DMRTC2 and IRF9

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		DMRTC2	IRF9
Gene Name		DMRT-like family C2	interferon regulatory factor 9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	XY Body Nucleus	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Homodimerization Activity Metal Ion Binding	Regulatory Region DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Male Meiosis I Spermatid Nucleus Elongation Sex Differentiation Positive Regulation Of Histone H3-K9 Dimethylation Positive Regulation Of Histone H3-K9 Trimethylation	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Type I Interferon Biosynthetic Process Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway
Pathways			Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: IRF9 TXNRD1	19 interactors: ARID3B DACH2 DMRTC2 HOXC9 IFNA1 IRF1 IRF2BP1 MYO1F NFKB1 NR2E3 POU2F1 RELA S100A13 STAT1 STAT2 TLX2 TLX3 TOP1 VENTX
Entrez ID		63946	10379
HPRD ID		16829	00960
Ensembl ID		ENSG00000142025	ENSG00000213928
Uniprot IDs		Q8IXT2	Q00978
PDB IDs
Enriched GO Terms of Interacting Partners?		Detoxification Of Mercury Ion Type I Interferon Biosynthetic Process Type I Interferon Production Nucleobase-containing Small Molecule Interconversion Response To Mercury Ion Cytokine Biosynthetic Process Cytokine Metabolic Process	Regulation Of Innate Immune Response Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Interleukin-12 Biosynthetic Process RNA Metabolic Process Defense Response To Virus Gene Expression Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Other Organism Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Response To Biotic Stimulus Cellular Nitrogen Compound Metabolic Process Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Response To Virus Response To Type I Interferon Regulation Of Immune Response Transcription From RNA Polymerase II Promoter Immune Response Cellular Response To Cytokine Stimulus Nitrogen Compound Metabolic Process Regulation Of Type I Interferon-mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Response To Cytokine Regulation Of Interleukin-12 Production Cellular Response To Nicotine Cytokine-mediated Signaling Pathway Response To Mechanical Stimulus Innate Immune Response Positive Regulation Of Type I Interferon Production Developmental Process Regulation Of MiRNA Metabolic Process Response To External Stimulus Regulation Of Immune System Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Positive Regulation Of Transcription, DNA-templated
Tagcloud ?			antiviral attenuated defense enhancement essential failed guanylate iav ifn impaired induces inducible infection influenza interference interferon isg15 isg20 isgs knockdown knocked oligoadenylate p53 pretreatment replication retinoic secretion synthetase
Tagcloud (Difference) ?			antiviral attenuated defense enhancement essential failed guanylate iav ifn impaired induces inducible infection influenza interference interferon isg15 isg20 isgs knockdown knocked oligoadenylate p53 pretreatment replication retinoic secretion synthetase
Tagcloud (Intersection) ?