SLC2A5 and ATP6V0B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC2A5	ATP6V0B
Description		solute carrier family 2 member 5	ATPase H+ transporting V0 subunit b
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Apical Plasma Membrane Specific Granule Membrane Sarcolemma Extracellular Exosome	Golgi Membrane Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Endosome Plasma Membrane Endosome Membrane Membrane Clathrin-coated Vesicle Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex Proton-transporting Two-sector ATPase Complex, Proton-transporting Domain Proton-transporting V-type ATPase, V0 Domain
	Molecular Function	Fructose Transmembrane Transporter Activity Protein Binding Transmembrane Transporter Activity D-glucose Transmembrane Transporter Activity Fructose Binding	Protein Binding Proton Transmembrane Transporter Activity Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Carbohydrate Metabolic Process Response To Fructose Fructose Transmembrane Transport D-glucose Import Transmembrane Transport Dehydroascorbic Acid Transport Cellular Response To Fructose Stimulus Intestinal Hexose Absorption D-glucose Transmembrane Transport Fructose Import Across Plasma Membrane	Monoatomic Ion Transport Vacuolar Acidification Lysosomal Lumen Acidification Regulation Of Macroautophagy Endosomal Lumen Acidification Intracellular PH Reduction Golgi Lumen Acidification Proton Transmembrane Transport
Pathways		Neutrophil degranulation Intestinal hexose absorption	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy
Drugs			Tiludronic acid
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		15 interacting genes: ARL13B ATP6V0B CCL5 COMT EVI2B FCRL3 LMNA MGST3 MTERF3 PAGE1 RPSA SCN3B TMEM130 TMEM237 USP40	28 interacting genes: ADGRG3 ADRB2 APOD COL4A5 EMP1 FAM210B FAS GJA8 GPR42 GPR61 INSIG2 IRAK3 KLRC1 MFF MIP MS4A3 MTNR1B NRM SLC10A1 SLC2A5 SNTA1 SPACA1 STOM TM4SF19 TMEM242 VMA21 YWHAE YWHAG
Entrez ID		6518	533
HPRD ID		00690	04759
Ensembl ID		ENSG00000142583	ENSG00000117410
Uniprot IDs		A0A140VJK5 B4DG19 B4DT82 P22732	E9PNL3 Q99437
PDB IDs			6WLW 6WM2 6WM3 6WM4 7U4T 7UNF
Enriched GO Terms of Interacting Partners?			Membrane Specific Granule Membrane Gap Junction-mediated Intercellular Transport Protein Sequestering Activity Intercellular Transport
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