USP40 and HEBP2

Number of citations of the paper that reports this interaction (PubMedID 35605301)
0

Data Source:
BioGRID (two hybrid)

		USP40	HEBP2
Description		ubiquitin specific peptidase 40	heme binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Extracellular Region Cytoplasm Mitochondrion Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	Cysteine-type Deubiquitinase Activity Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity	Protein Binding Heme Binding
	Biological Process	Proteolysis Protein Deubiquitination Regulation Of Protein Stability
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Bilirubin levels ( 21646302 31319653 31801373 32084209) Crohn's disease ( 22412388) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Femur bone mineral density x serum urate levels interaction ( 34046847) Hair greying ( 26926045)
Interacting Genes		45 interacting genes: A2M ACSF2 ADH5 AHSA1 ALDOB APOM C1QA CLN8 COMMD6 DDB1 DDB2 EEF1A1 EEF1D EPB41L1 HCG11 HEBP2 HINT1 HSPA8 IL11RA ITGA6 LDHB LRP2 MT2A MTRNR2L1 NORAD OCLN OS9 PMS2P1 PSTK RACK1 RNF7 RPL30 RPS18 RPS20 RPS3A SLC12A1 SLC2A5 SRSF2 STT3A TCF25 TOMM20 TPT1 TRAPPC8 UBC VAPA	7 interacting genes: CEBPA LAMTOR5 LRPPRC PDCD6 PLEKHF2 TMEM132D USP40
Entrez ID		55230	23593
HPRD ID		07166	09316
Ensembl ID		ENSG00000085982	ENSG00000051620
Uniprot IDs		A0A7I2YQ75 C9JK14 Q9NVE5	Q5THN1 Q9Y5Z4
PDB IDs			3R85 3R8J 3R8K 4AYZ 4B0Y 5GQQ
Enriched GO Terms of Interacting Partners?		Extracellular Exosome Translation Cytosolic Small Ribosomal Subunit Cytosolic Ribosome Ribosome Cytoplasmic Translation Translational Elongation Eukaryotic Translation Elongation Factor 1 Complex Small Ribosomal Subunit Cul4B-RING E3 Ubiquitin Ligase Complex Fructose Binding Cadherin Binding Protein Metabolic Process Host-mediated Activation Of Viral Genome Replication UV-damage Excision Repair Host-mediated Perturbation Of Viral Genome Replication Ribonucleoprotein Complex Insulin-like Growth Factor I Binding Response To Redox State Cul4A-RING E3 Ubiquitin Ligase Complex Import Across Plasma Membrane Structural Constituent Of Ribosome
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