TTC23 and BHLHE40

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TTC23	BHLHE40
Gene Name		tetratricopeptide repeat domain 23	basic helix-loop-helix family, member e40
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Nucleoplasm Nucleolus Golgi Apparatus
	Molecular Function		Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription RNA Polymerase II Activating Transcription Factor Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Protein Homodimerization Activity BHLH Transcription Factor Binding MRF Binding Protein Heterodimerization Activity E-box Binding
	Biological Process		Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Circadian Rhythm Circadian Regulation Of Gene Expression Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated
Pathways			BMAL1:CLOCK,NPAS2 activates circadian gene expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: ALAS1 APP BHLHE40 CCNDBP1 CNTROB CREBZF GOLGA2 HTT KRT31 KRT40 KRTAP10-3 LDOC1 LZTS2 MAGED1 MDFI PNMA5 SPAG5 SSX2IP TADA2A TRIM10 TRIM54 ZDHHC17	49 interactors: AAMP AANAT AES APH1A ARNTL BHLHE41 BRD7 BTRC CALML3 CCNK CDPF1 CHD3 COX5B DAB1 EHHADH ENO1 FBLN1 FBXW11 GMCL1P1 HDAC1 HIVEP1 KRTAP23-1 LARP4 MAGED1 MYOD1 NAA50 NOC4L NUMBL PDE6G PLEKHB2 PRKAA1 RBFOX1 RBM23 RBPMS RHOBTB3 RHOJ SETDB1 SIN3A SMYD1 SOX15 STAT3 STK19 TOB2 TOLLIP TTC23 TXNL4B VAC14 VIM ZHX1
Entrez ID		64927	8553
HPRD ID		07777	16050
Ensembl ID		ENSG00000103852	ENSG00000134107
Uniprot IDs		Q5W5X9	O14503 Q6IB83
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule-based Process Mitotic Cell Cycle Microtubule Cytoskeleton Organization Cell Cycle Microtubule-based Transport Mitotic Cell Cycle Process Cytoskeleton-dependent Intracellular Transport Circadian Rhythm Axon Cargo Transport Neural Plate Formation Mating Neuron Apoptotic Process Regulation Of Binding Visual Learning Cell Cycle Process Visual Behavior Neuron Death Synaptic Growth At Neuromuscular Junction Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Cytoskeleton Organization Rhythmic Process Negative Regulation Of Cell Proliferation Circadian Regulation Of Gene Expression Negative Regulation Of Protein Localization To Nucleus Microtubule-based Movement Mitotic Nuclear Division Associative Learning Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Collateral Sprouting In Absence Of Injury Regulation Of Protein Phosphatase Type 2A Activity Response To Light Stimulus Negative Regulation Of Binding Regulation Of Circadian Rhythm Centrosome Organization Quinolinate Biosynthetic Process Negative Regulation Of Synaptic Transmission, Dopaminergic Cytokinesis Positive Regulation Of Intracellular Signal Transduction Microtubule Organizing Center Organization Regulation Of Tubulin Deacetylation Collateral Sprouting Axon Midline Choice Point Recognition Lactate Biosynthetic Process	Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression Rhythmic Process RNA Metabolic Process Regulation Of Circadian Rhythm Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process RNA Biosynthetic Process Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of Gene Expression Circadian Rhythm Negative Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Circadian Rhythm Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Biosynthetic Process Histone Modification Chromatin Modification Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Circadian Regulation Of Gene Expression Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Biosynthetic Process Cellular Process Macromolecule Biosynthetic Process Regulation Of Cellular Process Positive Regulation Of Skeletal Muscle Tissue Regeneration Positive Regulation Of Protein Metabolic Process Developmental Process Chromosome Organization Regulation Of Protein Metabolic Process Multicellular Organismal Development Positive Regulation Of Transcription, DNA-templated Protein Acetylation Biosynthetic Process
Tagcloud ?			ang angiogenic angiogenin cd31 colocalized fk fks glomeruli helix hypoxia lactate ldha microvascular mrnas mvd mvds nephrogenesis nks paired perinecrotic recapitulates reflected tubules univariable vegfa weaker wilms wts
Tagcloud (Difference) ?			ang angiogenic angiogenin cd31 colocalized fk fks glomeruli helix hypoxia lactate ldha microvascular mrnas mvd mvds nephrogenesis nks paired perinecrotic recapitulates reflected tubules univariable vegfa weaker wilms wts
Tagcloud (Intersection) ?