UBE2O and BAP1

Number of citations of the paper that reports this interaction (PMID 24703950)
0

Data Source:
BioGRID (enzymatic study, pull down)

		UBE2O	BAP1
Gene Name		ubiquitin-conjugating enzyme E2O	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Cytoplasm PR-DUB Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Poly(A) RNA Binding Ubiquitin Protein Ligase Activity	Chromatin Binding Ubiquitin-specific Protease Activity Protein Binding Peptidase Activity
	Biological Process	Protein Monoubiquitination Positive Regulation Of BMP Signaling Pathway Retrograde Transport, Endosome To Golgi Protein K63-linked Ubiquitination	Regulation Of Cell Growth Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Proliferation Protein Deubiquitination Monoubiquitinated Protein Deubiquitination Monoubiquitinated Histone H2A Deubiquitination Regulation Of Cell Cycle Protein K48-linked Deubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		8 interactors: APPL1 BAP1 CPNE1 CPNE2 CPNE4 RNF10 SHBG TRIM27	10 interactors: BRCA1 HIST2H2AA3 HIST2H2AC TRIM63 UBE2O USP15 USP2 USP21 USP28 YY1
Entrez ID		63893	8314
HPRD ID		10928	04366
Ensembl ID		ENSG00000175931	ENSG00000163930
Uniprot IDs		Q9C0C9	Q92560
PDB IDs
Enriched GO Terms of Interacting Partners?		Primary Spermatocyte Growth Protein Ubiquitination Protein Modification By Small Protein Conjugation Negative Regulation Of Interleukin-2 Secretion Histone H2A-K119 Monoubiquitination Negative Regulation Of Schwann Cell Proliferation Monoubiquitinated Histone H2A Deubiquitination Negative Regulation Of Calcium Ion Import Interferon-gamma Secretion	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein Deubiquitination Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Macromolecule Catabolic Process Regulation Of Protein Catabolic Process Response To Radiation Histone Deubiquitination Response To Abiotic Stimulus Cellular Protein Modification Process Regulation Of Proteolysis Proteolysis Cellular Response To UV Response To Light Stimulus Catabolic Process Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Cellular Protein Metabolic Process Double-strand Break Repair Via Homologous Recombination Recombinational Repair Regulation Of Cellular Protein Metabolic Process Cellular Response To Light Stimulus Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Histone H3-K9 Acetylation Histone H2B Conserved C-terminal Lysine Deubiquitination Response To Prostaglandin F Signal Transduction By P53 Class Mediator Regulation Of Protein Metabolic Process Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Response To UV Protein Ubiquitination Cellular Response To Radiation DNA Repair Response To Ionizing Radiation Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Protein Modification By Small Protein Conjugation Double-strand Break Repair DNA Damage Checkpoint Cellular Response To Indole-3-methanol Protein Metabolic Process Protein Polyubiquitination Negative Regulation Of Centriole Replication Skeletal Muscle Atrophy
Tagcloud ?		c4a cascades coagulation complement conjugating cytoskeleton declaration electrospray epiretinal esi esr1 genego helsinki hplc idiopathic ierm ierms ionization kegg metacore metalloproteinase proteome proteomes remolding rp tenets top vitreous	1000x abstracted arid1a cca cdkn2a cholangiocarcinoma entities extrahepatic fbxw7 fgfr gas hiseq hotspot idh1 illumina indolent intrahepatic introns kras mcl1 ngs pbrm1 pgm presentations radiologic sequencer smad4 targetable worse
Tagcloud (Difference) ?		c4a cascades coagulation complement conjugating cytoskeleton declaration electrospray epiretinal esi esr1 genego helsinki hplc idiopathic ierm ierms ionization kegg metacore metalloproteinase proteome proteomes remolding rp tenets top vitreous	1000x abstracted arid1a cca cdkn2a cholangiocarcinoma entities extrahepatic fbxw7 fgfr gas hiseq hotspot idh1 illumina indolent intrahepatic introns kras mcl1 ngs pbrm1 pgm presentations radiologic sequencer smad4 targetable worse
Tagcloud (Intersection) ?