TTC23 and EFCAB3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TTC23	EFCAB3
Description		tetratricopeptide repeat domain 23	EF-hand calcium binding domain 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cilium Cell Projection
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Smoothened Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Bell's palsy ( 33602968)	Objective response to lithium treatment ( 26503763)
Interacting Genes		99 interacting genes: ABI1 ADCY4 AIRIM ALAS1 APP BANP BHLHE40 BLZF1 CBX8 CCDC102B CCDC24 CCNDBP1 CDK18 CDR2 CNTROB CREBZF CYSRT1 DISC1 EFCAB3 FAM161B FSD2 GOLGA2 GOLGA6L9 GPANK1 GPRASP2 GRIPAP1 HOOK2 HSF2BP HTT INSC KASH5 KDM1A KIAA1328 KLHL42 KRT15 KRT16 KRT27 KRT31 KRT34 KRT36 KRT40 KRTAP10-3 KRTAP10-8 LCN2 LDOC1 LZTS2 MAGED1 MBD3 MDFI MED12L MESD MID2 MKRN3 MTUS2 NOTO NUTM1 PICK1 PIH1D2 PLEKHG4 PNMA1 PNMA5 POLR2J3 POU6F2 PPP1R16A PRDM6 PRKAB2 PRPH PSORS1C2 RAD51D RBCK1 SPAG11B SPAG5 SPAG8 SPDEF SSX2IP TADA2A TEX13A TLE5 TRAF2 TRAPPC6A TRIB3 TRIM10 TRIM32 TRIM54 TRIM73 TRIP6 TSGA10IP UBXN11 USHBP1 XIAP XRN2 ZBED1 ZBTB16 ZBTB42 ZDHHC17 ZFHX3 ZFYVE26 ZIM2 ZRANB1	9 interacting genes: CBY2 GPRASP2 HPRT1 KRT34 KRT35 OXER1 SPECC1L TTC23 WWP2
Entrez ID		64927	146779
HPRD ID		07777	08077
Ensembl ID		ENSG00000103852	ENSG00000172421
Uniprot IDs		Q5W5X9	Q8N7B9
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoskeleton Keratin Filament Identical Protein Binding Intermediate Filament Organization Protein Binding Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Molecule Activity Supramolecular Fiber Organization Cytoskeleton Organization Asymmetric Cell Division Ubiquitin Protein Ligase Activity Positive Regulation Of Apoptotic Process Response To Herbicide Protein Serine/threonine Kinase Binding Transcription Coactivator Activity MRF Binding Positive Regulation Of Programmed Cell Death	Guanine Salvage Hypoxanthine Salvage Hypoxanthine Phosphoribosyltransferase Activity Guanine Phosphoribosyltransferase Activity Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Neural Crest Cell Delamination 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding Adenine Metabolic Process Hypoxanthine Biosynthetic Process Hypoxanthine Metabolic Process Anterior Neural Tube Closure Guanine Metabolic Process GMP Salvage GMP Catabolic Process IMP Salvage Positive Regulation Of Dopamine Metabolic Process AMP Salvage Intermediate Filament Negative Regulation Of Potassium Ion Export Across Plasma Membrane Purine Ribonucleoside Salvage Structural Molecule Activity
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