B3GAT1 and SH3GL1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		B3GAT1	SH3GL1
Description		beta-1,3-glucuronyltransferase 1	SH3 domain containing GRB2 like 1, endophilin A2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane	Podosome Cytoplasm Endosome Cytosol Membrane Early Endosome Membrane Cell Projection Anchoring Junction Presynapse Glutamatergic Synapse
	Molecular Function	Protein Binding Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Activity Transferase Activity Metal Ion Binding	Protein Binding Lipid Binding Identical Protein Binding Cadherin Binding
	Biological Process	Carbohydrate Metabolic Process Glycosaminoglycan Biosynthetic Process Protein Glycosylation Visual Learning Chondroitin Sulfate Proteoglycan Biosynthetic Process	Endocytosis Signal Transduction Central Nervous System Development
Pathways		Glycosaminoglycan-protein linkage region biosynthesis	EGFR downregulation Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell
Drugs		D-tartaric acid Uridine-5'-Diphosphate
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514) N-glycan levels ( 21908519) Neonatal white matter microstructure ( 33009551) Prostate cancer ( 29892016) Schizophrenia ( 33169155) Serum alkaline phosphatase levels ( 33547301) Verbal declarative memory ( 25648963)	Appendicular lean mass ( 33097823) Hematocrit ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		3 interacting genes: CMTM7 HLA-DMA SH3GL1	35 interacting genes: ARHGAP1 ARHGAP8 AXIN1 B3GAT1 CCDC50 CMTM5 CREBBP DNM1 DNM1L DPPA4 DPYSL4 EEIG1 FBXO32 GPKOW ITCH ITSN2 MAL2 MTA1 NUTM2F PDCD6IP PML PRB3 PSMB1 PTPRO RHEX SCAMP5 SEPTIN8 SH2D4A SH3D19 SH3GL3 SOCS1 SPG21 SYNJ1 VPS37C YWHAZ
Entrez ID		27087	6455
HPRD ID		06969	03462
Ensembl ID		ENSG00000109956	ENSG00000141985
Uniprot IDs		Q9P2W7	Q6FGM0 Q99961
PDB IDs		1V82 1V83 1V84
Enriched GO Terms of Interacting Partners?		B-1a B Cell Differentiation B-1 B Cell Differentiation	Negative Regulation Of Endocytic Recycling Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cytoplasm Membrane Fission
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