SMYD3 and H3F3C

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		SMYD3	H3F3C
Gene Name		SET and MYND domain containing 3	H3 histone, family 3C
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleosome Nuclear Euchromatin
	Molecular Function	RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Binding RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding	Nucleosomal DNA Binding Protein Heterodimerization Activity
	Biological Process	Chromatin Organization Nucleosome Assembly Negative Regulation Of Protein Kinase Activity Myotube Cell Development Positive Regulation Of Peptidyl-serine Phosphorylation Histone Lysine Methylation Establishment Of Protein Localization Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Dexamethasone Stimulus	Positive Regulation Of Cell Growth
Pathways		Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		16 interactors: APP CAMK2B CYP39A1 EED EZH2 H3F3C HELZ HIST3H3 HSP90AA1 NDUFAB1 NFYB PBX2 POLR2K TRIT1 VANGL1 ZNF557	12 interactors: KAT6A KDM1A KDM4B NASP PRMT5 PRMT6 PRMT7 SETMAR SMYD1 SMYD3 SUV39H1 WHSC1L1
Entrez ID		64754	440093
HPRD ID		12297	18443
Ensembl ID		ENSG00000185420	ENSG00000188375
Uniprot IDs		B3KN46 Q9H7B4	Q6NXT2
PDB IDs		3MEK 3OXF 3OXG 3OXL 3PDN 3QWP 3RU0	3KV4
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression, Epigenetic Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Heat Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression, Epigenetic Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Inhibitory G-protein Coupled Receptor Phosphorylation Positive Regulation Of Cellular Metabolic Process Cellular Response To Heat Neuromuscular Process Controlling Balance Synaptic Growth At Neuromuscular Junction Activation Of Meiosis Involved In Egg Activation Innate Immune Response Regulation Of Synapse Structure Or Activity Cellular Metabolic Process Bile Acid Catabolic Process Collateral Sprouting In Absence Of Injury Response To Heat Transcription, DNA-templated Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Protein Import Into Mitochondrial Outer Membrane Activation Of Meiosis Cholesterol Metabolic Process Histone Methylation Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Collateral Sprouting Axon Midline Choice Point Recognition Protein Lipoylation Sterol Metabolic Process Neuromuscular Process Regulation Of Cell Cycle Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Metabolic Process Gene Expression Regulation Of Synaptic Transmission, Cholinergic Axon Choice Point Recognition	Chromatin Modification Chromatin Organization Chromosome Organization Histone Modification Histone Methylation Protein Methylation Methylation Organelle Organization Peptidyl-amino Acid Modification Histone Lysine Methylation Peptidyl-lysine Methylation Peptidyl-lysine Modification Histone H4-R3 Methylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Peptidyl-arginine N-methylation Histone Arginine Methylation Peptidyl-arginine Methylation Cellular Protein Modification Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Gene Expression Regulation Of Gene Expression Cellular Macromolecular Complex Assembly Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Peptidyl-lysine Dimethylation Protein Metabolic Process Nucleosome Assembly Regulation Of Metabolic Process Chromatin Assembly
Tagcloud ?		blocked bovine conversely early embryonic embryos epigenetic fertilization germinal involves lysine mammalian maturation methyltransferase microinjection modifications mynd nanog oocyte oocytes plays program pronuclear regulates reprogramming sirna stage throughout vesicle
Tagcloud (Difference) ?		blocked bovine conversely early embryonic embryos epigenetic fertilization germinal involves lysine mammalian maturation methyltransferase microinjection modifications mynd nanog oocyte oocytes plays program pronuclear regulates reprogramming sirna stage throughout vesicle
Tagcloud (Intersection) ?