UBE2O and RNF10

Number of citations of the paper that reports this interaction (PMID 19549727)
40

Data Source:
BioGRID (two hybrid)

		UBE2O	RNF10
Gene Name		ubiquitin-conjugating enzyme E2O	ring finger protein 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Poly(A) RNA Binding Ubiquitin Protein Ligase Activity	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transcription Regulatory Region DNA Binding
	Biological Process	Protein Monoubiquitination Positive Regulation Of BMP Signaling Pathway Retrograde Transport, Endosome To Golgi Protein K63-linked Ubiquitination	Transcription, DNA-templated Negative Regulation Of Schwann Cell Proliferation Positive Regulation Of Myelination Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Autoubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS			Type 1 diabetes nephropathy ( 23028342)
Protein-Protein Interactions		8 interactors: APPL1 BAP1 CPNE1 CPNE2 CPNE4 RNF10 SHBG TRIM27	28 interactors: CCDC90B COL4A5 EEF1A1 GRB2 KDM1A LRIF1 MDM2 SETDB1 SNCA TERF1 TLE1 TRIM26 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2J2 UBE2O UBE2U UBE2V1 UBE2W UBTD1 UTP14A
Entrez ID		63893	9921
HPRD ID		10928	11496
Ensembl ID		ENSG00000175931	ENSG00000022840
Uniprot IDs		Q9C0C9	B3KWY9 Q8N5U6
PDB IDs
Enriched GO Terms of Interacting Partners?		Primary Spermatocyte Growth Protein Ubiquitination Protein Modification By Small Protein Conjugation Negative Regulation Of Interleukin-2 Secretion Histone H2A-K119 Monoubiquitination Negative Regulation Of Schwann Cell Proliferation Monoubiquitinated Histone H2A Deubiquitination Negative Regulation Of Calcium Ion Import Interferon-gamma Secretion	Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K63-linked Ubiquitination Protein Catabolic Process Cellular Protein Modification Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Metabolic Process Negative Regulation Of Chromosome Organization Protein Metabolic Process Protein Monoubiquitination Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Catabolic Process Innate Immune Response Toll-like Receptor 4 Signaling Pathway Cellular Response To Stress Proteolysis Regulation Of Chromosome Organization Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Mitotic Cell Cycle Phase Transition Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Cell Cycle Phase Transition Toll-like Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Cellular Response To Oxygen Levels Mitotic Spindle Assembly Checkpoint Immune Response-regulating Signaling Pathway Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Transcription, DNA-templated Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Negative Regulation Of Chromosome Segregation Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of RNA Biosynthetic Process Activation Of Innate Immune Response Response To Stress Negative Regulation Of Mitotic Cell Cycle Phase Transition
Tagcloud ?		c4a cascades coagulation complement conjugating cytoskeleton declaration electrospray epiretinal esi esr1 genego helsinki hplc idiopathic ierm ierms ionization kegg metacore metalloproteinase proteome proteomes remolding rp tenets top vitreous
Tagcloud (Difference) ?		c4a cascades coagulation complement conjugating cytoskeleton declaration electrospray epiretinal esi esr1 genego helsinki hplc idiopathic ierm ierms ionization kegg metacore metalloproteinase proteome proteomes remolding rp tenets top vitreous
Tagcloud (Intersection) ?