TTC23 and CREBZF

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TTC23	CREBZF
Description		tetratricopeptide repeat domain 23	CREB/ATF bZIP transcription factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cilium Cell Projection	Chromatin Nucleus Nucleoplasm Mitochondrion RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Smoothened Signaling Pathway	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Response To Virus ATF6-mediated Unfolded Protein Response Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-binding Transcription Factor Activity Integrated Stress Response Signaling
Pathways
Drugs
Diseases
GWAS		Bell's palsy ( 33602968)	Refractive error ( 32231278)
Interacting Genes		99 interacting genes: ABI1 ADCY4 AIRIM ALAS1 APP BANP BHLHE40 BLZF1 CBX8 CCDC102B CCDC24 CCNDBP1 CDK18 CDR2 CNTROB CREBZF CYSRT1 DISC1 EFCAB3 FAM161B FSD2 GOLGA2 GOLGA6L9 GPANK1 GPRASP2 GRIPAP1 HOOK2 HSF2BP HTT INSC KASH5 KDM1A KIAA1328 KLHL42 KRT15 KRT16 KRT27 KRT31 KRT34 KRT36 KRT40 KRTAP10-3 KRTAP10-8 LCN2 LDOC1 LZTS2 MAGED1 MBD3 MDFI MED12L MESD MID2 MKRN3 MTUS2 NOTO NUTM1 PICK1 PIH1D2 PLEKHG4 PNMA1 PNMA5 POLR2J3 POU6F2 PPP1R16A PRDM6 PRKAB2 PRPH PSORS1C2 RAD51D RBCK1 SPAG11B SPAG5 SPAG8 SPDEF SSX2IP TADA2A TEX13A TLE5 TRAF2 TRAPPC6A TRIB3 TRIM10 TRIM32 TRIM54 TRIM73 TRIP6 TSGA10IP UBXN11 USHBP1 XIAP XRN2 ZBED1 ZBTB16 ZBTB42 ZDHHC17 ZFHX3 ZFYVE26 ZIM2 ZRANB1	19 interacting genes: ACYP2 ATF4 ATF6B BTG3 CTNNBL1 DSCR9 HCFC1 HEY1 LCOR NFE2L1 NFE2L2 NRIP1 RALBP1 RSPH1 TIAM1 TP53 TTC23 XBP1 ZNF512B
Entrez ID		64927	58487
HPRD ID		07777	07340
Ensembl ID		ENSG00000103852	ENSG00000137504
Uniprot IDs		Q5W5X9	E9PIM0 Q9NS37
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoskeleton Keratin Filament Identical Protein Binding Intermediate Filament Organization Protein Binding Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Molecule Activity Supramolecular Fiber Organization Cytoskeleton Organization Asymmetric Cell Division Ubiquitin Protein Ligase Activity Positive Regulation Of Apoptotic Process Response To Herbicide Protein Serine/threonine Kinase Binding Transcription Coactivator Activity MRF Binding Positive Regulation Of Programmed Cell Death	ER-nucleus Signaling Pathway Cellular Response To Glucose Starvation Response To Endoplasmic Reticulum Stress Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Response To Endoplasmic Reticulum Stress DNA-binding Transcription Factor Activity Negative Regulation Of RNA Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Transcription Cis-regulatory Region Binding Nuclear Estrogen Receptor Binding Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Transcription Regulator Complex Histone Deacetylase Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleoplasm ATF6-mediated Unfolded Protein Response Response To Oxidative Stress Cellular Response To Starvation Regulation Of Intrinsic Apoptotic Signaling Pathway RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of RNA Metabolic Process PERK-mediated Unfolded Protein Response Promoter-specific Chromatin Binding Cellular Response To Oxidative Stress General Transcription Initiation Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Response To Starvation Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Nutrient Levels DNA Binding Positive Regulation Of ERAD Pathway Cellular Response To Laminar Fluid Shear Stress DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Cellular Response To Chemical Stress Negative Regulation Of Macromolecule Biosynthetic Process Intracellular Signaling Cassette Nucleus Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
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