UPF3B and MCRS1

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UPF3B	MCRS1
Gene Name		UPF3 regulator of nonsense transcripts homolog B (yeast)	microspherule protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Exon-exon Junction Complex	Histone Acetyltransferase Complex Nucleoplasm Nucleolus Cytoplasm Actin Cytoskeleton Cell Junction Ino80 Complex MLL1 Complex
	Molecular Function	Nucleotide Binding MRNA Binding Nucleocytoplasmic Transporter Activity Protein Binding Poly(A) RNA Binding	Protein Binding Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Histone Acetyltransferase Activity (H4-K16 Specific)
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Positive Regulation Of Translation	DNA Repair DNA Recombination Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Protein Modification Process Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation
Pathways		Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing	Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: EIF6 EXOSC4 HBB MCRS1 RBBP6 RBM8A TTC19 UPF1 UPF2 XRN1	30 interactors: BLM CCDC53 CCDC85B CEP44 DAXX DVL2 FXR2 GCC1 GPBP1 IKZF1 KDM1A KIAA1958 KXD1 LIG4 LSM6 MAGEA11 MED4 NOP2 PBX2 PHC2 PINX1 PRMT5 RALYL SUV39H1 TERT TRIM37 UPF3B USHBP1 WBP11 ZBTB22
Entrez ID		65109	10445
HPRD ID		02247	11298
Ensembl ID		ENSG00000125351	ENSG00000187778
Uniprot IDs		Q9BZI7	Q7Z372 Q96EZ8
PDB IDs		1UW4 2XB2
Enriched GO Terms of Interacting Partners?		Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Histone MRNA Catabolic Process RNA Catabolic Process Histone MRNA Metabolic Process Nuclear Export Cellular Macromolecule Catabolic Process Aromatic Compound Catabolic Process MRNA Metabolic Process Catabolic Process MRNA Export From Nucleus Nuclear MRNA Surveillance Nucleocytoplasmic Transport Nuclear Transport RNA Export From Nucleus RNA Surveillance Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Transport RNA Transport RNA Localization Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Gene Expression Cytoplasmic Transport Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Metabolic Process Nitric Oxide Transport RRNA Metabolic Process Mature Ribosome Assembly Intracellular Transport Ribosome Biogenesis Cellular Metabolic Process DNA Deamination Ribosomal Subunit Export From Nucleus Mitochondrial Respiratory Chain Complex III Assembly Dosage Compensation By Inactivation Of X Chromosome Regulation Of Translational Termination RRNA Catabolic Process Nucleobase-containing Compound Metabolic Process Dosage Compensation Renal Absorption Regulation Of Translation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Heterocycle Metabolic Process Histone H4-K16 Acetylation Cellular Aromatic Compound Metabolic Process Establishment Of Localization In Cell Nucleic Acid Phosphodiester Bond Hydrolysis Maturation Of 5.8S RRNA	RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Chromosome Organization Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Biosynthetic Process Gene Expression Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Chromatin Modification Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Chromatin Organization RRNA Processing RRNA Metabolic Process Positive Regulation Of Gene Expression Ribonucleoprotein Complex Biogenesis Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Ribosome Biogenesis Telomere Maintenance Via Telomerase Telomere Maintenance Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription, DNA-templated NcRNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process DNA Replication RNA-dependent DNA Replication RNA Processing Positive Regulation Of Transcription, DNA-templated Leukocyte Differentiation RNA Splicing DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Response To X-ray T Cell Differentiation Histone Modification
Tagcloud ?			acetylates akhtar buscaino duncan gebhardt h4k16 hcf1 holz ino80 mendjan mof moz msl mueller myst myst1 nsl nucleosomal relaxed sas2 sas3 saumweber schelder stunnenberg taipale vermeulen wdr5 wilm ybf2
Tagcloud (Difference) ?			acetylates akhtar buscaino duncan gebhardt h4k16 hcf1 holz ino80 mendjan mof moz msl mueller myst myst1 nsl nucleosomal relaxed sas2 sas3 saumweber schelder stunnenberg taipale vermeulen wdr5 wilm ybf2
Tagcloud (Intersection) ?