RAB5C and TBC1D17

Number of citations of the paper that reports this interaction (PMID 16923123)
31

Data Source:
BioGRID (two hybrid)

		RAB5C	TBC1D17
Gene Name		RAB5C, member RAS oncogene family	TBC1 domain family, member 17
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Early Endosome Lipid Particle Plasma Membrane Endocytic Vesicle Early Endosome Membrane Melanosome Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Autophagic Vacuole Cytosol Cytoplasmic Vesicle
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Rab GTPase Activator Activity Protein Binding
	Biological Process	Intracellular Protein Transport Regulation Of Endocytosis Rab Protein Signal Transduction Plasma Membrane To Endosome Transport	Autophagy Protein Transport Positive Regulation Of Rab GTPase Activity Retrograde Transport, Endosome To Golgi Regulation Of Cilium Assembly
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: APP APPL2 EEA1 RABAC1 RBSN RIN2 RIN3 SGSM3 TBC1D15 TBC1D17	19 interactors: ASCC2 CALCOCO1 CCT5 CDKN2D DHX29 FBL GABARAPL1 GPS1 GTF3C1 MAP1LC3A MAP1LC3B NIPSNAP1 OPTN RAB1A RAB5A RAB5B RAB5C SLC1A5 TAX1BP1
Entrez ID		5878	79735
HPRD ID		04947	15471
Ensembl ID		ENSG00000108774	ENSG00000104946
Uniprot IDs		P51148	Q9HA65
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Positive Regulation Of Ras GTPase Activity Positive Regulation Of Hydrolase Activity Regulation Of Ras GTPase Activity Regulation Of Catalytic Activity Regulation Of Ras Protein Signal Transduction Vesicle-mediated Transport Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Catalytic Activity Regulation Of GTPase Activity Regulation Of Signal Transduction Regulation Of Signaling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Endosomal Transport Endocytosis Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Regulation Of Intracellular Signal Transduction Mating Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Metabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Regulation Of ERBB Signaling Pathway Synaptic Vesicle To Endosome Fusion Feeding Behavior Cholesterol Metabolic Process Synaptic Growth At Neuromuscular Junction Regulation Of Receptor Activity Sterol Metabolic Process Neuromuscular Process Intracellular Transport Collateral Sprouting In Absence Of Injury Regulation Of Protein Binding Transition Metal Ion Homeostasis Transport Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Peptidyl-tyrosine Phosphorylation Axon Choice Point Recognition Plasma Membrane To Endosome Transport Locomotory Behavior Establishment Of Localization In Cell	Macroautophagy Autophagic Vacuole Assembly Cellular Response To Starvation Rab Protein Signal Transduction Autophagy Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Nucleophagy Response To Nutrient Levels Response To Extracellular Stimulus Vacuole Organization Mitochondrion Degradation Organelle Disassembly Plasma Membrane To Endosome Transport Ras Protein Signal Transduction Response To External Stimulus Cellular Response To Nitrogen Starvation Cellular Response To Stress Membrane Fusion Cytoplasmic Transport Regulation Of Endocytosis Membrane Organization Organelle Assembly Response To Stimulus Endosomal Transport Intracellular Protein Transport Response To Stress Histone Glutamine Methylation Extracellular Amino Acid Transport Small GTPase Mediated Signal Transduction Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Peptidyl-glutamine Methylation Golgi Organization Response To Other Organism Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Endosome Size Response To Biotic Stimulus Regulation Of Vesicle-mediated Transport Interleukin-8 Production SnoRNA Metabolic Process Negative Regulation Of Receptor Recycling Cellular Protein Localization Mitochondrion Organization Protein Transport Negative Regulation Of Intracellular Signal Transduction Vesicle-mediated Transport Endomembrane System Organization 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter
Tagcloud ?		cdc42 compartment coordinately cytomegalovirus ectopic encode golgi hcmv herpesviruses infectious micrornas mirna mirnas mirs morphogenesis noninfectious rab11a reorganization resemble secretory sirnas snap23 stacks ul112 uncovered us5 vac vamp3 virion
Tagcloud (Difference) ?		cdc42 compartment coordinately cytomegalovirus ectopic encode golgi hcmv herpesviruses infectious micrornas mirna mirnas mirs morphogenesis noninfectious rab11a reorganization resemble secretory sirnas snap23 stacks ul112 uncovered us5 vac vamp3 virion
Tagcloud (Intersection) ?