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SELP and SELPLG
Number of citations of the paper that reports this interaction (PubMedID
9128259
)
54
Data Source:
HPRD
(in vitro, in vivo)
SELP
SELPLG
Description
selectin P
selectin P ligand
Image
GO Annotations
Cellular Component
Extracellular Space
Plasma Membrane
External Side Of Plasma Membrane
Membrane
Platelet Dense Granule Membrane
Platelet Alpha Granule Membrane
Uropod
Plasma Membrane
Membrane
Plasma Membrane Raft
Molecular Function
Lipopolysaccharide Binding
Integrin Binding
Calcium Ion Binding
Protein Binding
Heparin Binding
Carbohydrate Binding
Sialic Acid Binding
Fucose Binding
Glycosphingolipid Binding
Metal Ion Binding
Calcium-dependent Protein Binding
Oligosaccharide Binding
Virus Receptor Activity
Signaling Receptor Binding
Protein Binding
Biological Process
Positive Regulation Of Leukocyte Migration
Inflammatory Response
Cell Adhesion
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Leukocyte Cell-cell Adhesion
Positive Regulation Of Platelet Activation
Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Response To Lipopolysaccharide
Regulation Of Integrin Activation
Response To Cytokine
Defense Response To Gram-negative Bacterium
Leukocyte Migration
Leukocyte Tethering Or Rolling
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Cell-cell Adhesion
Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Positive Regulation Of Leukocyte Tethering Or Rolling
Cell Adhesion
Symbiont Entry Into Host Cell
Leukocyte Migration
Leukocyte Tethering Or Rolling
Leukocyte Adhesive Activation
Cellular Response To Interleukin-6
Pathways
Platelet degranulation
Cell surface interactions at the vascular wall
Cell surface interactions at the vascular wall
Drugs
Heparin
N-acetyl-alpha-neuraminic acid
Dalteparin
Nadroparin
Crizanlizumab
Neihulizumab
Diseases
GWAS
Activated partial thromboplastin time (
22703881
)
Blood protein levels (
30072576
)
Hippocampal atrophy (
22745009
)
Inflammatory bowel disease (
26192919
)
L-selectin levels (
25576479
)
Late-onset Alzheimer's disease (
27770636
)
Monocyte count (
32888494
)
Optic disc size (
31809533
)
Soluble levels of adhesion molecules (
20167578
)
Total ventricular volume (
21116278
)
Acne (severe) (
24927181
)
Blood protein levels (
30072576
)
Brain morphology (MOSTest) (
32665545
)
Conduct disorder (symptom count) (
20585324
)
Interacting Genes
10 interacting genes:
AP1M1
CD24
EZR
FUT4
GP1BA
SELPLG
SERPING1
SNX17
SNX27
VCAN
14 interacting genes:
BACE1
CTSG
GALNT4
MAGEA1
MSN
SELE
SELL
SELP
SLC13A1
SYK
TNIP1
TPST1
TPST2
VCAN
Entrez ID
6403
6404
HPRD ID
01433
02845
Ensembl ID
ENSG00000174175
ENSG00000110876
Uniprot IDs
B2R785
P16109
Q5R341
Q6NUL9
Q14242
PDB IDs
1FSB
1G1Q
1G1R
1G1S
1HES
1G1S
Enriched GO Terms of Interacting Partners
?
Localization Within Membrane
Uropod
Fibrinolysis
Cell Migration
Cell Adhesion
Cellular Localization
Receptor-mediated Endocytosis
Establishment Of Localization In Cell
Negative Regulation Of Blood Coagulation
Negative Regulation Of Hemostasis
Negative Regulation Of Coagulation
Cell Motility
Intracellular Protein Localization
IgE Receptor Activity
Vesicle-mediated Transport
Leukocyte Migration
Cell Activation
Cell Surface
Regulation Of Platelet Activation
Leukocyte Cell-cell Adhesion
Plasma Membrane Raft
Immunological Synapse
Intracellular Protein Transport
Establishment Of Natural Killer Cell Polarity
Negative Regulation Of Transforming Growth Factor Beta3 Production
B Cell Receptor Transport Into Membrane Raft
Chemokine Receptor Transport Out Of Membrane Raft
Membrane
Negative Regulation Of Wound Healing
Regulation Of Blood Coagulation
Receptor Internalization
Protein Localization To Membrane
Regulation Of Hemostasis
Negative Regulation Of Complement Activation, Lectin Pathway
Positive Regulation Of Type I Hypersensitivity
External Side Of Plasma Membrane
Fc-epsilon Receptor I Complex
Lewis X Epitope Biosynthetic Process
Leukocyte Adhesive Activation
Terminal Web Assembly
Early Endosome
Endocytic Recycling
Glomerular Parietal Epithelial Cell Differentiation
Blood Coagulation
Regulation Of Immune System Process
Interphotoreceptor Matrix
Negative Regulation Of Mast Cell Apoptotic Process
Serotonin Secretion By Platelet
Fc-gamma Receptor III Complex
Positive Regulation Of Type III Hypersensitivity
Leukocyte Cell-cell Adhesion
Leukocyte Migration
Oligosaccharide Binding
Carbohydrate Binding
Leukocyte Tethering Or Rolling
Sialic Acid Binding
Protein-tyrosine Sulfotransferase Activity
Leukocyte Adhesion To Vascular Endothelial Cell
Cell-cell Adhesion
Cell Adhesion
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Cell Migration
Glycosphingolipid Binding
Regulation Of Platelet Activation
Cell Motility
Positive Regulation Of Leukocyte Tethering Or Rolling
Regulation Of Leukocyte Tethering Or Rolling
3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Golgi Lumen
Response To Lipopolysaccharide
Immune System Process
Phospholipase Binding
Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Response To Molecule Of Bacterial Origin
Positive Regulation Of Cell-cell Adhesion
Positive Regulation Of Immune System Process
Neutrophil Activation
Positive Regulation Of Receptor Internalization
Regulation Of Platelet Aggregation
Regulation Of Leukocyte Cell-cell Adhesion
Heparin Binding
Regulation Of Immune System Process
Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Regulation Of Cellular Extravasation
Pattern Recognition Receptor Signaling Pathway
Regulation Of Inflammatory Response
Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Innate Immune Response-activating Signaling Pathway
Trans-Golgi Network
Signaling Receptor Ligand Precursor Processing
Response To Lipid
Biofilm Matrix Disassembly
Regulation Of Defense Response
Mevalonate Kinase Activity
Interleukin-15 Receptor Binding
Positive Regulation Of Interleukin-3 Production
Peptidyl-tyrosine Sulfation
Golgi-associated Vesicle Lumen
Activation Of Innate Immune Response
Response To External Biotic Stimulus
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Tagcloud (Difference)
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Tagcloud (Intersection)
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