SH3BGR and TFF3

Data Source: HiPPIP (Novel)

		SH3BGR	TFF3
Name		SH3 domain binding glutamate rich protein	trefoil factor 3
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Region Extracellular Space Cytoplasm Secretory Granule
	Molecular Function	Protein Binding SH3 Domain Binding	Protein Binding Identical Protein Binding
	Biological Process	None	Regulation Of Glucose Metabolic Process Maintenance Of Gastrointestinal Epithelium
Pathways		None	Estrogen-dependent gene expression
GWAS		No GWAS studies recorded	Spatial memory ( 31596458 )
Novel Interactors		5 novel interactors: PCNT PWP2 SLC19A1 SMAD7 TFF3	2 novel interactors: SH3BGR TRAPPC10
Interacting Genes		2 interacting genes: CAPN1 FCHSD2	4 interacting genes: PCBD1 SGTA UBQLN2 ZSCAN9
Entrez ID		6450	7033
HPRD ID		03753	02797
Ensembl ID		ENSG00000185437	ENSG00000160180
Uniprot IDs		A0A804CBI3 C9JJT2 P55822	Q07654
PDB IDs		Not available	1E9T 1PE3 6V1C
GO Terms Enriched among Interactors		Beta-catenin Destruction Complex Disassembly Positive Regulation Of Chondrocyte Hypertrophy Methotrexate Transport Methotrexate Transmembrane Transporter Activity Folate:monoatomic Anion Antiporter Activity Stereocilium Shaft Positive Regulation Of Chondrocyte Development Folate Import Across Plasma Membrane 2',3'-cyclic GMP-AMP Binding Cyclic-GMP-AMP Transmembrane Transporter Activity	Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Tyrosine Biosynthetic Process Phenylalanine 4-monooxygenase Activity Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine TRC Complex Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Proteolysis Involved In Protein Catabolic Process BAT3 Complex Binding Negative Regulation Of Clathrin-dependent Endocytosis Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Tetrahydrobiopterin Biosynthetic Process Negative Regulation Of ERAD Pathway Response To Endoplasmic Reticulum Stress Tetrahydrobiopterin Metabolic Process Post-translational Protein Targeting To Endoplasmic Reticulum Membrane TRAPPII Protein Complex Pteridine-containing Compound Biosynthetic Process Tyrosine Metabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane TRAPP Complex Negative Regulation Of Receptor Internalization Early Endosome To Golgi Transport Regulation Of Clathrin-dependent Endocytosis Regulation Of Protein Catabolic Process Regulation Of Proteolysis