BHLHE40 and MAGED1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		BHLHE40	MAGED1
Gene Name		basic helix-loop-helix family, member e40	melanoma antigen family D, 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Golgi Apparatus	Chromatin Nucleus Cytoplasm Plasma Membrane Protein Complex
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription RNA Polymerase II Activating Transcription Factor Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Protein Homodimerization Activity BHLH Transcription Factor Binding MRF Binding Protein Heterodimerization Activity E-box Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Circadian Rhythm Circadian Regulation Of Gene Expression Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated	Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of MAP Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Epithelial Cell Proliferation Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway
Pathways		BMAL1:CLOCK,NPAS2 activates circadian gene expression	Signalling by NGF Cell death signalling via NRAGE, NRIF and NADE NRAGE signals death through JNK Programmed Cell Death p75 NTR receptor-mediated signalling Role of DCC in regulating apoptosis Extrinsic Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		49 interactors: AAMP AANAT AES APH1A ARNTL BHLHE41 BRD7 BTRC CALML3 CCNK CDPF1 CHD3 COX5B DAB1 EHHADH ENO1 FBLN1 FBXW11 GMCL1P1 HDAC1 HIVEP1 KRTAP23-1 LARP4 MAGED1 MYOD1 NAA50 NOC4L NUMBL PDE6G PLEKHB2 PRKAA1 RBFOX1 RBM23 RBPMS RHOBTB3 RHOJ SETDB1 SIN3A SMYD1 SOX15 STAT3 STK19 TOB2 TOLLIP TTC23 TXNL4B VAC14 VIM ZHX1	49 interactors: AKAP9 BAG3 BHLHE40 BIRC8 BRCA2 C1orf94 CA8 CCDC33 DAB1 DLX4 DLX5 EIF3J EIF4E2 EP300 GPR135 HIVEP1 KPNA2 KRTAP19-5 MAPK3 MDFI MEOX2 MPC1 MSX2 NGFR NUMBL PITX1 PJA1 PJA2 PLK1 PRKAB2 RBFOX1 RBFOX2 RBM23 RBPMS RFX1 RHOXF2 ROR2 SIRT7 SMAP2 SNRPC TFG TRAF4 TRIM28 TTC23 TTC32 TUBA4A UNC5A XIAP ZNF488
Entrez ID		8553	9500
HPRD ID		16050	02202
Ensembl ID		ENSG00000134107	ENSG00000179222
Uniprot IDs		O14503 Q6IB83	Q9Y5V3
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression Rhythmic Process RNA Metabolic Process Regulation Of Circadian Rhythm Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process RNA Biosynthetic Process Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of Gene Expression Circadian Rhythm Negative Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Circadian Rhythm Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Biosynthetic Process Histone Modification Chromatin Modification Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Circadian Regulation Of Gene Expression Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Biosynthetic Process Cellular Process Macromolecule Biosynthetic Process Regulation Of Cellular Process Positive Regulation Of Skeletal Muscle Tissue Regeneration Positive Regulation Of Protein Metabolic Process Developmental Process Chromosome Organization Regulation Of Protein Metabolic Process Multicellular Organismal Development Positive Regulation Of Transcription, DNA-templated Protein Acetylation Biosynthetic Process	Regulation Of Metabolic Process Cellular Metabolic Process Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Binding Transcription, DNA-templated Metabolic Process Signal Transduction Negative Regulation Of Transcription From RNA Polymerase II Promoter Organ Development Cellular Response To Stimulus Positive Regulation Of Signal Transduction RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cell Death Death Regulation Of Protein Metabolic Process Multicellular Organismal Development Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Signaling Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Embryo Development Radial Glia Guided Migration Of Purkinje Cell Cellular Process Macromolecule Biosynthetic Process Apoptotic Signaling Pathway Cell Morphogenesis Involved In Differentiation Cell Communication Positive Regulation Of Metabolic Process System Development Apoptotic Process Response To Stimulus
Tagcloud ?		ang angiogenic angiogenin cd31 colocalized fk fks glomeruli helix hypoxia lactate ldha microvascular mrnas mvd mvds nephrogenesis nks paired perinecrotic recapitulates reflected tubules univariable vegfa weaker wilms wts	allelic analytical coexpression coordinator datasets esrp2 exemplifies fgfr2 gbp1 glud2 illustrates impairs indels landscape mad2l1bp mtap overlaid principle proof r353q revealing signatures slc30a8 splicing substitution tbnc tnbc tpp1 transcriptome
Tagcloud (Difference) ?		ang angiogenic angiogenin cd31 colocalized fk fks glomeruli helix hypoxia lactate ldha microvascular mrnas mvd mvds nephrogenesis nks paired perinecrotic recapitulates reflected tubules univariable vegfa weaker wilms wts	allelic analytical coexpression coordinator datasets esrp2 exemplifies fgfr2 gbp1 glud2 illustrates impairs indels landscape mad2l1bp mtap overlaid principle proof r353q revealing signatures slc30a8 splicing substitution tbnc tnbc tpp1 transcriptome
Tagcloud (Intersection) ?