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DMRTC2 and TXNRD1
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
DMRTC2
TXNRD1
Gene Name
DMRT-like family C2
thioredoxin reductase 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
XY Body
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Extracellular Vesicular Exosome
Molecular Function
Core Promoter Proximal Region Sequence-specific DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Homodimerization Activity
Metal Ion Binding
Thioredoxin-disulfide Reductase Activity
Protein Binding
Electron Carrier Activity
Protein Disulfide Oxidoreductase Activity
Flavin Adenine Dinucleotide Binding
Biological Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Male Meiosis I
Spermatid Nucleus Elongation
Sex Differentiation
Positive Regulation Of Histone H3-K9 Dimethylation
Positive Regulation Of Histone H3-K9 Trimethylation
Response To Reactive Oxygen Species
Signal Transduction
Nucleobase-containing Small Molecule Interconversion
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Cell Redox Homeostasis
Nucleobase-containing Small Molecule Metabolic Process
Oxidation-reduction Process
Pathways
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Uptake and actions of bacterial toxins
Metabolism of lipids and lipoproteins
Detoxification of Reactive Oxygen Species
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Metabolism of nucleotides
Synthesis and interconversion of nucleotide di- and triphosphates
Uptake and function of diphtheria toxin
Drugs
Arsenic trioxide
Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate
Flavin-Adenine Dinucleotide
Spermidine
Fotemustine
Diseases
GWAS
Protein-Protein Interactions
2 interactors:
IRF9
TXNRD1
8 interactors:
DMRTC2
FOXO1
GLRX2
POU2F1
POU2F2
PPP1R16A
TXNDC17
TXNIP
Entrez ID
63946
7296
HPRD ID
16829
03068
Ensembl ID
ENSG00000142025
ENSG00000198431
Uniprot IDs
Q8IXT2
B7Z1F4
B7Z2S5
B7Z904
E7EW10
Q16881
PDB IDs
1W1C
2CFY
2J3N
2ZZ0
2ZZB
2ZZC
3QFA
3QFB
Enriched GO Terms of Interacting Partners
?
Detoxification Of Mercury Ion
Type I Interferon Biosynthetic Process
Type I Interferon Production
Nucleobase-containing Small Molecule Interconversion
Response To Mercury Ion
Cytokine Biosynthetic Process
Cytokine Metabolic Process
Response To Reactive Oxygen Species
Cell Differentiation
Transcription, DNA-templated
RNA Biosynthetic Process
Response To Oxidative Stress
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Response To Inorganic Substance
Regulation Of RNA Metabolic Process
Cellular Response To Tumor Cell
Positive Regulation Of Histone H3-K9 Dimethylation
Positive Regulation Of Histone H3-K9 Trimethylation
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Immunoglobulin Secretion Involved In Immune Response
DNA Protection
Response To Hydrogen Peroxide
RNA Metabolic Process
Developmental Process
Nitrogen Compound Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Response To Temperature Stimulus
Macromolecule Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Cellular Response To Extracellular Stimulus
Response To Tumor Cell
Immunoglobulin Secretion
Olfactory Placode Formation
Cellular Response To Cold
Spermatid Nucleus Elongation
Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Hyperoxia
Response To Abiotic Stimulus
Negative Regulation Of Transcription, DNA-templated
Lens Induction In Camera-type Eye
Positive Regulation Of Histone H3-K9 Methylation
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Response To Organic Substance
Regulation Of Energy Homeostasis
Positive Regulation Of Cellular Metabolic Process
Cellular Response To Nitric Oxide
Response To Redox State
Response To Nitric Oxide
Tagcloud
?
bring
btg1
cyr61
dcs
e7
epha1
hla
idc
idcs
igfbp3
igsf6
il8
kpna7
mdc
mdcs
mrps11
ncr3
nfkb1a
nfkbia
padre
pgf
pidc
pulsed
pulsing
rad21
sema6a
srgn
trem2
tubal3
Tagcloud (Difference)
?
bring
btg1
cyr61
dcs
e7
epha1
hla
idc
idcs
igfbp3
igsf6
il8
kpna7
mdc
mdcs
mrps11
ncr3
nfkb1a
nfkbia
padre
pgf
pidc
pulsed
pulsing
rad21
sema6a
srgn
trem2
tubal3
Tagcloud (Intersection)
?