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UPF3B
Gene Name
UPF3 regulator of nonsense transcripts homolog B (yeast)
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Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Exon-exon Junction Complex
Molecular Function
Nucleotide Binding
MRNA Binding
Nucleocytoplasmic Transporter Activity
Protein Binding
Poly(A) RNA Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
MRNA Splicing, Via Spliceosome
Transcription From RNA Polymerase II Promoter
Termination Of RNA Polymerase II Transcription
MRNA Export From Nucleus
RNA Splicing
Gene Expression
MRNA 3'-end Processing
Positive Regulation Of Translation
Pathways
Nonsense-Mediated Decay (NMD)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
mRNA Splicing
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Transcription
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
Transport of Mature Transcript to Cytoplasm
Cleavage of Growing Transcript in the Termination Region
RNA Polymerase II Transcription Termination
mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-protein Interactions
10 interactors:
EIF6
EXOSC4
HBB
MCRS1
RBBP6
RBM8A
TTC19
UPF1
UPF2
XRN1
Entrez ID
65109
HPRD ID
02247
Ensembl ID
ENSG00000125351
Uniprot IDs
Q9BZI7
PDB IDs
1UW4
2XB2
Enriched GO Terms of Interacting Partners
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Nuclear-transcribed MRNA Catabolic Process
MRNA Catabolic Process
Histone MRNA Catabolic Process
RNA Catabolic Process
Histone MRNA Metabolic Process
Nuclear Export
Cellular Macromolecule Catabolic Process
Aromatic Compound Catabolic Process
MRNA Metabolic Process
Catabolic Process
MRNA Export From Nucleus
Nuclear MRNA Surveillance
Nucleocytoplasmic Transport
Nuclear Transport
RNA Export From Nucleus
RNA Surveillance
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
MRNA Transport
RNA Transport
RNA Localization
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
Gene Expression
Cytoplasmic Transport
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
RNA Metabolic Process
Nitric Oxide Transport
RRNA Metabolic Process
Mature Ribosome Assembly
Intracellular Transport
Ribosome Biogenesis
Cellular Metabolic Process
DNA Deamination
Ribosomal Subunit Export From Nucleus
Mitochondrial Respiratory Chain Complex III Assembly
Dosage Compensation By Inactivation Of X Chromosome
Regulation Of Translational Termination
RRNA Catabolic Process
Nucleobase-containing Compound Metabolic Process
Dosage Compensation
Renal Absorption
Regulation Of Translation
Histone H4-K5 Acetylation
Histone H4-K8 Acetylation
Heterocycle Metabolic Process
Histone H4-K16 Acetylation
Cellular Aromatic Compound Metabolic Process
Establishment Of Localization In Cell
Nucleic Acid Phosphodiester Bond Hydrolysis
Maturation Of 5.8S RRNA
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