UBE2O and CPNE1

Number of citations of the paper that reports this interaction (PMID 12522145)
20

Data Source:
HPRD (two hybrid, in vitro)

		UBE2O	CPNE1
Gene Name		ubiquitin-conjugating enzyme E2O	copine I
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Extracellular Vesicular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Poly(A) RNA Binding Ubiquitin Protein Ligase Activity	Phosphatidylserine Binding Transporter Activity Calcium-dependent Phospholipid Binding
	Biological Process	Protein Monoubiquitination Positive Regulation Of BMP Signaling Pathway Retrograde Transport, Endosome To Golgi Protein K63-linked Ubiquitination	Lipid Metabolic Process Vesicle-mediated Transport
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: APPL1 BAP1 CPNE1 CPNE2 CPNE4 RNF10 SHBG TRIM27	18 interactors: ACTB BCOR BUB3 CCDC22 CPNE4 LIG4 MAP2K1 MYCBP PDCD6 PITPNM2 PPP5C RDX SKIL SPTBN1 STK3 UBE2M UBE2O WTAP
Entrez ID		63893	8904
HPRD ID		10928	05014
Ensembl ID		ENSG00000175931	ENSG00000214078
Uniprot IDs		Q9C0C9	B0QZ18 Q99829
PDB IDs
Enriched GO Terms of Interacting Partners?		Primary Spermatocyte Growth Protein Ubiquitination Protein Modification By Small Protein Conjugation Negative Regulation Of Interleukin-2 Secretion Histone H2A-K119 Monoubiquitination Negative Regulation Of Schwann Cell Proliferation Monoubiquitinated Histone H2A Deubiquitination Negative Regulation Of Calcium Ion Import Interferon-gamma Secretion	Cell Cycle Enzyme Linked Receptor Protein Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Protein Heterooligomerization Regulation Of Cellular Process Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Regulation Of Cellular Component Organization Golgi To Plasma Membrane Transport Regulation Of Organelle Organization In Utero Embryonic Development Protein Monoubiquitination Generation Of Neurons Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Cell Cycle Process Actin Filament Capping Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Neurogenesis Negative Regulation Of Histone H3-K36 Methylation DNA Ligation Involved In DNA Recombination Positive Regulation Of Cell Death Anatomical Structure Morphogenesis Negative Regulation Of Actin Filament Depolymerization Regulation Of Intracellular Signal Transduction Mitotic Cell Cycle Process Cellular Protein Metabolic Process Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Mitotic Nuclear Division Cellular Component Assembly Negative Regulation Of Tooth Mineralization Protein Metabolic Process Mitotic Cell Cycle Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Polymerization Post-Golgi Vesicle-mediated Transport Regulation Of Signal Transduction Negative Regulation Of Chromosome Organization Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Negative Regulation Of Protein Complex Disassembly Axon Guidance Positive Regulation Of Cell Differentiation Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Apoptotic Process Regulation Of Protein Depolymerization
Tagcloud ?		c4a cascades coagulation complement conjugating cytoskeleton declaration electrospray epiretinal esi esr1 genego helsinki hplc idiopathic ierm ierms ionization kegg metacore metalloproteinase proteome proteomes remolding rp tenets top vitreous	affect arrangement cdnas coding connection conservation copine courses ests evolutionary exons genome genomic indicates initiated motif pairs phenomenon promoters rbm12 sequences share sharing shed splicing tags totally utr zebrafish
Tagcloud (Difference) ?		c4a cascades coagulation complement conjugating cytoskeleton declaration electrospray epiretinal esi esr1 genego helsinki hplc idiopathic ierm ierms ionization kegg metacore metalloproteinase proteome proteomes remolding rp tenets top vitreous	affect arrangement cdnas coding connection conservation copine courses ests evolutionary exons genome genomic indicates initiated motif pairs phenomenon promoters rbm12 sequences share sharing shed splicing tags totally utr zebrafish
Tagcloud (Intersection) ?