SELP and CD24

Number of citations of the paper that reports this interaction (PMID 9129046)
41

Data Source:
BioGRID (pull down)

		SELP	CD24
Gene Name		selectin P (granule membrane protein 140kDa, antigen CD62)	CD24 molecule
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleoplasm Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Platelet Dense Granule Membrane Platelet Alpha Granule Membrane	Plasma Membrane Cell Surface Membrane Anchored Component Of Membrane Membrane Raft
	Molecular Function	Lipopolysaccharide Binding Glycoprotein Binding Protein Binding Heparin Binding Sialic Acid Binding Fucose Binding Glycosphingolipid Binding Calcium-dependent Protein Binding Oligosaccharide Binding	Signal Transducer Activity Protein Binding Protein Kinase Binding Protein Tyrosine Kinase Activator Activity
	Biological Process	Platelet Degranulation Positive Regulation Of Leukocyte Migration Inflammatory Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Blood Coagulation Positive Regulation Of Platelet Activation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Platelet Activation Response To Lipopolysaccharide Regulation Of Integrin Activation Defense Response To Gram-negative Bacterium Leukocyte Migration Leukocyte Tethering Or Rolling	Response To Hypoxia Cell Activation Regulation Of Cytokine-mediated Signaling Pathway Response To Molecule Of Bacterial Origin Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Axon Guidance Wnt Signaling Pathway Single Organismal Cell-cell Adhesion Cell Migration Regulation Of Epithelial Cell Differentiation T Cell Costimulation B Cell Receptor Transport Into Membrane Raft Chemokine Receptor Transport Out Of Membrane Raft Negative Regulation Of Transforming Growth Factor Beta3 Production Positive Regulation Of Activated T Cell Proliferation Regulation Of Phosphorylation Cholesterol Homeostasis Positive Regulation Of MAP Kinase Activity Regulation Of MAPK Cascade Response To Estrogen Respiratory Burst Positive Regulation Of Protein Tyrosine Kinase Activity Glomerular Visceral Epithelial Cell Differentiation Glomerular Parietal Epithelial Cell Differentiation Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Nephron Tubule Epithelial Cell Differentiation
Pathways		Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation Cell surface interactions at the vascular wall	Axon guidance L1CAM interactions
Drugs		Heparin O-Sialic Acid Dalteparin Nadroparin
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Hippocampal atrophy ( 22745009) Soluble levels of adhesion molecules ( 20167578) Total ventricular volume ( 21116278)
Protein-Protein Interactions		10 interactors: AP1M1 CD24 EZR FUT4 GP1BA SELPLG SERPING1 SNX17 SNX27 VCAN	1 interactors: SELP
Entrez ID		6403	100133941
HPRD ID		01433
Ensembl ID		ENSG00000174175
Uniprot IDs		P16109 Q5R341 Q6NUL9	B6EC88 P25063
PDB IDs		1FSB 1G1Q 1G1R 1G1S 1HES 1KJD
Enriched GO Terms of Interacting Partners?		Cell Activation Vesicle-mediated Transport Blood Coagulation, Intrinsic Pathway Cell Adhesion Fibrinolysis Endosomal Transport Cellular Protein Localization Cellular Localization Negative Regulation Of Blood Coagulation Leukocyte Cell-cell Adhesion Negative Regulation Of Coagulation Negative Regulation Of Wound Healing Intracellular Protein Transport Chemokine Receptor Transport Out Of Membrane Raft B Cell Receptor Transport Into Membrane Raft Negative Regulation Of Transforming Growth Factor Beta3 Production Establishment Of Natural Killer Cell Polarity Protein Localization Blood Coagulation Hemostasis Regulation Of Blood Coagulation Establishment Of Localization In Cell Negative Regulation Of Complement Activation, Lectin Pathway Leukocyte Adhesive Activation Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Leukocyte Activation Immune System Process Single Organismal Cell-cell Adhesion Locomotion Regulation Of T Cell Homeostatic Proliferation Glomerular Parietal Epithelial Cell Differentiation Positive Regulation Of Nephron Tubule Epithelial Cell Differentiation Regulation Of Wound Healing Regulation Of Body Fluid Levels Wound Healing Protein Transport Membrane To Membrane Docking Positive Regulation Of Cell-cell Adhesion Mediated By Integrin Positive Regulation Of Integrin Activation Positive Regulation Of B Cell Apoptotic Process Endocytosis Protein Activation Cascade Establishment Of Protein Localization Movement Of Cell Or Subcellular Component Negative Regulation Of Transforming Growth Factor Beta Production Intracellular Transport Response To Wounding Platelet Activation Pigment Granule Maturation L-fucose Catabolic Process	Selenium Compound Metabolic Process Positive Regulation Of Platelet Activation Regulation Of Integrin Activation Leukocyte Tethering Or Rolling Cellular Extravasation Regulation Of Platelet Activation Positive Regulation Of Blood Coagulation Defense Response To Gram-negative Bacterium Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Coagulation Positive Regulation Of Wound Healing Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Platelet Degranulation Positive Regulation Of Leukocyte Migration Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Blood Coagulation Regulation Of Leukocyte Migration Regulation Of Wound Healing Post-embryonic Development Defense Response To Bacterium Platelet Activation Leukocyte Migration Locomotory Behavior Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Positive Regulation Of Cell Activation Response To Lipopolysaccharide Leukocyte Cell-cell Adhesion Positive Regulation Of Cell Migration Regulation Of Protein Complex Assembly Response To Molecule Of Bacterial Origin Positive Regulation Of Cell Motility Exocytosis Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Blood Coagulation Response To Oxidative Stress Inflammatory Response Hemostasis Regulation Of Cell Activation Response To Bacterium Growth
Tagcloud ?			15q21 6q21 atgs chromosome converted distantly dnas frame glycosyl gpi granulocytes gtgs homologous homologues hybrids leaving mapped monochromosomal multigene originating p36 q22 reading retained somatic southern tentatively unlikely yq11
Tagcloud (Difference) ?			15q21 6q21 atgs chromosome converted distantly dnas frame glycosyl gpi granulocytes gtgs homologous homologues hybrids leaving mapped monochromosomal multigene originating p36 q22 reading retained somatic southern tentatively unlikely yq11
Tagcloud (Intersection) ?