RAB5C and RABAC1

Number of citations of the paper that reports this interaction (PubMedID 10329441)
0

Data Source:
HPRD (in vitro, two hybrid)

		RAB5C	RABAC1
Description		RAB5C, member RAS oncogene family	Rab acceptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Early Endosome Lipid Droplet Plasma Membrane Endomembrane System Membrane Endocytic Vesicle Early Endosome Membrane Azurophil Granule Membrane Melanosome Extracellular Exosome	Cytoplasm Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse Presynapse Glutamatergic Synapse
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Metal Ion Binding	Protein Binding Identical Protein Binding GTPase Binding Proline-rich Region Binding
	Biological Process	Intracellular Protein Transport Endocytosis Endosome Organization Protein Transport Endosomal Transport Regulation Of Endocytosis Plasma Membrane To Endosome Transport
Pathways		Golgi Associated Vesicle Biogenesis Neutrophil degranulation TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs Respiratory syncytial virus (RSV) attachment and entry
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Fibrinogen levels ( 26561523 28107422) Mean corpuscular volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Vitiligo ( 27723757) vWF and FVIII levels ( 30586737) White blood cell count ( 32888494)	Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287)
Interacting Genes		17 interacting genes: ALS2CL APP APPL2 EEA1 ERBB2 GLP1R HRAS INCA1 RABAC1 RBSN RIN2 RIN3 SGSM3 SNCA SREK1 TBC1D15 TBC1D17	98 interacting genes: ABHD4 AQP6 C6orf47 CMTM3 COQ8A CRB3 CREB3 CYB5R3 CYBRD1 DUSP12 EI24 EMP1 F11R FHIP1B FXR1 FXR2 GDI1 GPR152 HRAS HRG HSD17B13 LEMD3 LMNA LNX1 LTBR MAD2L1 MCF2L MIEF2 NAT14 NDRG2 NDRG4 NIF3L1 NR3C2 NTAQ1 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP2 REEP5 RETREG3 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RNF5 RPS20 RRAS2 S100B SGK1 SH3GL3 SH3GLB1 SLAMF6 SLC10A1 SLC18A1 SNCA SNX1 SNX10 SNX11 SNX15 SNX17 SNX8 SPG21 SSR3 STIM1 STOML2 SYT16 TMEM115 TMEM14B TMEM42 TMX2 TNIP1 TRIM32 TSHR TUBB2A TXN2 UBE2I VAMP2 VIM VTA1 WIPI2 ZFYVE21
Entrez ID		5878	10567
HPRD ID		04947	05375
Ensembl ID		ENSG00000108774	ENSG00000105404
Uniprot IDs		P51148	Q9UI14
PDB IDs		4KYI
Enriched GO Terms of Interacting Partners?		Cytoplasmic Vesicle Vesicle-mediated Transport GTPase Activator Activity Regulation Of Long-term Neuronal Synaptic Plasticity Import Into Cell Endocytosis Endosomal Transport Small GTPase Binding Endosome Regulation Of Endocytosis Regulation Of Neuronal Synaptic Plasticity Early Endosome Intracellular Transport Intracellular Signaling Cassette Cellular Localization Glial Cell Development Establishment Of Localization In Cell Early Endosome Membrane Guanyl-nucleotide Exchange Factor Activity Presynapse Protein Tetramerization Regulation Of Cell Projection Assembly Schwann Cell Development Regulation Of Cilium Assembly Regulation Of Neurotransmitter Uptake Small GTPase-mediated Signal Transduction Cellular Response To Copper Ion Cellular Response To Growth Factor Stimulus Regulation Of Presynapse Organization Regulation Of Presynapse Assembly Positive Regulation Of Protein Targeting To Membrane Amyloid Fibril Formation Regulation Of Vesicle-mediated Transport Regulation Of Cellular Component Organization Microglial Cell Activation Regulation Of Catalytic Activity Response To Growth Factor Recycling Endosome Regulation Of Protein Targeting To Membrane Leukocyte Activation Involved In Inflammatory Response Response To Copper Ion Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endocytosis Signal Transduction Glucagon-like Peptide 1 Receptor Activity Response To Desipramine	GTPase Activity GTP Binding GDP Binding Membrane Endosome G Protein Activity Establishment Of Localization In Cell Vesicle-mediated Transport Protein Transport Intracellular Protein Localization Establishment Of Protein Localization Cellular Localization Intracellular Protein Transport Protein Binding Endosomal Transport Regulation Of Neuronal Synaptic Plasticity Lipid Binding Secretory Granule Membrane Intracellular Transport Phosphatidylinositol Binding Endocytosis Vesicle Organization Regulation Of Long-term Neuronal Synaptic Plasticity Early Endosome Regulation Of Cellular Component Organization Endosome Organization Regulation Of Vesicle-mediated Transport Vesicle-mediated Transport In Synapse Synaptic Vesicle Exocytosis Localization Within Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane Rab Protein Signal Transduction Import Into Cell Early Endosome To Golgi Transport Early Endosome Membrane Endomembrane System Cytoplasmic Vesicle Endoplasmic Reticulum Membrane Organelle Organization Synaptic Vesicle Membrane Identical Protein Binding Autophagosome Assembly Plasma Membrane To Endosome Transport Small GTPase-mediated Signal Transduction Regulation Of Synaptic Plasticity Establishment Of Organelle Localization Autophagosome Organization Endosome Membrane Endocytic Vesicle Organelle Localization
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