SH3BGR and SLC19A1

Data Source: HiPPIP (Novel)

		SH3BGR	SLC19A1
Name		SH3 domain binding glutamate rich protein	solute carrier family 19 member 1
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Brush Border Membrane
	Molecular Function	Protein Binding SH3 Domain Binding	Protein Binding Folic Acid Binding Organic Anion Transmembrane Transporter Activity Folic Acid Transmembrane Transporter Activity Folate:monoatomic Anion Antiporter Activity Antiporter Activity Methotrexate Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity 2',3'-cyclic GMP-AMP Binding Vitamin Transmembrane Transporter Activity Cyclic-GMP-AMP Transmembrane Transporter Activity
	Biological Process	None	Xenobiotic Transmembrane Transport Female Pregnancy Response To Xenobiotic Stimulus Response To Toxic Substance Organic Anion Transport Folic Acid Transport Folic Acid Metabolic Process Vitamin Transport Methotrexate Transport Monoatomic Anion Transmembrane Transport Folate Transmembrane Transport Cyclic-GMP-AMP Transmembrane Import Across Plasma Membrane Positive Regulation Of CGAS/STING Signaling Pathway Transport Across Blood-brain Barrier Folate Import Across Plasma Membrane
Pathways		None	Metabolism of folate and pterines
GWAS		No GWAS studies recorded	Ankle injury ( 28957384 )
Novel Interactors		5 novel interactors: PCNT PWP2 SLC19A1 SMAD7 TFF3	2 novel interactors: SH3BGR TRAPPC10
Interacting Genes		2 interacting genes: CAPN1 FCHSD2	1 interacting genes: KRT26
Entrez ID		6450	6573
HPRD ID		03753	02691
Ensembl ID		ENSG00000185437	ENSG00000173638
Uniprot IDs		A0A804CBI3 C9JJT2 P55822	P41440
PDB IDs		Not available	7TX6 7TX7 7XPZ 7XQ0 7XQ1 7XQ2 7XTK 8DEP 8GOE 8GOF 8HII 8HIJ 8HIK 9JOZ 9JRI 9JRK 9JRL 9JRM 9JRN
GO Terms Enriched among Interactors		Beta-catenin Destruction Complex Disassembly Positive Regulation Of Chondrocyte Hypertrophy Methotrexate Transport Methotrexate Transmembrane Transporter Activity Folate:monoatomic Anion Antiporter Activity Stereocilium Shaft Positive Regulation Of Chondrocyte Development Folate Import Across Plasma Membrane 2',3'-cyclic GMP-AMP Binding Cyclic-GMP-AMP Transmembrane Transporter Activity	TRAPPII Protein Complex TRAPP Complex Early Endosome To Golgi Transport