SH3BGR and FCHSD2

Number of citations of the paper that reports this interaction (PMID 18654987)
7

Data Source:
BioGRID (two hybrid)

		SH3BGR	FCHSD2
Gene Name		SH3 domain binding glutamate-rich protein	FCH and double SH3 domains 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol
	Molecular Function	SH3/SH2 Adaptor Activity SH3 Domain Binding	Protein Binding
	Biological Process	Protein Complex Assembly Positive Regulation Of Signal Transduction
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 23266558)
Protein-Protein Interactions		2 interactors: CAPN1 FCHSD2	25 interactors: ABCF3 C2orf73 C9orf78 CASK CCDC158 CCDC85B CCT2 CFAP36 CHKA DAPP1 FAM9B HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 MSL1 MTUS2 PDE4DIP SH3BGR SRP72 VCPIP1 WAS WASL
Entrez ID		6450	9873
HPRD ID		03753	13321
Ensembl ID		ENSG00000185437	ENSG00000137478
Uniprot IDs		P55822	E9PG19 O94868
PDB IDs			2DL5 2DL7
Enriched GO Terms of Interacting Partners?		Receptor Catabolic Process Receptor Metabolic Process Extracellular Matrix Disassembly	Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Arp2/3 Complex-mediated Actin Nucleation Endocytosis Regulation Of Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Toxin Transport Cellular Response To Interleukin-4 Vesicle-mediated Transport Response To Interleukin-4 Regulation Of Protein Folding In Endoplasmic Reticulum Protein Complex Assembly Phagocytosis Actin Filament-based Movement Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Golgi Organization Endoplasmic Reticulum Membrane Fusion Negative Regulation Of Membrane Tubulation Cerebellum Structural Organization Transport Actin Polymerization Or Depolymerization Cellular Protein Complex Assembly Zonula Adherens Maintenance Vesicle Transport Along Actin Filament Cellular Component Assembly Ephrin Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Golgi Reassembly Dentinogenesis Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Axon Guidance Protein Localization To Endoplasmic Reticulum Positive Regulation Of Clathrin-mediated Endocytosis Movement Of Cell Or Subcellular Component Response To Unfolded Protein Immune Response-regulating Signaling Pathway Choline Metabolic Process Golgi Inheritance Protein K11-linked Deubiquitination
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