SLC2A5 and FCRL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC2A5	FCRL3
Description		solute carrier family 2 member 5	Fc receptor like 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Apical Plasma Membrane Specific Granule Membrane Sarcolemma Extracellular Exosome	Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Microvillus Membrane Cell Projection
	Molecular Function	Fructose Transmembrane Transporter Activity Protein Binding Transmembrane Transporter Activity D-glucose Transmembrane Transporter Activity Fructose Binding	Transmembrane Signaling Receptor Activity Protein Binding Kinase Binding Phosphatase Binding
	Biological Process	Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Carbohydrate Metabolic Process Response To Fructose Fructose Transmembrane Transport D-glucose Import Transmembrane Transport Dehydroascorbic Acid Transport Cellular Response To Fructose Stimulus Intestinal Hexose Absorption D-glucose Transmembrane Transport Fructose Import Across Plasma Membrane	Negative Regulation Of Immunoglobulin Production Immune Response Cell Surface Receptor Signaling Pathway Single Fertilization Positive Regulation Of B Cell Proliferation Regulation Of Toll-like Receptor 9 Signaling Pathway Positive Regulation Of MAPK Cascade Regulation Of B Cell Differentiation Negative Regulation Of B Cell Receptor Signaling Pathway Regulation Of B Cell Activation Regulation Of Calcium Ion Import
Pathways		Neutrophil degranulation Intestinal hexose absorption
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Graves' disease ( 21841780) IgA nephropathy ( 26028593 32912934) Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes ( 21829393) Multiple sclerosis ( 21833088 31604244) Multiple sclerosis and LDL levels (pleiotropy) ( 26920376) Rheumatoid arthritis ( 24390342 30423114) Rheumatoid arthritis (ACPA-positive) ( 24532676) Selective IgA deficiency ( 27723758)
Interacting Genes		15 interacting genes: ARL13B ATP6V0B CCL5 COMT EVI2B FCRL3 LMNA MGST3 MTERF3 PAGE1 RPSA SCN3B TMEM130 TMEM237 USP40	11 interacting genes: AGPAT4 CMTM5 IGFBP5 MS4A1 PTPN11 PTPN6 SLC2A5 SLC30A3 STATH SYK ZAP70
Entrez ID		6518	115352
HPRD ID		00690	07352
Ensembl ID		ENSG00000142583	ENSG00000160856
Uniprot IDs		A0A140VJK5 B4DG19 B4DT82 P22732	Q96P31
PDB IDs
Enriched GO Terms of Interacting Partners?			Phosphotyrosine Residue Binding Neutrophil Activation Involved In Immune Response Leukocyte Activation Neutrophil Activation Beta Selection Cell Activation Antigen Receptor-mediated Signaling Pathway B Cell Receptor Signaling Pathway Regulation Of T Cell Proliferation Peptidyl-tyrosine Phosphorylation Regulation Of Cell Adhesion Mediated By Integrin B Cell Activation Lymphocyte Activation Negative Regulation Of Neutrophil Activation Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Mononuclear Cell Proliferation Regulation Of Neutrophil Activation Positive Regulation Of T Cell Activation Non-membrane Spanning Protein Tyrosine Phosphatase Activity Regulation Of Leukocyte Proliferation Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Positive Regulation Of Lymphocyte Activation Immune Response-activating Signaling Pathway T Cell Receptor Complex Myeloid Leukocyte Activation Peptidyl-tyrosine Dephosphorylation Positive Regulation Of Cell Adhesion Mediated By Integrin Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Leukocyte Cell-cell Adhesion Platelet Formation Megakaryocyte Development Positive Regulation Of Alpha-beta T Cell Proliferation Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Activation Of Immune Response Leukocyte Activation Involved In Immune Response Cell Activation Involved In Immune Response Regulation Of Lipopolysaccharide-mediated Signaling Pathway T Cell Selection Regulation Of Tumor Necrosis Factor Production Regulation Of Cytokine-mediated Signaling Pathway Negative Regulation Of Developmental Process Regulation Of B Cell Differentiation Positive Regulation Of Cell Adhesion Regulation Of Immune Response Regulation Of Cell Differentiation Regulation Of Cell-cell Adhesion
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