG11 HEBP2 HINT1 HSPA8 IL11RA ITGA6 LDHB LRP2 MT2A MTRNR2L1 NORAD OCLN OS9 PMS2P1 PSTK RACK1 RNF7 RPL30 RPS18 RPS20 RPS3A SLC12A1 SLC2A5 SRSF2 STT3A TCF25 TOMM20 TPT1 TRAPPC8 UBC VAPA
Entrez ID		6518	55230
HPRD ID		00690	07166
Ensembl ID		ENSG00000142583	ENSG00000085982
Uniprot IDs		A0A140VJK5 B4DG19 B4DT82 P22732	A0A7I2YQ75 C9JK14 Q9NVE5
PDB IDs
Enriched GO Terms of Interacting Partners?			Extracellular Exosome Translation Cytosolic Small Ribosomal Subunit Cytosolic Ribosome Ribosome Cytoplasmic Translation Translational Elongation Eukaryotic Translation Elongation Factor 1 Complex Small Ribosomal Subunit Cul4B-RING E3 Ubiquitin Ligase Complex Fructose Binding Cadherin Binding Protein Metabolic Process Host-mediated Activation Of Viral Genome Replication UV-damage Excision Repair Host-mediated Perturbation Of Viral Genome Replication Ribonucleoprotein Complex Insulin-like Growth Factor I Binding Response To Redox State Cul4A-RING E3 Ubiquitin Ligase Complex Import Across Plasma Membrane Structural Constituent Of Ribosome
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